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Find clinical trials for Acute Myeloid Leukemia (AML) in Pittsburgh, PA

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Related conditions:

Acute Myeloid Leukemia
Leukemia
Myelodysplastic Syndromes
Myeloid Leukemia
Recurrence
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Chronic Myelomonocytic Leukemia

Acute Myeloid Leukemia (AML) trials near Pittsburgh, PA, USA:

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

Ziftomenib is an investigational drug in development for the treatment of patients with acute myeloid leukemia (AML...

Enrolling
Acute Myeloid Leukemia (AML)
Drug: Daunorubicin
Drug: Azacitidine (AZA)

Phase 3

Kura Oncology

Wheeling, West Virginia, United States and 81 other locations

or young adults with a certain kind of blood cancer (FLT3-ITD AML) might be able to join this study if it has come back after remission or i...

Active, not recruiting
Acute Myeloid Leukemia
Drug: Quizartinib
Drug: Cytarabine

Phase 1, Phase 2

Daiichi Sankyo
Daiichi Sankyo

Pittsburgh, Pennsylvania, United States and 26 other locations

will be evaluated in patients with relapsed or refractory (R/R) acute myeloid leukemia (AML). The main study has ...

Active, not recruiting
Acute Leukemia of Ambiguous Lineage
Mixed Phenotype Acute Leukemia
Drug: Ziftomenib
Drug: Itraconazole

Phase 1, Phase 2

Kura Oncology

Pittsburgh, Pennsylvania, United States and 43 other locations

in combination with venetoclax for the treatment of newly diagnosed acute myeloid leukemia (AML) in adults who ar...

Active, not recruiting
Acute Myeloid Leukemia
Drug: Decitabine and Cedazuridine (ASTX727)
Drug: Venetoclax

Phase 1, Phase 2

Taiho Pharma
Taiho Pharma

Pittsburgh, Pennsylvania, United States and 33 other locations

This phase 2 study aims to confirm the efficacy seen in the prior phase 1 trial, and further contribute to this effort through the collection of leukemia...

Enrolling
Acute Myeloid Leukemia
Myelodysplastic Syndromes
Drug: Interferon gamma-1b
Biological: Donor Leukocyte Infusion (DLI)

Phase 2

Sawa Ito, MD

Pittsburgh, Pennsylvania, United States and 2 other locations

VEN+AZA alone for the treatment of participants with newly diagnosed Acute Myeloid Leukemia (AML) with a mutation...

Enrolling
Leukemia, Myeloid, Acute
Drug: Venetoclax (VEN)
Drug: Azacitidine (AZA)

Phase 3

Janssen (J&J Innovative Medicine)
Janssen (J&J Innovative Medicine)

Pittsburgh, Pennsylvania, United States and 252 other locations

Acute Myeloid Leukaemia (AML) is an aggressive and rare cancer of myeloid cells (a white blood cell responsible f...

Active, not recruiting
Acute Myeloid Leukemia (AML)
Drug: Placebo
Drug: Azacitidine

Phase 3

AbbVie
AbbVie

Pittsburgh, Pennsylvania, United States and 172 other locations

The purpose of the study is to characterize safety and tolerability of cusatuzumab in combination with various therapies used to treat acute ...

Active, not recruiting
Leukemia, Myeloid, Acute
Drug: Azacitidine
Drug: Venetoclax

Phase 1

OncoVerity

Pittsburgh, Pennsylvania, United States and 22 other locations

combination with chemotherapy in participants with newly diagnosed FMS-like tyrosine kinase 3 (FLT3)-internal tandem duplication (ITD) negative acute...

Active, not recruiting
Leukemia
Drug: Quizartinib
Drug: Placebo

Phase 3

Daiichi Sankyo
Daiichi Sankyo

Pittsburgh, Pennsylvania, United States and 285 other locations

monotherapy and in combination with azacitidine in participants with acute myeloid leukemia (AML) and myelodyspla...

Enrolling
Acute Myeloid Leukemia
Myelodysplastic Syndromes
Drug: BGB-11417
Drug: Azacitidine

Phase 1, Phase 2

BeOne Medicines

Pittsburgh, Pennsylvania, United States and 47 other locations

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