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The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard of care (SOC) observation only.
Phase 3
Birmingham, Alabama, United States and 85 other locations
(CLDN18.2)-positive, human epidermal growth factor receptor 2 (HER2)-negative, gastric, gastroesophageal junction (GEJ), and esophageal adenocarcinoma...
Phase 3
Birmingham, Alabama, United States and 312 other locations
This study will help find the most suitable dose of ASP546C in people with gastric cancer, gastroesophageal junction (GEJ) cancer, pancreatic cancer,...
Phase 1, Phase 2
Birmingham, Alabama, United States and 21 other locations
nab-paclitaxel (G-nP) or gemcitabine, nab-paclitaxel (G-nP) and atezolizumab in previously untreated subjects with metastatic pancreatic ductal adenocarcinoma...
Phase 1
Birmingham, Alabama, United States
Zolbetuximab is being studied in people with cancer in and around the stomach or where the food pipe (esophagus) joins the stomach, called gastroesop...
Phase 3
Birmingham, Alabama, United States and 251 other locations
is to evaluate the efficacy and safety of standard chemotherapy with or without INCB161734 in participants with metastatic pancreatic ductal adenocarcinoma...
Phase 3
Birmingham, Alabama, United States and 229 other locations
The goal of this clinical study is to learn more about the study drug, TUB-040, including its safety, tolerability, pharmacokinetics, and preliminary...
Phase 1, Phase 2
Birmingham, Alabama, United States and 21 other locations
≥ 18 years with locally advanced or metastatic pancreatic ductal adenocarcinoma (PDAC), non-small cell lung cancer (NSCLC), HR+/HER2- ductal...
Phase 1
Birmingham, Alabama, United States and 28 other locations
Study to investigate the efficacy, safety and tolerability of systemic chemotherapy plus ponsegromab versus systemic chemotherapy plus placebo for th...
Phase 2, Phase 3
Birmingham, Alabama, United States and 230 other locations
PRE-ISPY Phase I/II (I-SPY-P1) is an open-label, multisite platform study with multiple ongoing drug regimen arms added by protocol amendment which i...
Phase 1, Phase 2
Birmingham, Alabama, United States and 9 other locations
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