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The purpose of this study is to determine the clinical benefit of ASP2215 therapy in participants with FMS-like tyrosine kinase (FLT3) mutated acute...
Phase 3
Toronto, Ontario, Canada and 125 other locations
The main objective of this study is to evaluate the efficacy of venetoclax in combination with azacitidine to improve Overall Survival (OS) in Acute...
Phase 3
Toronto, Ontario, Canada and 164 other locations
allogeneic hematopoietic stem cell transplant (HCT), versus Conventional Care in patients with Active, Relapsed or Refractory Acute Myeloid...
Phase 3
Toronto, Ontario, Canada and 23 other locations
This trial will seek to extend the preliminary findings of efficacy of MBG453 in combination with hypomethylating agents (HMA) by evaluating MBG453 i...
Phase 2
Toronto, Ontario, Canada and 27 other locations
or young adults with a certain kind of blood cancer (FLT3-ITD AML) might be able to join this study if it has come back after remission or i...
Phase 1, Phase 2
Toronto, Ontario, Canada and 36 other locations
\[GO\]) improves survival of children/adolescents/young adults with acute myeloid leukemia (AML) in 1st relapse w...
Phase 3
Toronto, Ontario, Canada and 73 other locations
This is a clinical study for adult patients who have recently been diagnosed with acute myeloid leukemia or AML. ...
Phase 3
Toronto, Ontario, Canada and 110 other locations
This study will be conducted in two parts. Part 1 will be the Dose Confirmation portion to determine recommended Phase 3 dose (RPTD) of venetoclax in...
Phase 3
Toronto, Ontario, Canada and 160 other locations
with azacitidine versus with azacitidine alone in participants with acute myeloid leukemia (AML) with the isocitr...
Phase 1, Phase 2
Toronto, Ontario, Canada and 48 other locations
dose of BMS-986497 in participants with relapsed or refractory acute myeloid leukemia (AML) or myelodysplastic sy...
Phase 1
Toronto, Ontario, Canada and 10 other locations
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