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Find clinical trials for Alzheimer's Disease in Durham, NC

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Related conditions:

Alzheimer Disease
Dementia
Cognitive Dysfunction
Mental Disorders
Brain Diseases
Nervous System Diseases
Neurocognitive Disorders

Alzheimer's Disease trials near Durham, NC, USA:

Gene Therapy for APOE4 Homozygote of Alzheimer's Disease

clinical diagnosis varying from mild cognitive impairment due to Alzheimer's, mild dementia due to Alzheimer's disease, an ...

Active, not recruiting
Alzheimer Disease
Early Onset Alzheimer Disease
Biological: LX1001

Phase 1, Phase 2

Lexeo Therapeutics

Durham, North Carolina, United States and 3 other locations

This study is designed to evaluate safety and efficacy of fosgonimeton (ATH-1017) in the treatment of mild to moderate Alzheimer's disease...

Active, not recruiting
Alzheimer Disease
Dementia of Alzheimer Type
Drug: Placebo
Drug: ATH-1017

Phase 2, Phase 3

Athira Pharma
Athira Pharma

Durham, North Carolina, United States and 89 other locations

is superior to placebo on change from baseline of the Preclinical Alzheimer Cognitive Composite 5 (PACC5) at 216 weeks of treatment (A45 Tri...

Enrolling
Preclinical Alzheimer's Disease
Early Preclinical Alzheimer's Disease
Drug: Lecanemab
Drug: Placebo

Phase 3

Eisai
Eisai

Durham, North Carolina, United States and 111 other locations

Alzheimer's disease (AD) is a progressive, irreversible neurological disorder and is the most common cause of dementia in the elder...

Active, not recruiting
Alzheimer's Disease (AD)
Drug: Placebo for ABBV-552
Drug: ABBV-552

Phase 2

AbbVie
AbbVie

Raleigh, North Carolina, United States and 63 other locations

This study will be conducted to evaluate the efficacy of lecanemab in participants with early Alzheimer's disease (EAD) by determin...

Active, not recruiting
Early Alzheimer's Disease
Drug: Lecanemab
Drug: Placebo

Phase 3

Eisai
Eisai

Raleigh, North Carolina, United States and 246 other locations

The objective of this study is to determine the safety and tolerability of fosgonimeton (ATH-1017) in subjects with mild to moderate Alzheimer's...

Invitation-only
Alzheimer Disease
Drug: ATH-1017

Phase 2, Phase 3

Athira Pharma
Athira Pharma

Durham, North Carolina, United States and 50 other locations

who were administered gene therapy (LX1001) for the treatment of Alzheimer's disease in Study LX100101. A secondary objective is to...

Enrolling
Alzheimer Disease
Biological: LX1001

Phase 1

Lexeo Therapeutics

Durham, North Carolina, United States and 1 other location

The main purpose of this study is to evaluate the safety of LY3954068 in participants with early symptomatic Alzheimer's Disease (A...

Not yet enrolling
Alzheimer Disease
Drug: LY3954068
Drug: Flortaucipir F18

Phase 1

Lilly
Lilly

Durham, North Carolina, United States and 10 other locations

This AR1001-ADP3-US01 protocol is a double-blind, randomized, placebo-controlled, multi- center, parallel-group comparison pivotal Phase 3 study to e...

Enrolling
Alzheimer Disease
Drug: Placebo
Drug: AR1001

Phase 3

AriBio

Greensboro, North Carolina, United States of America and 83 other locations

The primary purpose of this study is to evaluate the effect of SAGE-718 on cognitive performance in participants with Alzheimer's Disease...

Active, not recruiting
Alzheimer's Disease
Mild Dementia
Drug: SAGE-718-matching Placebo
Drug: SAGE-718

Phase 2

Sage Therapeutics
Sage Therapeutics

Raleigh, North Carolina, United States and 35 other locations

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