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CLN-049-001 is a Phase 1, open-label, multicenter, first-in-human trial of CLN-049 in patients with Relapsed/Refractory Acute Myeloid...
Phase 1
Cincinnati, Ohio, United States and 6 other locations
study of five dose levels of APVO436 in combination with venetoclax and azacitidine (ven/aza) in adult patients with newly diagnosed, CD123+ AML...
Phase 1
Cincinnati,, Ohio, United States and 6 other locations
or young adults with a certain kind of blood cancer (FLT3-ITD AML) might be able to join this study if it has come back after remission or i...
Phase 1, Phase 2
Cincinnati, Ohio, United States and 26 other locations
Eligible untreated patients with FLT3 acute myeloid leukemia (AML) between the ages of 18 and 70 will be randomiz...
Phase 2
Cincinnati, Ohio, United States and 43 other locations
Refractory Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML), or Acute Myeloid Leukemia (AML...
Phase 1
Cincinnati, Ohio, United States and 6 other locations
inhibitor of MDM2 for the treatment of adults with FLT3 mutated Acute Myeloid Leukemia. Participants must be relapsed/refr...
Phase 1, Phase 2
Cincinnati, Ohio, United States and 34 other locations
This is a multi-center, randomized, double-blinded, placebo controlled trial.
Phase 3
Cincinnati, Ohio, United States and 104 other locations
combination with chemotherapy in participants with newly diagnosed FMS-like tyrosine kinase 3 (FLT3)-internal tandem duplication (ITD) negative acute...
Phase 3
Cincinnati, Ohio, United States and 277 other locations
safe and if they have beneficial effects in treating patients with acute myeloid leukemia (AML) or acute ...
Phase 1
Cincinnati, Ohio, United States and 5 other locations
with fludarabine and cytarabine in treating patients with acute myeloid leukemia (AML), myelodysplastic syndrome ...
Phase 1
Cincinnati, Ohio, United States and 17 other locations
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