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The objective of this study is to assess safety and efficacy of BA3182 in Advanced Adenocarcinoma...
Phase 1
Cincinnati, Ohio, United States and 8 other locations
The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard(s) of care (SOC) treatment.
Phase 3
Cincinnati, Ohio, United States and 59 other locations
after complete surgical resection (R0) in participants with Stage I adenocarcinoma NSCLC who are ctDNA-positive, as determined by the Sponso...
Phase 3
Cincinnati, Ohio, United States and 224 other locations
This is an open label Phase 2 study to evaluate the efficacy and safety of ACR-368 as monotherapy or with ultra-low dose gemcitabine (ULDG) sensitiza...
Phase 2
Cincinnati, Ohio, United States and 68 other locations
and safety of AZD0901 compared to Investigator's choice of therapy as 2L+ treatment for participants with advanced or metastatic gastric or GEJ adenocarcinoma...
Phase 3
Cincinnati, Ohio, United States and 185 other locations
mFOLFIRINOX alone in participants with resected pancreatic ductal adenocarcinoma (PDAC) who have not received prior systemic anti-cancer tre...
Phase 2
Cincinnati, Ohio, United States and 88 other locations
Zolbetuximab is being studied in people with cancer in and around the stomach or where the food pipe (esophagus) joins the stomach, called gastroesop...
Phase 3
Middletown, Ohio, United States and 219 other locations
The purpose of this multicentric, open label trial (NAPISTAR 1-01) is to evaluate the safety/tolerability, pharmacokinetics and preliminary efficacy...
Phase 1, Phase 2
Cincinnati, Ohio, United States and 11 other locations
The purpose of this platform study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of novel RAS(ON...
Phase 1, Phase 2
Cincinnati, Ohio, United States and 29 other locations
Evaluate the safety and tolerability of RMC-6236 in adults with specific RAS mutant advanced solid tumors.
Phase 1
Cincinnati, Ohio, United States and 15 other locations
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