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Find clinical trials for Alzheimer's Disease in Columbus, OH

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Related conditions:

Alzheimer Disease
Dementia
Cognitive Dysfunction
Mental Disorders
Brain Diseases
Neurodegenerative Diseases
Psychomotor Agitation

Alzheimer's Disease trials near Columbus, OH, USA:

A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (Hope Study, CA-0011)

This is a randomized, double-blind, sham-controlled, adaptive-design pivotal study of sensory stimulation in subjects with mild to moderate Alzheimer's...

Enrolling
Alzheimer Disease 6
Dementia of Alzheimer Type
Device: Sensory Stimulation System (GS120) - Sham
Device: Sensory Stimulation System (GS120) - Active
Cognito Therapeutics
Cognito Therapeutics

Columbus, Ohio, United States and 67 other locations

the safety and efficacy of the ExAblate Model 4000 Type 2.0 System as a tool to disrupt the blood-brain barrier (BBB) in patients with probable Alzheimer's...

Enrolling
Alzheimer Disease
Device: Blood Brain Barrier (BBB) Disruption
InSightec
InSightec

Columbus, Ohio, United States and 8 other locations

double-blind, placebo-controlled, parallel group 36 week multicenter Phase 2 study of two doses of CT1812 in adults with mild to moderate Alzheimer's...

Active, not recruiting
Mild to Moderate Alzheimer's Disease
Drug: CT1812
Drug: Placebo

Phase 2

Cognition Therapeutics
Cognition Therapeutics

Columbus, Ohio, United States and 31 other locations

is superior to placebo on change from baseline of the Preclinical Alzheimer Cognitive Composite 5 (PACC5) at 216 weeks of treatment (A45 Tri...

Enrolling
Preclinical Alzheimer's Disease
Early Preclinical Alzheimer's Disease
Drug: Lecanemab
Drug: Placebo

Phase 3

Eisai
Eisai

Columbus, Ohio, United States and 111 other locations

This study will be conducted to evaluate the efficacy of lecanemab in participants with early Alzheimer's disease (EAD) by determin...

Active, not recruiting
Early Alzheimer's Disease
Drug: Lecanemab
Drug: Placebo

Phase 3

Eisai
Eisai

Columbus, Ohio, United States and 246 other locations

This is a 96-week extension study of open-label simufilam 100 mg b.i.d. for mild-to-moderate Alzheimer's disease subjects who compl...

Active, not recruiting
Alzheimer's Disease
Drug: simufilam

Phase 2

Cassava Sciences

Columbus, Ohio, United States and 10 other locations

This is a phase 2A multi-center, randomized, double blind, placebo-controlled, parallel group study of varoglutamstat, with a stage gate to phase 2B....

Enrolling
Alzheimer Disease
Other: Placebo
Drug: PQ912

Phase 2

Vivoryon Therapeutics

Columbus, Ohio, United States and 21 other locations

This is an open-label extension for a multicenter, randomized, double-blind, sham-controlled, adaptive design pivotal study.Participants who complete...

Invitation-only
Alzheimer Disease
Dementia of Alzheimer Type
Device: Sensory Stimulation System (GS120) - Active
Cognito Therapeutics
Cognito Therapeutics

Columbus, Ohio, United States and 52 other locations

A 76-week safety and efficacy study of simufilam (PTI-125) given twice daily to participants with mild-to-moderate Alzheimer's disease...

Active, not recruiting
Alzheimer Disease
Drug: Placebo
Drug: Simufilam

Phase 3

Cassava Sciences

Columbus, Ohio, United States and 89 other locations

The primary purpose of this study is to evaluate the effect of JNJ-63733657 versus placebo on clinical decline as measured by the Integrated Alzheimer's...

Active, not recruiting
Alzheimer Disease
Cognitive Dysfunction
Drug: Placebo
Drug: JNJ-63733657

Phase 2

Janssen (J&J Innovative Medicine)

Columbus, Ohio, United States and 122 other locations

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