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Find clinical trials for Acute Myeloid Leukemia (AML) in Philadelphia, PA

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Related conditions:

Acute Myeloid Leukemia
Leukemia
Myelodysplastic Syndromes
Myeloid Leukemia
Recurrence
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Chronic Myelomonocytic Leukemia

Acute Myeloid Leukemia (AML) trials near Philadelphia, PA, USA:

A Study of Gilteritinib, Venetoclax and Azacitidine as a Combined Treatment for People Newly Diagnosed With Acute Myeloid Leukemia

People with acute myeloid leukemia (AML) are usually treated with chemotherapy. Some people with AML hav...

Active, not recruiting
Acute Myeloid Leukemia (AML)
FLT3-mutated Acute Myeloid Leukemia
Drug: Azacitidine
Drug: Venetoclax

Phase 1, Phase 2

Astellas
Astellas

Philadelphia, Pennsylvania, United States and 19 other locations

This Phase 1, multicenter, open-label, dose escalation and dose optimization study is designed to assess the safety, tolerability, pharmacokinetics (...

Active, not recruiting
Relapsed/Refractory AML
Relapsed Acute Myeloid Leukemia (AML)
Drug: AUTX-703

Phase 1

Auron Therapeutics, Inc.

Philadelphia, Pennsylvania, United States and 8 other locations

combination with ruxolitinib in patients with relapsed or refractory acute myeloid leukemia (AML). All subjects w...

Active, not recruiting
Relapsed AML
Refractory AML
Drug: Ruxolitinib 5 MG
Biological: CART123 Cells

Phase 1

University of Pennsylvania
University of Pennsylvania

Philadelphia, Pennsylvania, United States

Ziftomenib is an investigational drug in development for the treatment of patients with acute myeloid leukemia (AML...

Enrolling
Acute Myeloid Leukemia (AML)
Drug: Daunorubicin
Drug: Azacitidine (AZA)

Phase 3

Kura Oncology

Philadelphia, Pennsylvania, United States and 105 other locations

or young adults with a certain kind of blood cancer (FLT3-ITD AML) might be able to join this study if it has come back after remission or i...

Active, not recruiting
Acute Myeloid Leukemia
Drug: Quizartinib
Drug: Cytarabine

Phase 1, Phase 2

Daiichi Sankyo
Daiichi Sankyo

Wilmington, Delaware, United States and 26 other locations

Ziftomenib is an investigational drug in development for the treatment of patients with acute myeloid leukemia (AML...

Enrolling
Myeloid Sarcoma
Nucleophosmin 1-mutated Acute Myeloid Leukemia
Drug: Venetoclax
Drug: Cytarabine

Phase 1

Kura Oncology

Philadelphia, Pennsylvania, United States and 43 other locations

\[GO\]) improves survival of children/adolescents/young adults with acute myeloid leukemia (AML) in 1st relapse w...

Enrolling
Acute Myeloid Leukemia
Drug: Venetoclax
Drug: Fludarabine

Phase 3

PedAL BCU, LLC

Philadelphia, Pennsylvania, United States and 89 other locations

This is a phase IB/II study with a 3+3 dose de-escalation study design. Patients will continue maintenance treatment with CPX-351 for 6 cycles on D1...

Enrolling
Acute Myeloid Leukemia (AML) in Remission
Drug: CPX-351

Phase 1, Phase 2

Georgetown University
Georgetown University

Philadelphia, Pennsylvania, United States and 2 other locations

cytotoxic chemotherapy in induction-eligible patients with acute myeloid leukemia.This study involves the following:* Vene...

Active, not recruiting
Acute Myeloid Leukemia
Drug: Venetoclax
Drug: Azacitidine

Phase 2

Mass General Brigham
Mass General Brigham

Philadelphia, Pennsylvania, United States and 8 other locations

inhibitor of MDM2 for the treatment of adults with FLT3 mutated Acute Myeloid Leukemia. Participants must be relapsed/refr...

Active, not recruiting
Acute Myeloid Leukemia
Drug: TL-895
Drug: KRT-232

Phase 1, Phase 2

Telios Pharma

Philadelphia, Pennsylvania, United States and 34 other locations

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