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The purpose of this study is to determine the clinical benefit of ASP2215 therapy in participants with FMS-like tyrosine kinase (FLT3) mutated acute...
Phase 3
Chicago, Illinois, United States and 125 other locations
The main objective of this study is to evaluate the efficacy of venetoclax in combination with azacitidine to improve Overall Survival (OS) in Acute...
Phase 3
Chicago, Illinois, United States and 164 other locations
Acute myeloid leukemia (AML) is the second most common type of leukemia diagnosed in adults and children ...
Phase 1
Chicago, Illinois, United States and 23 other locations
allogeneic hematopoietic stem cell transplant (HCT), versus Conventional Care in patients with Active, Relapsed or Refractory Acute Myeloid...
Phase 3
Maywood, Illinois, United States and 23 other locations
People with acute myeloid leukemia (AML) are usually treated with chemotherapy. Some people with AML hav...
Phase 1, Phase 2
Chicago, Illinois, United States and 18 other locations
The purpose of this Phase I, multicenter, clinical trial is to evaluate the safety of AG-120 and AG-221 when given in combination with standard AML...
Phase 1
Chicago, Illinois, United States and 16 other locations
To assess safety and tolerability at increasing dose levels of IO-202 in successive cohorts of participants with AML with monocytic differen...
Phase 1
Chicago, Illinois, United States and 13 other locations
subjects with previously treated or untreated with high risk factor acute myeloid leukemia (AML). Venetoclax and ...
Phase 1
Skokie, Illinois, United States of America and 3 other locations
\[GO\]) improves survival of children/adolescents/young adults with acute myeloid leukemia (AML) in 1st relapse w...
Phase 3
Chicago, Illinois, United States and 78 other locations
This study will be conducted in two parts. Part 1 will be the Dose Confirmation portion to determine recommended Phase 3 dose (RPTD) of venetoclax in...
Phase 3
Chicago, Illinois, United States and 160 other locations
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