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Find clinical trials for Alzheimer's Disease in Columbus, OH

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Related conditions:

Alzheimer Disease
Dementia
Cognitive Dysfunction
Mental Disorders
Brain Diseases
Nervous System Diseases
Parkinson Disease

Alzheimer's Disease trials near Columbus, OH, USA:

A Study to Evaluate the Safety and Efficacy of CT1812 in Early Alzheimer's Disease

designed to evaluate the efficacy, safety, and tolerability of two doses of CT1812 compared to placebo in participants diagnosed with early Alzheimer's...

Active, not recruiting
Early Alzheimer's Disease
Drug: Placebo
Drug: CT1812

Phase 2

Cognition Therapeutics
Cognition Therapeutics

Columbus, Ohio, United States and 50 other locations

the safety and efficacy of the ExAblate Model 4000 Type 2.0 System as a tool to disrupt the blood-brain barrier (BBB) in patients with probable Alzheimer's...

Enrolling
Alzheimer Disease
Device: Blood Brain Barrier (BBB) Disruption
InSightec
InSightec

Columbus, Ohio, United States and 9 other locations

This is a multicentre, randomized, double-blind, placebo-controlled, parallel group Phase II study to evaluate the efficacy and safety of VHB937 in p...

Enrolling
Alzheimer's Disease
Biological: VHB937
Other: Placebo

Phase 2

Novartis
Novartis

Columbus, Ohio, United States and 49 other locations

or Sham investigational device, Spectris™ AD, for 60 minutes daily for approximately 12 months. Efficacy will be measured using the Integrated Alzheimer's...

Active, not recruiting
Alzheimer Disease 6
Dementia of Alzheimer Type
Device: Spectris™ AD - Active
Device: Spectris™ AD - Sham
Cognito Therapeutics
Cognito Therapeutics

Columbus, Ohio, United States and 68 other locations

is superior to placebo on change from baseline of the Preclinical Alzheimer Cognitive Composite 5 (PACC5) at 216 weeks of treatment (A45 Tri...

Active, not recruiting
Preclinical Alzheimer's Disease
Early Preclinical Alzheimer's Disease
Drug: Lecanemab
Drug: Placebo

Phase 3

Eisai
Eisai

Columbus, Ohio, United States and 108 other locations

and efficacy of ONO-2020 in participants with mild to moderate Alzheimer's disease (AD). This study aims to determine whether admin ...

Active, not recruiting
Alzheimer Disease
Drug: Placebo
Drug: ONO-2020

Phase 2

Ono Pharmaceuticals
Ono Pharmaceuticals

Columbus, Ohio, United States and 96 other locations

Locations recently updated

The purpose of this study is to evaluate the efficacy and safety of KarXT + KarX-EC for cognitive impairment in Alzheimer's Disease...

Enrolling
Alzheimer's Disease
Other: Placebo
Drug: KarXT

Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Columbus, Ohio, United States and 104 other locations

This study will be conducted to evaluate the efficacy of lecanemab in participants with early Alzheimer's disease (EAD) by determin...

Active, not recruiting
Early Alzheimer's Disease
Drug: Lecanemab SC
Drug: Placebo

Phase 3

Eisai
Eisai

Columbus, Ohio, United States and 246 other locations

The purpose of this study is to evaluate the safety and efficacy of KarXT in adult participants with mild to severe Alzheimer's Disease...

Enrolling
Alzheimer Disease
Drug: Placebo
Drug: KarXT

Phase 3

Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Columbus, Ohio, United States and 290 other locations

The purpose of this study is to assess the efficacy and safety of trontinemab in participants with early symptomatic Alzheimer's disease...

Enrolling
Alzheimers Disease
Drug: Trontinemab
Other: Placebo

Phase 3

Roche
Roche

Columbus, Ohio, United States and 140 other locations

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