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Find clinical trials for Adenocarcinoma in Orlando, FL

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Cancer
Carcinoma
Pancreatic Cancer
Colorectal Cancer
Stomach Cancer
Esophageal Cancer
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Adenocarcinoma trials near Orlando, FL, USA:

A Study to Evaluate Sacituzumab Tirumotecan (MK-2870) in Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-2870-015) (TroFuse-015)

(TPC) in participants with advanced/metastatic gastroesophageal adenocarcinoma. The primary hypothesis of this study is sacituzumab tirumote...

Enrolling
Gastroesophageal Cancer
Drug: Rescue medication
Drug: Supportive care measures

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Orlando, Florida, United States and 101 other locations

resectable or borderline resectable, previously untreated pancreatic adenocarcinoma. The primary objective of this study is to investigate t...

Active, not recruiting
Pancreatic Adenocarcinoma
Drug: Liposomal Irinotecan
Drug: FOLFOX regimen

Phase 2

University of Florida
University of Florida

Orlando, Florida, United States and 3 other locations

as First-Line or Second-Line Therapy in Adult Patients with Inoperable, Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma...

Active, not recruiting
Gastric Adenocarcinoma
Gastric Cancer
Drug: Tislelizumab 200mg
Drug: DKN-01 400mg

Phase 2

Leap Therapeutics

Orlando, Florida, United States and 47 other locations

The goal of this clinical trial is to test an experimental treatment (immunotherapy) in pancreatic cancer patients. The main research objectives are:...

Enrolling
Pancreatic Ductal Adenocarcinoma
Drug: ATP150
Drug: Ezabenlimab

Phase 1

Amal Therapeutics

Orlando, Florida, United States and 14 other locations

Status recently updated

after complete surgical resection (R0) in participants with Stage I adenocarcinoma NSCLC who are ctDNA-positive, as determined by the Sponso...

Not yet enrolling
Enrolling
Non-small Cell Lung Cancer
Drug: Pemetrexed
Drug: Rilvegostomig

Phase 3

AstraZeneca
AstraZeneca

Orlando, Florida, United States and 186 other locations

and safety of AZD0901 compared to Investigator's choice of therapy as 2L+ treatment for participants with advanced or metastatic gastric or GEJ adenocarcinoma...

Enrolling
Gastroesophageal Junction Cancer
Gastric Cancer
Drug: AZD0901
Drug: Docetaxel

Phase 3

AstraZeneca
AstraZeneca

Orlando, Florida, United States and 165 other locations

unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma. Why is this study being done? SPOTLIGHT is a new clinical st...

Active, not recruiting
Metastatic Gastric Adenocarcinoma or Cancer
Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer
Drug: fluorouracil
Drug: zolbetuximab

Phase 3

Astellas
Astellas

Orlando, Florida, United States and 219 other locations

A Phase 1/2 study of MRTX1133 in solid tumors harboring a KRAS G12D mutation.

Enrolling
Pancreatic Adenocarcinoma
Solid Tumor
Drug: MRTX1133

Phase 1, Phase 2

Mirati Therapeutics
Mirati Therapeutics

Lady Lake, Florida, United States and 15 other locations

This is a Phase 1/2, open-label, multicenter, study of the safety, tolerability, PK, PD, and anti-tumor activity of MRTX1719 patients with advanced,...

Enrolling
Pancreatic Adenocarcinoma
Solid Tumor
Drug: MRTX1719

Phase 1, Phase 2

Mirati Therapeutics
Mirati Therapeutics

Orlando, Florida, United States and 20 other locations

A Phase 1/2 study to evaluate the safety and efficacy of ARV-766 given by mouth alone or in combination with abiraterone in men with metastatic prost...

Enrolling
Prostate Cancer Metastatic
Drug: ARV-766 + Abiraterone Part C&D
Drug: ARV-766 Part A&B

Phase 1, Phase 2

Arvinas
Arvinas

Lake Mary, Florida, United States and 22 other locations

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