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resectable or borderline resectable, previously untreated pancreatic adenocarcinoma. The primary objective of this study is to investigate t...
Phase 2
Indianapolis, Indiana, United States and 3 other locations
and capecitabine monotherapy in patients with metastatic pancreatic adenocarcinoma whose disease has not progressed on a first line fluoropy...
Phase 1, Phase 2
Indianapolis, Indiana, United States and 18 other locations
Patients can be prescreened for the study at the time of diagnosis of locally advanced or metastatic disease by determining presence of LOH high stat...
Phase 2
Indianapolis, Indiana, United States and 3 other locations
The purpose of this study is to determine the Objective Response Rate (ORR) of zolbetuzimab as a single agent as assessed by an independent central r...
Phase 2
Indianapolis, Indiana, United States and 25 other locations
a dose expansion phase to confirm the dose and combination with bevacizumab. Approximately 500 adult participants with NSCLC, gastroesophageal adenocarcinoma...
Phase 1
Indianapolis, Indiana, United States and 79 other locations
This is a first-in-human phase I/II study to examine the safety, tolerability and preliminary efficacy of VLS-1488 in subjects with advanced cancers.
Phase 1, Phase 2
Indianapolis, Indiana, United States and 9 other locations
The main objective of this study is to compare efficacy of bemarituzumab combined with oxaliplatin, leucovorin, and 5-fluorouracil (5-FU) (mFOLFOX6)...
Phase 3
Indianapolis, Indiana, United States and 300 other locations
To investigate the combination of nivolumab and ipilimumab with panitumumab in subjects with unresectable, refractory, KRAS/NRAS/BRAF wild-type, micr...
Phase 2
Indianapolis, Indiana, United States and 4 other locations
This study looked at how effective the study drug (tepotinib) was at stopping the growth and spread of lung cancer. This study also measures a number...
Phase 2
Indianapolis, Indiana, United States and 176 other locations
The primary objectives of this study are to observe the safety and tolerability of bemarituzumab and to evaluate preliminary antitumor activity.
Phase 1, Phase 2
Indianapolis, Indiana, United States and 109 other locations
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