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Find clinical trials for Acute Myeloid Leukemia (AML) in Los Angeles, CA

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Related conditions:

Acute Myeloid Leukemia
Leukemia
Myeloid Leukemia
Myelodysplastic Syndromes
Preleukemia
Syndrome
Cancer

Acute Myeloid Leukemia (AML) trials near Los Angeles, CA, USA:

A Study of ASP2215 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase (FLT3) Mutation

The purpose of this study is to determine the clinical benefit of ASP2215 therapy in participants with FMS-like tyrosine kinase (FLT3) mutated acute...

Active, not recruiting
Leukemia, Acute Myeloid (AML)
Drug: LoDAC (Low Dose Cytarabine)
Drug: MEC (Mitoxantrone, Etoposide, Cytarabine)

Phase 3

Astellas
Astellas

Los Angeles, California, United States and 125 other locations

The main objective of this study is to evaluate the efficacy of venetoclax in combination with azacitidine to improve Overall Survival (OS) in Acute...

Active, not recruiting
Acute Myeloid Leukemia (AML)
Cancer
Other: Best Supportive Care (BSC)
Drug: Venetoclax

Phase 3

AbbVie
AbbVie

Duarte, California, United States and 164 other locations

Locations recently updated

Acute myeloid leukemia (AML) is the second most common type of leukemia diagnosed in adults and children ...

Enrolling
Acute Myeloid Leukemia
Drug: ABBV-787

Phase 1

AbbVie
AbbVie

Duarte, California, United States and 17 other locations

CLN-049-001 is a Phase 1, open-label, multicenter, first-in-human trial of CLN-049 in patients with Relapsed/Refractory Acute Myeloid...

Enrolling
Relapsed/Refractory Acute Myeloid Leukemia (AML)
Myelodysplastic Syndrome (MDS)
Drug: CLN-049

Phase 1

Cullinan Oncology Inc.

Los Angeles, California, United States and 6 other locations

People with acute myeloid leukemia (AML) are usually treated with chemotherapy. Some people with AML hav...

Enrolling
Acute Myeloid Leukemia (AML)
FLT3-mutated Acute Myeloid Leukemia
Drug: Venetoclax
Drug: Gilteritinib

Phase 1, Phase 2

Astellas
Astellas

Los Angeles, California, United States and 18 other locations

The purpose of this study is to determine the recommended Phase 2 dose (RP2D) candidate(s) of JNJ-75276617 in combination with AML directed ...

Enrolling
Leukemia, Myeloid, Acute
Drug: Azacitidine (AZA)
Drug: Cytarabine

Phase 1

Janssen (J&J Innovative Medicine)

Duarte, California, United States and 30 other locations

Antisense Oligodeoxynucleotide) in patients with refractory/relapsed AML. The study is designed to assess the safety profile, identify DLTs,...

Enrolling
Acute Myeloid Leukemia Refractory
Acute Myeloid Leukemia, in Relapse
Drug: Decitabine (in combination with BP1002)
Drug: BP1002; Liposomal Bcl-2 Antisense Oligodeoxynucleotide

Phase 1

Bio-Path

Los Angeles, California, United States and 3 other locations

PK of APG-2575 in combination with Azacitidine in the patients with AML/MPAL or MDS/CMML. The study consists of dose escalation (Part I) and...

Enrolling
AML, Adult
Drug: APG 2575 ramp up arm

Phase 1, Phase 2

Ascentage Pharma Group
Ascentage Pharma Group

Los Angeles, California, United States and 8 other locations

and fludarabine, in subjects with Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML) undergoing allog...

Enrolling
ACUTE MYELOID LEUKEMIA; AML
MYELODYSPLASTIC SYNDROME; MDS
Biological: Humanized anti-CD117 Monoclonal Antibody (JSP191)

Phase 1

Jasper Therapeutics

Duarte, California, United States and 5 other locations

the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity, and preliminary anti-leukemic activity of WU-NK-101 in R/R AML....

Enrolling
Acute Myeloid Leukemia
Biological: WU-NK-101

Phase 1

Wugen, Inc.

Duarte, California, United States and 8 other locations

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