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The main objective of this study is to evaluate the efficacy of venetoclax in combination with azacitidine to improve Overall Survival (OS) in Acute...
Phase 3
Baltimore, Maryland, United States and 164 other locations
allogeneic hematopoietic stem cell transplant (HCT), versus Conventional Care in patients with Active, Relapsed or Refractory Acute Myeloid...
Phase 3
Washington, District of Columbia, United States and 23 other locations
People with acute myeloid leukemia (AML) are usually treated with chemotherapy. Some people with AML hav...
Phase 1, Phase 2
Baltimore, Maryland, United States and 19 other locations
the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity, and preliminary anti-leukemic activity of WU-NK-101 in R/R AML....
Phase 1
Baltimore, Maryland, United States and 8 other locations
The purpose of this Phase I, multicenter, clinical trial is to evaluate the safety of AG-120 and AG-221 when given in combination with standard AML...
Phase 1
Baltimore, Maryland, United States and 16 other locations
This trial will evaluate whether luveltamab tazevibulin is well tolerated and active against a rare form of AML carrying a particular geneti...
Phase 1, Phase 2
Washington, District of Columbia, United States and 3 other locations
or young adults with a certain kind of blood cancer (FLT3-ITD AML) might be able to join this study if it has come back after remission or i...
Phase 1, Phase 2
Washington, District of Columbia, United States and 26 other locations
Eligible untreated patients with FLT3 acute myeloid leukemia (AML) between the ages of 18 and 70 will be randomiz...
Phase 2
Baltimore, Maryland, United States and 43 other locations
This is a phase IB/II study with a 3+3 dose de-escalation study design. Patients will continue maintenance treatment with CPX-351 for 6 cycles on D1...
Phase 1, Phase 2
Washington, District of Columbia, United States and 2 other locations
This is a Phase 1/2a, multicenter, open-label, first-in-human (FIH) study of VOR33 in participants with AML or MDS who are undergoing human ...
Phase 1, Phase 2
Bethesda, Maryland, United States and 14 other locations
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