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Find clinical trials for Alzheimer's Disease in Durham, NC

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Related conditions:

Alzheimer Disease
Dementia
Cognitive Dysfunction
Mental Disorders
Psychomotor Agitation
Brain Diseases
Neurodegenerative Diseases

Alzheimer's Disease trials near Durham, NC, USA:

AHEAD 3-45 Study: A Study to Evaluate Efficacy and Safety of Treatment With Lecanemab in Participants With Preclinical Alzheimer's Disease and Elevated Amyloid and Also in Participants With Early Preclinical Alzheimer's Disease and Intermediate Amyloid

is superior to placebo on change from baseline of the Preclinical Alzheimer Cognitive Composite 5 (PACC5) at 216 weeks of treatment (A45 Tri...

Enrolling
Preclinical Alzheimer's Disease
Early Preclinical Alzheimer's Disease
Drug: Lecanemab
Drug: Placebo

Phase 3

Eisai
Eisai

Durham, North Carolina, United States and 117 other locations

This study will be conducted to evaluate the efficacy of lecanemab in participants with early Alzheimer's disease (EAD) by determin...

Active, not recruiting
Early Alzheimer's Disease
Drug: Placebo
Drug: Lecanemab

Phase 3

Eisai
Eisai

Raleigh, North Carolina, United States and 246 other locations

The purpose of this study is to evaluate the safety and efficacy of KarXT in adult participants with mild to severe Alzheimer's Disease...

Enrolling
Alzheimer Disease
Drug: Placebo
Drug: KarXT

Phase 3

Karuna Therapeutics
Karuna Therapeutics

Greensboro, North Carolina, United States and 189 other locations

who were administered gene therapy (LX1001) for the treatment of Alzheimer's disease in Study LX100101. A secondary objective is to...

Enrolling
Alzheimer Disease
Biological: LX1001

Phase 1

Lexeo Therapeutics

Durham, North Carolina, United States and 1 other location

The main purpose of this study is to evaluate the safety of LY3954068 in participants with early symptomatic Alzheimer's Disease (A...

Enrolling
Alzheimer Disease
Drug: Flortaucipir F18
Drug: LY3954068

Phase 1

Lilly
Lilly

Durham, North Carolina, United States and 11 other locations

to alleviate symptoms when given to people with mild to moderate Alzheimer Disease (AD) dementia. This is done by looking at partic...

Enrolling
Alzheimer Disease
Drug: Placebo
Drug: Mevidalen

Phase 2

Lilly
Lilly

Raleigh, North Carolina, United States and 60 other locations

This AR1001-ADP3-US01 protocol is a double-blind, randomized, placebo-controlled, multi- center, parallel-group comparison pivotal Phase 3 study to e...

Enrolling
Alzheimer Disease
Drug: Placebo
Drug: AR1001

Phase 3

AriBio

Greensboro, North Carolina, United States of America and 100 other locations

This study is being conducted to evaluate the long-term safety and efficacy of ALZ-801 in Early Alzheimer's disease (AD) subjects w...

Invitation-only
Early Alzheimer's Disease
Drug: Experimental: ALZ-801

Phase 3

Alzheon

Greensboro, North Carolina, United States of America and 43 other locations

In this study, researchers will learn more about a study drug called BIIB080. The study will focus on participants with mild cognitive impairment or...

Active, not recruiting
Mild Cognitive Impairment Due to Alzheimer's Disease
Alzheimer's Disease Dementia
Drug: BIIB080-matching placebo
Drug: BIIB080

Phase 2

Biogen
Biogen

Durham, North Carolina, United States and 137 other locations

The main purpose of this study is to evaluate the safety and efficacy of donanemab in participants with preclinical Alzheimer's Disease...

Active, not recruiting
Alzheimer Disease
Drug: Donanemab
Drug: Placebo

Phase 3

Lilly
Lilly

Raleigh, North Carolina, United States and 230 other locations

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