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Find clinical trials for Adenocarcinoma in Indianapolis, IN

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Related conditions:

Carcinoma
Cancer
Pancreatic Cancer
Colorectal Cancer
Stomach Cancer
Prostatic Cancer
Esophageal Cancer

Adenocarcinoma trials near Indianapolis, IN, USA:

A Study of the Safety and Activity of Liposomal Irinotecan in Combination With the 5-FU and Oxaliplatin in the Preoperative Treatment of Pancreatic Adenocarcinoma

resectable or borderline resectable, previously untreated pancreatic adenocarcinoma. The primary objective of this study is to investigate t...

Active, not recruiting
Pancreatic Adenocarcinoma
Drug: Liposomal Irinotecan
Drug: FOLFOX regimen

Phase 2

University of Florida
University of Florida

Indianapolis, Indiana, United States and 3 other locations

and capecitabine monotherapy in patients with metastatic pancreatic adenocarcinoma whose disease has not progressed on a first line fluoropy...

Enrolling
Metastatic Pancreatic Adenocarcinoma
Drug: Capecitabine
Drug: Ivaltinostat

Phase 1, Phase 2

CG Pharmaceuticals

Indianapolis, Indiana, United States and 19 other locations

mFOLFIRINOX alone in participants with resected pancreatic ductal adenocarcinoma (PDAC) who have not received prior systemic anti-cancer tre...

Enrolling
Adenocarcinoma, Pancreatic Ductal
Drug: mFOLFIRINOX
Drug: Autogene cevumeran

Phase 2

Genentech
Genentech

Indianapolis, Indiana, United States and 38 other locations

The purpose of this study is to determine the Objective Response Rate (ORR) of zolbetuzimab as a single agent as assessed by an independent central r...

Enrolling
Pharmacokinetics of Oxaliplatin
Pharmacokinetics of Zolbetuximab
Drug: folinic acid
Drug: fluorouracil

Phase 2

Astellas
Astellas

Indianapolis, Indiana, United States and 25 other locations

a dose expansion phase to confirm the dose and combination with bevacizumab. Approximately 500 adult participants with NSCLC, gastroesophageal adenocarcinoma...

Enrolling
Gastroesophageal Adenocarcinoma
Advanced Solid Tumors
Drug: ABBV-400
Drug: Trifluridine/Tipiracil

Phase 1

AbbVie
AbbVie

Indianapolis, Indiana, United States and 81 other locations

This is a first-in-human phase I/II study to examine the safety, tolerability and preliminary efficacy of VLS-1488 in subjects with advanced cancers.

Enrolling
High Grade Serous Adenocarcinoma of Ovary
Gastric Adenocarcinoma
Drug: VLS-1488

Phase 1, Phase 2

Volastra Therapeutics

Indianapolis, Indiana, United States and 9 other locations

The main objective of this study is to compare efficacy of bemarituzumab combined with oxaliplatin, leucovorin, and 5-fluorouracil (5-FU) (mFOLFOX6)...

Active, not recruiting
Gastroesophageal Junction Adenocarcinoma
Gastric Cancer
Drug: Bemarituzumab
Drug: mFOLFOX6

Phase 3

Amgen
Amgen

Indianapolis, Indiana, United States and 300 other locations

This is a Phase 1 study of GV20-0251 being developed for the treatment of participants with advanced solid tumors, who are refractory to approved the...

Enrolling
Adenocarcinoma of the Colon
Adenocarcinoma of the Rectum
Drug: GV20-0251

Phase 1

GV20 Therapeutics

Indianapolis, Indiana, United States and 12 other locations

To investigate the combination of nivolumab and ipilimumab with panitumumab in subjects with unresectable, refractory, KRAS/NRAS/BRAF wild-type, micr...

Active, not recruiting
Colon Cancer
Drug: Nivolumab
Drug: Ipilimumab

Phase 2

UNC Lineberger Comprehensive Cancer Center
UNC Lineberger Comprehensive Cancer Center

Indianapolis, Indiana, United States and 4 other locations

This study looked at how effective the study drug (tepotinib) was at stopping the growth and spread of lung cancer. This study also measures a number...

Active, not recruiting
Lung Adenocarcinoma Stage IIIB/IV
Advanced (Stage IIIB/IV) Non-small Cell Lung Cancer (NSCLC) With MET Exon 14 (METex14) Skipping Alterations or MET Amplification
Drug: Tepotinib

Phase 2

Merck KGaA (EMD Serono)
Merck KGaA (EMD Serono)

Indianapolis, Indiana, United States and 176 other locations

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