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This is a randomized, double-blind, sham-controlled, adaptive-design pivotal study of sensory stimulation in subjects with mild to moderate Alzheimer's...
Farmington, Michigan, United States and 67 other locations
is superior to placebo on change from baseline of the Preclinical Alzheimer Cognitive Composite 5 (PACC5) at 216 weeks of treatment (A45 Tri...
Phase 3
Ann Arbor, Michigan, United States and 111 other locations
Alzheimer's disease (AD) is a progressive, irreversible neurological disorder and is the most common cause of dementia in the elder...
Phase 2
Farmington Hills, Michigan, United States of America and 36 other locations
be from 2 clinical subgroups: mild cognitive impairment (MCI) due to Alzheimer's disease (AD) or mild Alzheimer's disease...
Phase 2
Ann Arbor, Michigan, United States and 168 other locations
This is an open-label extension for a multicenter, randomized, double-blind, sham-controlled, adaptive design pivotal study.Participants who complete...
Farmington, Michigan, United States and 52 other locations
This study will evaluate the long-term safety and efficacy of AXS-05 in subjects with Alzheimer's disease (AD) agitation....
Phase 3
Rochester Hills, Michigan, United States and 39 other locations
female subjects who are aged 55 to 90 years and have mild to severe Alzheimer's Disease (AD) with moderate to severe psychosis rela...
Phase 3
Rochester Hills, Michigan, United States and 63 other locations
frequency and severity of ARIA-E in adults with early symptomatic Alzheimer's disease (AD) and explore participant characteristics ...
Phase 3
Farmington Hills, Michigan, United States of America and 44 other locations
randomized study to evaluate the efficacy and safety of AXS-05 compared to placebo for the treatment of agitation associated with Alzheimer's...
Phase 3
Rochester Hills, Michigan, United States and 52 other locations
as measured by changes in the Clinical Dementia Rating Scale Sum of Boxes (CDR-SB) score as compared with placebo in participants with early Alzheimer's...
Phase 3
Farmington Hills, Michigan, United States and 210 other locations
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