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Find clinical trials for Acute Myeloid Leukemia (AML) in Cincinnati, OH

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Related conditions:

Leukemia
Acute Myeloid Leukemia
Myeloid Leukemia
Myelodysplastic Syndromes
Preleukemia
Syndrome
Cancer

Acute Myeloid Leukemia (AML) trials near Cincinnati, OH, USA:

A Study Evaluating Safety and Efficacy of Venetoclax in Combination With Azacitidine Versus Standard of Care After Allogeneic Stem Cell Transplantation (SCT) in Participants With Acute Myeloid Leukemia (AML) (VIALE-T)

The main objective of this study is to evaluate the efficacy of venetoclax in combination with azacitidine to improve Overall Survival (OS) in Acute...

Active, not recruiting
Acute Myeloid Leukemia (AML)
Cancer
Other: Best Supportive Care (BSC)
Drug: Venetoclax

Phase 3

AbbVie
AbbVie

Cincinnati, Ohio, United States and 164 other locations

The purpose of the phase 1 portion (dose escalation) of the study will be to establish an optimally safe and biologically active recommended phase 2...

Enrolling
Acute Myeloid Leukemia With FMS-like Tyrosine Kinase 3 (FLT3) Mutation / Internal Tandem Duplication (ITD)
Acute Myeloid Leukemia (AML)
Drug: fludarabine
Drug: cytarabine

Phase 1, Phase 2

Astellas
Astellas

Cincinnati, Ohio, United States and 24 other locations

CLN-049-001 is a Phase 1, open-label, multicenter, first-in-human trial of CLN-049 in patients with Relapsed/Refractory Acute Myeloid...

Enrolling
Relapsed/Refractory Acute Myeloid Leukemia (AML)
Myelodysplastic Syndrome (MDS)
Drug: CLN-049

Phase 1

Cullinan Oncology Inc.

Cincinnati, Ohio, United States and 6 other locations

or young adults with a certain kind of blood cancer (FLT3-ITD AML) might be able to join this study if it has come back after remission or i...

Enrolling
Acute Myeloid Leukemia
Drug: Quizartinib
Drug: Etoposide

Phase 1, Phase 2

Daiichi Sankyo
Daiichi Sankyo

Cincinnati, Ohio, United States and 36 other locations

Eligible untreated patients with FLT3 acute myeloid leukemia (AML) between the ages of 18 and 70 will be randomiz...

Active, not recruiting
Acute Myeloid Leukemia
Drug: Gilteritinib
Drug: Daunorubicin

Phase 2

PrECOG

Cincinnati, Ohio, United States and 43 other locations

Refractory Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML), or Acute Myeloid Leukemia (AML...

Enrolling
Relapsed Adult AML
AML/MDS
Drug: LP-108 and azacitidine
Drug: LP-108

Phase 1

Newave Pharmaceutical

Cincinnati, Ohio, United States and 6 other locations

inhibitor of MDM2 for the treatment of adults with FLT3 mutated Acute Myeloid Leukemia. Participants must be relapsed/refr...

Active, not recruiting
Acute Myeloid Leukemia
Drug: TL-895
Drug: KRT-232

Phase 1, Phase 2

Telios Pharma

Cincinnati, Ohio, United States and 34 other locations

SL03-Old Hundred(OHD)-104 is designed as a Phase 1a/1b open label, trial to evaluate the safety, pharmacokinetics (PK), pharmacodynamic (PD), and pre...

Enrolling
Acute Myeloid Leukemia
Myelodysplastic Syndromes
Drug: SL-172154

Phase 1

Shattuck Labs

Cincinnati, Ohio, United States and 23 other locations

(mCRPC), higher risk myelodysplastic syndrome (HRMDS), acute myeloid leukemia (AML) and newly diagnosed intermed...

Active, not recruiting
Acute Myeloid Leukemia (AML)
Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Drug: ASTX727
Drug: Dexamethasone

Phase 1, Phase 2

Karyopharm Therapeutics
Karyopharm Therapeutics

Cincinnati, Ohio, United States and 45 other locations

A Phase 1 first-in-human dose-escalation and dose-expansion study of BMF-219, an oral covalent menin inhibitor, in adult patients with AML, ...

Enrolling
Acute Mixed-Phenotype Leukemia
Chronic Lymphocytic Leukemia
Drug: BMF-219

Phase 1

Biomea Fusion

Cincinnati, Ohio, United States and 40 other locations

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