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Find clinical trials for Alzheimer's Disease in Pittsburgh, PA

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Related conditions:

Alzheimer Disease
Dementia
Cognitive Dysfunction
Mental Disorders
Brain Diseases
Nervous System Diseases
Neurocognitive Disorders

Alzheimer's Disease trials near Pittsburgh, PA, USA:

DIAN-TU Amyloid Removal Trial (ART) in Dominantly Inherited Alzheimer's Disease

This is an open label study to treat dominantly inherited Alzheimer's disease (DIAD) mutation carrier participants from the DIAN-TU...

Not yet enrolling
Alzheimer's Disease
Alzheimer's Disease, Familial
Drug: lecanemab

Phase 3

The Washington University
The Washington University

Pittsburgh, Pennsylvania, United States and 7 other locations

efficacy of investigational products in participants with an Alzheimer's disease-causing mutation by determining if treatment with ...

Enrolling
Alzheimers Disease
Alzheimers Disease, Familial
Drug: Solanezumab
Drug: Lecanemab

Phase 2, Phase 3

The Washington University
The Washington University

Pittsburgh, Pennsylvania, United States and 38 other locations

To assess the safety, tolerability, biomarker, cognitive, and clinical efficacy of investigational products in participants with an Alzheimer's...

Enrolling
Alzheimers Disease
Alzheimers Disease, Familial
Drug: Lecanemab
Drug: E2814

Phase 2, Phase 3

The Washington University
The Washington University

Pittsburgh, Pennsylvania, United States and 37 other locations

progression of AD, as compared to no stimulation (OFF), by measuring baseline (pre-implantation) to 12-month change in the integrated Alzheimer's...

Active, not recruiting
Alzheimer Disease
Device: DBS-f On
Device: DBS Off
Functional Neuromodulation

Pittsburgh, Pennsylvania, United States and 20 other locations

is superior to placebo on change from baseline of the Preclinical Alzheimer Cognitive Composite 5 (PACC5) at 216 weeks of treatment (A45 Tri...

Enrolling
Preclinical Alzheimer's Disease
Early Preclinical Alzheimer's Disease
Drug: Lecanemab
Drug: Placebo

Phase 3

Eisai
Eisai

Pittsburgh, Pennsylvania, United States and 111 other locations

The primary objective is to evaluate the safety and tolerability of aducanumab over 100 weeks of treatment after a wash-out period imposed by discont...

Active, not recruiting
Alzheimer's Disease
Drug: Aducanumab

Phase 3

Biogen
Biogen

Pittsburgh, Pennsylvania, United States and 296 other locations

This is an extension study of the Phase 3 Studies 15-AVP-786-301, 15-AVP-786-302, and 17-AVP-786-305, which also allows participants from the Phase 2...

Enrolling
Agitation in Patients With Dementia of the Alzheimer's Type
Drug: AVP-786

Phase 3

Otsuka
Otsuka

Beaver, Pennsylvania, United States and 275 other locations

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