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Find clinical trials for Acute Myeloid Leukemia (AML) in Indianapolis, IN

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Related conditions:

Acute Myeloid Leukemia
Leukemia
Myeloid Leukemia
Myelodysplastic Syndromes
Preleukemia
Syndrome
Cancer

Acute Myeloid Leukemia (AML) trials near Indianapolis, IN, USA:

A Study Evaluating Safety and Efficacy of Venetoclax in Combination With Azacitidine Versus Standard of Care After Allogeneic Stem Cell Transplantation (SCT) in Participants With Acute Myeloid Leukemia (AML) (VIALE-T)

The main objective of this study is to evaluate the efficacy of venetoclax in combination with azacitidine to improve Overall Survival (OS) in Acute...

Active, not recruiting
Acute Myeloid Leukemia (AML)
Cancer
Other: Best Supportive Care (BSC)
Drug: Venetoclax

Phase 3

AbbVie
AbbVie

Indianapolis, Indiana, United States and 164 other locations

or young adults with a certain kind of blood cancer (FLT3-ITD AML) might be able to join this study if it has come back after remission or i...

Enrolling
Acute Myeloid Leukemia
Drug: Quizartinib
Drug: Etoposide

Phase 1, Phase 2

Daiichi Sankyo
Daiichi Sankyo

Indianapolis, Indiana, United States and 36 other locations

This study enrolled 472 participants, aged 55 or older, with a diagnosis of de novo acute myeloid leukemia (AML) ...

Active, not recruiting
Leukemia, Myeloid, Acute
Drug: Placebo
Drug: Oral Azacitidine

Phase 3

Celgene
Celgene

Indianapolis, Indiana, United States and 222 other locations

Eligible untreated patients with FLT3 acute myeloid leukemia (AML) between the ages of 18 and 70 will be randomiz...

Active, not recruiting
Acute Myeloid Leukemia
Drug: Gilteritinib
Drug: Daunorubicin

Phase 2

PrECOG

Indianapolis, Indiana, United States and 43 other locations

in combination with venetoclax for the treatment of newly diagnosed acute myeloid leukemia (AML) in adults who ar...

Active, not recruiting
Acute Myeloid Leukemia
Drug: Venetoclax
Drug: Decitabine and Cedazuridine (ASTX727)

Phase 1, Phase 2

Astex Pharmaceuticals
Astex Pharmaceuticals

Indianapolis, Indiana, United States and 33 other locations

menin-MLL(KMT2A) inhibitor, in patients with relapsed or refractory acute myeloid leukemia (AML) as part of Phase....

Enrolling
Acute Leukemia of Ambiguous Lineage
Mixed Phenotype Acute Leukemia
Drug: Ziftomenib

Phase 1, Phase 2

Kura Oncology

Indianapolis, Indiana, United States and 51 other locations

with Gemtuzumab Ozogamicin(GO) in subjects with relapsed/refractory acute myeloid leukemia. Using a standard 3+3 design, s...

Active, not recruiting
Acute Myeloid Leukemia
Drug: Gemtuzumab Ozogamicin
Drug: Venetoclax

Phase 1

John Quigley

Indianapolis, Indiana, United States and 3 other locations

or refractory (R/R) lymphomamultiple myelomanewly diagnosed acute myeloid leukemia (AML).This trial will be condu...

Active, not recruiting
Acute Myeloid Leukemia
Multiple Myeloma
Drug: Dexamethasone
Drug: Venetoclax

Phase 1

Pfizer
Pfizer

Indianapolis, Indiana, United States and 61 other locations

myeloid leukemia (AML) in transfusion-dependent participants with low or immediate-1 risk MDS that is relapsed/refractory...

Active, not recruiting
Myelodysplastic Syndromes
Drug: Imetelstat
Drug: Placebo

Phase 2, Phase 3

Geron

Indianapolis, Indiana, United States and 126 other locations

Phase III, multicenter, randomized study with two arms (1:1 ratio) enrolling patients with AML relapsed/refractory after 2, 3, or 4 prior in...

Enrolling
Leukemia, Myeloid, Acute
Drug: Cladribine
Drug: Venetoclax

Phase 3

Delta-Fly Pharma

Indianapolis, Indiana, United States and 38 other locations

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