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(CLDN18.2)-positive, human epidermal growth factor receptor 2 (HER2)-negative, gastric, gastroesophageal junction (GEJ), and esophageal adenocarcinoma...
Phase 3
Charlotte, North Carolina, United States and 312 other locations
of MC001 in adults with advanced or metastatic pancreatic ductal adenocarcinoma (PDAC) and other solid tumors that have relapsed or are refr...
Phase 1
Huntersville, North Carolina, United States of America and 3 other locations
This is a first-in-human, Phase 1/2, open-label, study designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and prelimi...
Phase 1, Phase 2
Huntersville, North Carolina, United States of America and 5 other locations
Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. The purpose of this study is to assess adverse events...
Phase 1
Huntersville, North Carolina, United States of America and 2 other locations
Zolbetuximab is being studied as a treatment for people with pancreatic cancer. Most people with pancreatic cancer have a protein called Claudin 18.2...
Phase 2
Charlotte, North Carolina, United States and 135 other locations
This is an open-label, dose-escalation and dose-expansion study to determine the safety, tolerability, PK, pharmacodynamics, and preliminary efficacy...
Phase 1
Huntersville, North Carolina, United States and 40 other locations
a dose expansion phase to confirm the dose and combination with bevacizumab. Approximately 500 adult participants with NSCLC, gastroesophageal adenocarcinoma...
Phase 1
Huntersville, North Carolina, United States of America and 86 other locations
This is an open label, multi-center, multiple dose Phase 1 study to evaluate the safety, tolerability, MTD PK, and PD of TJ033721 (givastomig) in sub...
Phase 1
Huntersville, North Carolina, United States of America and 20 other locations
This study is to evaluate the safety and tolerability of RMC-9805 as monotherapy and in combination with RMC-6236 in adults with KRAS G12D-mutant sol...
Phase 1
Huntersville, North Carolina, United States of America and 16 other locations
This is a study to evaluate the safety and potential anti-tumor activity of an investigational agent called ARV-806 in Adults with Advanced Cancer ha...
Phase 1, Phase 2
Huntersville, North Carolina, United States and 13 other locations
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