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Find clinical trials for Adenocarcinoma in Rochester, MN

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Esophageal Cancer
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Adenocarcinoma trials near Rochester, MN, USA:

Recently updated

Onvansertib in Combination with Nanoliposomal Irinotecan, Leucovorin, and Fluorouracil for Second-Line Treatment of Participants with Metastatic Pancreatic Ductal Adenocarcinoma

(nal-IRI), leucovorin, and fluorouracil (5-FU) for treatment of participants with histologically confirmed metastatic pancreatic ductal adenocarcinoma...

Active, not recruiting
Pancreatic Ductal Adenocarcinoma
Drug: Nanoliposomal irinotecan
Drug: Leucovorin

Phase 2

Cardiff Oncology

Rochester, Minnesota, United States and 5 other locations

Cohort 1 \[CLOSED\] Study treatment involves two segments: (1) Induction Immunotherapy segment with pembrolizumab monotherapy every 3 weeks until irR...

Enrolling
Adenocarcinoma
Gastric Cancer
Drug: Ramucirumab
Drug: Paclitaxel

Phase 2

Harry H Yoon

Rochester, Minnesota, United States and 1 other location

Status recently updated

after complete surgical resection (R0) in participants with Stage I adenocarcinoma NSCLC who are ctDNA-positive, as determined by the Sponso...

Not yet enrolling
Enrolling
Non-small Cell Lung Cancer
Drug: Pemetrexed
Drug: Rilvegostomig

Phase 3

AstraZeneca
AstraZeneca

Rochester, Minnesota, United States and 186 other locations

This research is designed to determine if experimental treatment with AZD5863, a T cell-engaging bispecific antibody that targets Claudin 18.2 (CLDN1...

Enrolling
Esophageal Adenocarcinoma
Pancreatic Ductal Adenocarcinoma
Drug: AZD5863

Phase 1, Phase 2

AstraZeneca
AstraZeneca

Rochester, Minnesota, United States and 24 other locations

Locations recently updated

The purpose of this study is to determine the response rate to the combination of folate receptor alpha dendritic cells (FRaDCs) plus pembrolizumab i...

Enrolling
Recurrent Fallopian Tube Clear Cell Adenocarcinoma
Recurrent Fallopian Tube Endometrioid Adenocarcinoma
Procedure: Pheresis
Procedure: Magnetic Resonance Imaging

Phase 1, Phase 2

Mayo Clinic
Mayo Clinic

Rochester, Minnesota, United States and 2 other locations

This trial studies tucatinib to find out if it is safe when given with trastuzumab and other anti-cancer drugs (pembrolizumab, FOLFOX, and CAPOX). It...

Active, not recruiting
Esophageal Adenocarcinoma
Gastric Adenocarcinoma
Drug: oxaliplatin
Drug: trastuzumab

Phase 1, Phase 2

Seagen
Seagen

Rochester, Minnesota, United States and 21 other locations

This is a Phase 1/2 study to assess the safety and efficacy of ELI-002 7P immunotherapy (a lipid-conjugated immune-stimulatory oligonucleotide \[Amph...

Enrolling
Pancreatic Ductal Adenocarcinoma
KRAS G12V
Drug: ELI-002 7P

Phase 1, Phase 2

Elicio Therapeutics
Elicio Therapeutics

Rochester, Minnesota, United States and 27 other locations

The purpose of this study is to look at the efficacy and safety of Irinotecan liposome injection in combination with other approved drugs used for ca...

Active, not recruiting
Metastatic Adenocarcinoma of the Pancreas
Drug: Leucovorin
Drug: Gemcitabine

Phase 3

Ipsen
Ipsen

Rochester, Minnesota, United States and 199 other locations

This is a Phase 1/2, open-label, multicenter, study of the safety, tolerability, PK, PD, and anti-tumor activity of MRTX1719 patients with advanced,...

Enrolling
Pancreatic Adenocarcinoma
Solid Tumor
Drug: MRTX1719

Phase 1, Phase 2

Mirati Therapeutics
Mirati Therapeutics

Rochester, Minnesota, United States and 20 other locations

A Phase Ib/II, open label, multi-center, randomized study designed to assess the safety, tolerability, pharmacokinetics and preliminary anti-tumor ac...

Active, not recruiting
Gastric Adenocarcinoma or Gastroesophageal Junction Adenocarcinoma or Esophageal Carcinoma
Drug: Cobimetinib
Biological: Ramucirumab

Phase 1, Phase 2

Roche
Roche

Rochester, Minnesota, United States and 35 other locations

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