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Acute myeloid leukemia (AML) is the second most common type of leukemia diagnosed in adults and children ...
Phase 1
Houston, Texas, United States and 23 other locations
CLN-049-001 is a Phase 1, open-label, multicenter, first-in-human trial of CLN-049 in patients with Relapsed/Refractory Acute Myeloid...
Phase 1
Houston, Texas, United States and 6 other locations
to be used in future studies in study participants diagnosed with acute myeloid leukemia (AML), myelodysplastic s...
Phase 1, Phase 2
Houston, Texas, United States and 33 other locations
allogeneic hematopoietic stem cell transplant (HCT), versus Conventional Care in patients with Active, Relapsed or Refractory Acute Myeloid...
Phase 3
Houston, Texas, United States and 23 other locations
People with acute myeloid leukemia (AML) are usually treated with chemotherapy. Some people with AML hav...
Phase 1, Phase 2
Houston, Texas, United States and 18 other locations
Antisense Oligodeoxynucleotide) in patients with refractory/relapsed AML. The study is designed to assess the safety profile, identify DLTs,...
Phase 1
Houston, Texas, United States and 3 other locations
PK of APG-2575 in combination with Azacitidine in the patients with AML/MPAL or MDS/CMML. The study consists of dose escalation (Part I) and...
Phase 1, Phase 2
Houston, Texas, United States and 8 other locations
The purpose of this study is to determine the recommended Phase 2 dose (RP2D) candidate(s) of bleximenib in combination with AML directed th...
Phase 1
Houston, Texas, United States and 30 other locations
To find a recommended dose of ASTX727 (cedazuridine/decitabine) in combination with venetoclax for pediatric patients with relapsed AML....
Phase 1
Houston, Texas, United States
The purpose of this Phase I, multicenter, clinical trial is to evaluate the safety of AG-120 and AG-221 when given in combination with standard AML...
Phase 1
Houston, Texas, United States and 16 other locations
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