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The main objective of this study is to evaluate the efficacy of venetoclax in combination with azacitidine to improve Overall Survival (OS) in Acute...
Phase 3
Dallas, Texas, United States and 164 other locations
allogeneic hematopoietic stem cell transplant (HCT), versus Conventional Care in patients with Active, Relapsed or Refractory Acute Myeloid...
Phase 3
Dallas, Texas, United States and 23 other locations
The purpose of this Phase I, multicenter, clinical trial is to evaluate the safety of AG-120 and AG-221 when given in combination with standard AML...
Phase 1
Dallas, Texas, United States and 16 other locations
To assess safety and tolerability at increasing dose levels of IO-202 in successive cohorts of participants with AML with monocytic differen...
Phase 1
Dallas, Texas, United States and 13 other locations
or young adults with a certain kind of blood cancer (FLT3-ITD AML) might be able to join this study if it has come back after remission or i...
Phase 1, Phase 2
Dallas, Texas, United States and 36 other locations
[GO]) improves survival of children/adolescents/young adults with acute myeloid leukemia (AML) in 1st relapse who...
Phase 3
Dallas, Texas, United States and 71 other locations
A study of siremadlin in combination with venetoclax plus azacitidine in adult participants with AML who are ineligible for chemotherapy.The...
Phase 1
Dallas, Texas, United States and 9 other locations
This study will be conducted in two parts. Part 1 will be the Dose Confirmation portion to determine recommended Phase 3 dose (RPTD) of venetoclax in...
Phase 3
Dallas, Texas, United States and 157 other locations
combination with all-trans retinoic acid (ATRA) in participants with acute myeloid leukemia (AML) who have relaps...
Phase 1
Dallas, Texas, United States and 7 other locations
This study enrolled 472 participants, aged 55 or older, with a diagnosis of de novo acute myeloid leukemia (AML) ...
Phase 3
Dallas, Texas, United States and 222 other locations
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