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The main objective of this study is to evaluate the efficacy of venetoclax in combination with azacitidine to improve Overall Survival (OS) in Acute...
Phase 3
Sevilla, Spain and 164 other locations
The purpose of the phase 1 portion (dose escalation) of the study will be to establish an optimally safe and biologically active recommended phase 2...
Phase 1, Phase 2
Sevilla, Spain and 24 other locations
This study enrolled 472 participants, aged 55 or older, with a diagnosis of de novo acute myeloid leukemia (AML) ...
Phase 3
Sevilla, Spain and 222 other locations
menin-MLL(KMT2A) inhibitor, in patients with relapsed or refractory acute myeloid leukemia (AML) as part of Phase....
Phase 1, Phase 2
Sevilla, Spain and 51 other locations
of standard chemotherapy plus quizartinib versus standard chemotherapy plus placebo in adult patients with newly diagnosed FLT3 wild-type Acute...
Phase 2
Sevilla, Spain and 44 other locations
A Phase 1 first-in-human dose-escalation and dose-expansion study of BMF-219, an oral covalent menin inhibitor, in adult patients with AML, ...
Phase 1
Sevilla, Spain and 40 other locations
monotherapy and in combination with azacitidine in participants with acute myeloid leukemia (AML) and myelodyspla...
Phase 1, Phase 2
Sevilla, Spain and 40 other locations
available therapy (BAT) on overall survival (OS) in subjects with acute myeloid leukemia (AML) who are in second ...
Phase 3
Sevilla, Spain and 72 other locations
efficacy and safety of the combination of oral quizartinib and FLAG-IDA chemotherapy schedule (FLAG-QUIDA regimen) in first relapsed/refractory AML...
Phase 1, Phase 2
Sevilla, Spain and 19 other locations
myeloid leukemia (AML) in transfusion-dependent participants with low or immediate-1 risk MDS that is relapsed/refractory...
Phase 2, Phase 3
Sevilla, Spain and 126 other locations
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