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to be used in future studies in study participants diagnosed with acute myeloid leukemia (AML), myelodysplastic s...
Phase 1, Phase 2
Boston, Massachusetts, United States and 33 other locations
CLN-049-001 is a Phase 1/2, open-label, multicenter, first-in-human trial of CLN-049 in patients with Relapsed/Refractory Acute Myeloid...
Phase 1, Phase 2
Boston, Massachusetts, United States and 16 other locations
3) mutated Acute Myeloid Leukemia (AML).The names of the study drugs involved in this study are:* Revumenib (SNDX...
Phase 1
Boston, Massachusetts, United States and 1 other location
The purpose of this study is to determine the recommended Phase 2 dose (RP2D) candidate(s) of bleximenib in combination with AML directed th...
Phase 1
Boston, Massachusetts, United States and 33 other locations
The purpose of this Phase I, multicenter, clinical trial is to evaluate the safety of AG-120 and AG-221 when given in combination with standard AML...
Phase 1
Boston, Massachusetts, United States and 16 other locations
agents, azacitidine, venetoclax and tagraxofusp. Leftover (residual) leukemia disease that is not visible by eye can be increase the chance ...
Phase 1, Phase 2
Boston, Massachusetts, United States and 1 other location
This is a Phase 2 study of the study drug, ivosidenib (a mutant IDH1 inhibitor), compared to placebo, given to patients with IDH1-mutant acute...
Phase 2
Boston, Massachusetts, United States and 6 other locations
This research study is studying a drug as a possible treatment for diagnosis of AML, BPDCN and high-risk MDS.The interventions involved in t...
Phase 1
Boston, Massachusetts, United States and 2 other locations
preliminary efficacy of STX-0712 in patients with advanced CMML and AML for whom there are no further treatment options known to confer clin...
Phase 1
Boston, Massachusetts, United States and 6 other locations
Ziftomenib is an investigational drug in development for the treatment of patients with acute myeloid leukemia (AML...
Phase 3
Worcester, Massachusetts, United States of America and 133 other locations
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