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Find clinical trials for Adenocarcinoma in Sevilla, AN

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Carcinoma
Cancer
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Colorectal Cancer
Stomach Cancer
Esophageal Cancer
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Adenocarcinoma trials near Sevilla, AN, ESP:

Safety and Efficacy of Mitazalimab in Combination with Chemotherapy in Pancreatic Cancer Patients (OPTIMIZE-1)

Phase 1b/2 study to assess the safety and efficacy of mitazalimab in combination with chemotherapy in patients with metastatic pancreatic ductal adenocarcinoma...

Active, not recruiting
Metastatic Pancreatic Ductal Adenocarcinoma
Biological: CD40 agonist mitazalimab in combination with chemotherapy

Phase 1, Phase 2

Alligator Bioscience

Sevilla, Spain and 13 other locations

and safety of AZD0901 compared to Investigator's choice of therapy as 2L+ treatment for participants with advanced or metastatic gastric or GEJ adenocarcinoma...

Enrolling
Gastroesophageal Junction Cancer
Gastric Cancer
Drug: AZD0901
Drug: Docetaxel

Phase 3

AstraZeneca
AstraZeneca

Sevilla, Spain and 176 other locations

unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma. Why is this study being done? SPOTLIGHT is a new clinical st...

Active, not recruiting
Metastatic Gastric Adenocarcinoma or Cancer
Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer
Drug: fluorouracil
Drug: zolbetuximab

Phase 3

Astellas
Astellas

Sevilla, Spain and 219 other locations

This study is being done to find out if zanidatamab, when given with chemotherapy plus or minus tislelizumab, is safe and works better than trastuzum...

Enrolling
Gastroesophageal Adenocarcinoma
Esophageal Adenocarcinoma
Drug: Tislelizumab
Drug: Capecitabine

Phase 3

Jazz Pharmaceuticals
Jazz Pharmaceuticals

Sevilla, Spain and 313 other locations

Locations recently updated

This study is open to adults aged 18 years and older with different types of HER2+ cancer that has spread and cannot be removed by surgery. People ca...

Enrolling
Metastatic Gastric Adenocarcinoma
Esophageal Adenocarcinoma
Drug: Trastuzumab emtansine
Drug: Zongertinib

Phase 1, Phase 2

Boehringer Ingelheim
Boehringer Ingelheim

Sevilla, Spain and 44 other locations

A phase IIb, open-label, randomized study of Nab-Paclitaxel and Gemcitabine and plus/minus VCN-01 in Patients with Metastatic Pancreatic Cancer

Active, not recruiting
Pancreatic Adenocarcinoma
Metastatic
Genetic: VCN-01
Drug: Gemcitabine

Phase 2

Theriva Biologics

Sevilla, Andalucia, Spain and 16 other locations

in subjects previously untreated for metastatic pancreatic ductal adenocarcinoma (PDA), including subjects who have received prior neoadjuva...

Enrolling
Pancreatic Ductal Adenocarcinoma
Pancreatic Cancer Metastatic
Drug: Gemcitabine
Drug: Nab-paclitaxel

Phase 2, Phase 3

Panbela Therapeutics

Sevilla, Spain and 91 other locations

This is an open-label, parallel group, non-randomized, multicenter phase II study to evaluate the efficacy of spartalizumab (cohorts 1 and 2) and tis...

Active, not recruiting
Pancreatic Adenocarcinoma
Prostate Adenocarcinoma
Drug: Spartalizumab
Drug: Tislelizumab

Phase 2

SOLTI

Sevilla, Spain and 12 other locations

Status recently updated

a dose expansion phase to confirm the dose and combination with bevacizumab. Approximately 500 adult participants with NSCLC, gastroesophageal adenocarcinoma...

Enrolling
Active, not recruiting
Gastroesophageal Adenocarcinoma
Advanced Solid Tumors
Drug: ABBV-400
Drug: Trifluridine/Tipiracil

Phase 1

AbbVie
AbbVie

Sevilla, Sevilla, Spain and 84 other locations

T-DXd (Arm A) compared to trastuzumab, chemotherapy, and pembrolizumab (Arm B) in HER2-positive locally advanced or metastatic gastric or GEJ adenocarcinoma...

Begins enrollment in 1 month
Gastroesophageal Junction Adenocarcinoma
HER2-positive Gastric Cancer
Drug: Capecitabine
Drug: Trastuzumab deruxtecan

Phase 3

AstraZeneca
AstraZeneca

Sevilla, Spain and 149 other locations

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