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The purpose of this study is to evaluate the efficacy of an investigational RAS(ON) inhibitor administered in combination with chemotherapy compared...
Phase 3
Chicago, Illinois, United States and 3 other locations
(TPC) in participants with advanced/metastatic gastroesophageal adenocarcinoma. The primary hypothesis of this study is sacituzumab tirumote...
Phase 3
Chicago, Illinois, United States and 168 other locations
The objective of this study is to assess safety and efficacy of BA3182 in Advanced Adenocarcinoma...
Phase 1
Chicago, Illinois, United States and 8 other locations
(CLDN18.2)-positive, human epidermal growth factor receptor 2 (HER2)-negative, gastric, gastroesophageal junction (GEJ), and esophageal adenocarcinoma...
Phase 3
Chicago, Illinois, United States and 284 other locations
The purpose of this study is to evaluate the safety and efficacy of atebimetinib in combination with modified GnP compared with SOC GnP alone.
Phase 3
Chicago, Illinois, United States and 22 other locations
The study population is advanced gastric, gastroesophageal, and esophageal adenocarcinoma participants who have failed upfront standard of c...
Phase 1, Phase 2
Chicago, Illinois, United States and 7 other locations
drug being developed for the treatment of pancreatic ductal adenocarcinoma (PDAC). This study will be divided into two phases, with the firs...
Phase 2, Phase 3
Zion, Illinois, United States and 17 other locations
The purpose of this study is to compare overall survival of quemliclustat, nab-paclitaxel and gemcitabine versus placebo, nab-paclitaxel and gemcitab...
Phase 3
Chicago, Illinois, United States and 118 other locations
The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard(s) of care (SOC) treatment.
Phase 3
Chicago, Illinois, United States and 59 other locations
with chemotherapy in participants with previously untreated advanced or metastatic gastric, gastroesophageal junction, or esophageal adenocarcinoma...
Phase 2, Phase 3
Chicago, Illinois, United States and 161 other locations
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