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The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard of care (SOC) observation only.
Phase 3
Indianapolis, Indiana, United States and 14 other locations
resectable or borderline resectable, previously untreated pancreatic adenocarcinoma. The primary objective of this study is to investigate t...
Phase 2
Indianapolis, Indiana, United States and 3 other locations
(CLDN18.2)-positive, human epidermal growth factor receptor 2 (HER2)-negative, gastric, gastroesophageal junction (GEJ), and esophageal adenocarcinoma...
Phase 3
Indianapolis, Indiana, United States and 257 other locations
The purpose of this study is to compare overall survival of quemliclustat, nab-paclitaxel and gemcitabine versus placebo, nab-paclitaxel and gemcitab...
Phase 3
Indianapolis, Indiana, United States and 124 other locations
and capecitabine monotherapy in patients with metastatic pancreatic adenocarcinoma whose disease has not progressed on a first line fluoropy...
Phase 1, Phase 2
Indianapolis, Indiana, United States and 15 other locations
in individuals with pathologically confirmed pancreatic ductal adenocarcinoma. Following screening, using a standardized administration prot...
Phase 3
Indianapolis, Indiana, United States and 9 other locations
Zolbetuximab is being studied in people with cancer in and around the stomach or where the food pipe (esophagus) joins the stomach, called gastroesop...
Phase 3
Indianapolis, Indiana, United States and 199 other locations
This is an open label Phase 2 study to evaluate the efficacy and safety of ACR-368 as monotherapy or with ultra-low dose gemcitabine (ULDG) sensitiza...
Phase 2
Indianapolis, Indiana, United States and 89 other locations
is to evaluate the efficacy and safety of standard chemotherapy with or without INCB161734 in participants with metastatic pancreatic ductal adenocarcinoma...
Phase 3
Indianapolis, Indiana, United States and 211 other locations
mFOLFIRINOX alone in participants with resected pancreatic ductal adenocarcinoma (PDAC) who have not received prior systemic anti-cancer tre...
Phase 2
Indianapolis, Indiana, United States and 89 other locations
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