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Find clinical trials for Alzheimer's Disease in Pittsburgh, PA

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Related conditions:

Alzheimer Disease
Dementia
Cognitive Dysfunction
Mental Disorders
Brain Diseases
Psychomotor Agitation
Nervous System Diseases

Alzheimer's Disease trials near Pittsburgh, PA, USA:

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001

efficacy of investigational products in participants with an Alzheimer's disease-causing mutation by determining if treatment with ...

Enrolling
Alzheimers Disease
Alzheimers Disease, Familial
Drug: Solanezumab
Drug: E2814

Phase 2, Phase 3

The Washington University
The Washington University

Pittsburgh, Pennsylvania, United States and 37 other locations

To assess the safety, tolerability, biomarker, cognitive, and clinical efficacy of investigational products in participants with an Alzheimer's...

Active, not recruiting
Alzheimers Disease
Alzheimers Disease, Familial
Drug: Lecanemab
Drug: Matching Placebo (E2814)

Phase 2, Phase 3

The Washington University
The Washington University

Pittsburgh, Pennsylvania, United States and 37 other locations

progression of AD, as compared to no stimulation (OFF), by measuring baseline (pre-implantation) to 12-month change in the integrated Alzheimer's...

Active, not recruiting
Alzheimer Disease
Device: DBS-f On
Device: DBS Off
Functional Neuromodulation

Pittsburgh, Pennsylvania, United States and 20 other locations

is superior to placebo on change from baseline of the Preclinical Alzheimer Cognitive Composite 5 (PACC5) at 216 weeks of treatment (A45 Tri...

Enrolling
Preclinical Alzheimer's Disease
Early Preclinical Alzheimer's Disease
Drug: Lecanemab
Drug: Placebo

Phase 3

Eisai
Eisai

Pittsburgh, Pennsylvania, United States and 117 other locations

investigational study drugs in participants who are known to have an Alzheimer's disease (AD)-causing mutation. Part 1 will determi...

Begins enrollment this month
Alzheimers Disease
Alzheimers Disease, Familial
Drug: Matching Placebo (Gantenerumab)
Drug: Gantenerumab

Phase 2, Phase 3

The Washington University
The Washington University

Pittsburgh, Pennsylvania, United States and 34 other locations

This is an extension study of the Phase 3 Studies 15-AVP-786-301, 15-AVP-786-302, and 17-AVP-786-305, which also allows participants from the Phase 2...

Enrolling
Agitation in Patients With Dementia of the Alzheimer's Type
Drug: AVP-786

Phase 3

Otsuka
Otsuka

Beaver, Pennsylvania, United States and 275 other locations

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