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Find clinical trials for Alzheimer's Disease in Durham, NC

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Related conditions:

Alzheimer Disease
Dementia
Cognitive Dysfunction
Mental Disorders
Brain Diseases
Psychomotor Agitation
Nervous System Diseases

Alzheimer's Disease trials near Durham, NC, USA:

Gene Therapy for APOE4 Homozygote of Alzheimer's Disease

clinical diagnosis varying from mild cognitive impairment due to Alzheimer's, mild dementia due to Alzheimer's disease, an ...

Active, not recruiting
Alzheimer Disease
Early Onset Alzheimer Disease
Biological: LX1001

Phase 1, Phase 2

Lexeo Therapeutics

Durham, North Carolina, United States and 3 other locations

This study is designed to evaluate safety and efficacy of fosgonimeton (ATH-1017) in the treatment of mild to moderate Alzheimer's disease...

Active, not recruiting
Alzheimer Disease
Dementia of Alzheimer Type
Drug: Placebo
Drug: ATH-1017

Phase 2, Phase 3

Athira Pharma
Athira Pharma

Durham, North Carolina, United States and 89 other locations

is superior to placebo on change from baseline of the Preclinical Alzheimer Cognitive Composite 5 (PACC5) at 216 weeks of treatment (A45 Tri...

Enrolling
Preclinical Alzheimer's Disease
Early Preclinical Alzheimer's Disease
Drug: Lecanemab
Drug: Placebo

Phase 3

Eisai
Eisai

Durham, North Carolina, United States and 117 other locations

Alzheimer's disease (AD) is a progressive, irreversible neurological disorder and is the most common cause of dementia in the elder...

Active, not recruiting
Alzheimer's Disease (AD)
Drug: Placebo for ABBV-552
Drug: ABBV-552

Phase 2

AbbVie
AbbVie

Raleigh, North Carolina, United States and 63 other locations

This study will be conducted to evaluate the efficacy of lecanemab in participants with early Alzheimer's disease (EAD) by determin...

Active, not recruiting
Early Alzheimer's Disease
Drug: Placebo
Drug: Lecanemab

Phase 3

Eisai
Eisai

Raleigh, North Carolina, United States and 246 other locations

The objective of this study is to determine the safety and tolerability of fosgonimeton (ATH-1017) in subjects with mild to moderate Alzheimer's...

Active, not recruiting
Alzheimer Disease
Drug: ATH-1017

Phase 2, Phase 3

Athira Pharma
Athira Pharma

Durham, North Carolina, United States and 75 other locations

who were administered gene therapy (LX1001) for the treatment of Alzheimer's disease in Study LX100101. A secondary objective is to...

Enrolling
Alzheimer Disease
Biological: LX1001

Phase 1

Lexeo Therapeutics

Durham, North Carolina, United States and 1 other location

to alleviate symptoms when given to people with mild to moderate Alzheimer Disease (AD) dementia. This is done by looking at partic...

Enrolling
Alzheimer Disease
Drug: Placebo
Drug: Mevidalen

Phase 2

Lilly
Lilly

Raleigh, North Carolina, United States and 44 other locations

The main purpose of this study is to evaluate the safety of LY3954068 in participants with early symptomatic Alzheimer's Disease (A...

Enrolling
Alzheimer Disease
Drug: Flortaucipir F18
Drug: LY3954068

Phase 1

Lilly
Lilly

Durham, North Carolina, United States and 11 other locations

This AR1001-ADP3-US01 protocol is a double-blind, randomized, placebo-controlled, multi- center, parallel-group comparison pivotal Phase 3 study to e...

Enrolling
Alzheimer Disease
Drug: Placebo
Drug: AR1001

Phase 3

AriBio

Greensboro, North Carolina, United States of America and 99 other locations

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