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Find clinical trials for Adenocarcinoma in Charlotte, NC

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Related conditions:

Pancreatic Cancer
Colorectal Cancer
Stomach Cancer
Non-Small-Cell Lung Carcinoma
Prostatic Cancer
Neoplasm Metastasis
Esophageal Cancer

Adenocarcinoma trials near Charlotte, NC, USA:

Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

(CLDN18.2)-positive, human epidermal growth factor receptor 2 (HER2)-negative, gastric, gastroesophageal junction (GEJ), and esophageal adenocarcinoma...

Enrolling
Gastroesophageal Junction Adenocarcinoma
Esophageal Cancer
Drug: Sonesitatug vedotin
Drug: Nivolumab

Phase 3

AstraZeneca
AstraZeneca

Charlotte, North Carolina, United States and 312 other locations

New

of MC001 in adults with advanced or metastatic pancreatic ductal adenocarcinoma (PDAC) and other solid tumors that have relapsed or are refr...

Begins enrollment this month
Pancreatic Ductal Adenocarcinoma (PDAC)
Advanced Solid Tumor Cancer
Biological: MC001

Phase 1

Medicovestor, Inc

Huntersville, North Carolina, United States of America and 3 other locations

This is a first-in-human, Phase 1/2, open-label, study designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and prelimi...

Enrolling
Pancreatic Ductal Adenocarcinoma
Non Small Cell Lung Cancer
Drug: Pemetrexed
Drug: Carboplatin + Pemetrexed

Phase 1, Phase 2

Phanes Therapeutics

Huntersville, North Carolina, United States of America and 5 other locations

Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. The purpose of this study is to assess adverse events...

Enrolling
Pancreatic Ductal Adenocarcinoma
Gastroesophageal Junction Adenocarcinoma
Drug: ABBV-253

Phase 1

AbbVie
AbbVie

Huntersville, North Carolina, United States of America and 2 other locations

Zolbetuximab is being studied as a treatment for people with pancreatic cancer. Most people with pancreatic cancer have a protein called Claudin 18.2...

Active, not recruiting
Metastatic Pancreatic Adenocarcinoma
Metastatic Pancreatic Cancer
Drug: nab-paclitaxel
Drug: gemcitabine

Phase 2

Astellas
Astellas

Charlotte, North Carolina, United States and 135 other locations

This is an open-label, dose-escalation and dose-expansion study to determine the safety, tolerability, PK, pharmacodynamics, and preliminary efficacy...

Active, not recruiting
Solid Tumors
Drug: Palbociclib
Drug: Olaparib

Phase 1

Incyte
Incyte

Huntersville, North Carolina, United States and 40 other locations

a dose expansion phase to confirm the dose and combination with bevacizumab. Approximately 500 adult participants with NSCLC, gastroesophageal adenocarcinoma...

Active, not recruiting
Gastroesophageal Adenocarcinoma
Advanced Solid Tumors
Drug: ABBV-400
Drug: Trifluridine/Tipiracil

Phase 1

AbbVie
AbbVie

Huntersville, North Carolina, United States of America and 86 other locations

This is an open label, multi-center, multiple dose Phase 1 study to evaluate the safety, tolerability, MTD PK, and PD of TJ033721 (givastomig) in sub...

Enrolling
PDAC - Pancreatic Ductal Adenocarcinoma
Esophageal Adenocarcinoma
Drug: TJ033721 (givastomig), durvalumab, chemotherapy
Drug: TJ033721 (givastomig)

Phase 1

I-Mab Biopharma

Huntersville, North Carolina, United States of America and 20 other locations

This study is to evaluate the safety and tolerability of RMC-9805 as monotherapy and in combination with RMC-6236 in adults with KRAS G12D-mutant sol...

Enrolling
Pancreatic Ductal Adenocarcinoma (PDAC)
Non-small Cell Lung Cancer (NSCLC)
Drug: RMC-6236
Drug: RMC-9805

Phase 1

Revolution Medicines
Revolution Medicines

Huntersville, North Carolina, United States of America and 16 other locations

This is a study to evaluate the safety and potential anti-tumor activity of an investigational agent called ARV-806 in Adults with Advanced Cancer ha...

Active, not recruiting
Advanced Solid Cancer
KRAS G12D Mutation
Drug: ARV-806

Phase 1, Phase 2

Arvinas
Arvinas

Huntersville, North Carolina, United States and 13 other locations

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