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The purpose of this study is to evaluate the efficacy and safety of verekitug (UPB-101) in participants with severe asthma. The study will e...
Phase 2
Birmingham, Alabama, United States of America and 122 other locations
The study is being conducted to evaluate the effect of 3 dosing regimens of povorcitinib on pulmonary function
Phase 2
Birmingham, Alabama, United States of America and 84 other locations
BID using a dry-powder inhaler at one dose level over a 12-week Treatment period in adult participants with uncontrolled moderate-to-severe asthma...
Phase 2
Birmingham, Alabama, United States and 158 other locations
and safety of Atuliflapon administered once daily over a 12-week treatment period to adult participants with moderate to severe uncontrolled asthma...
Phase 2
Birmingham, Alabama, United States and 381 other locations
of clinically significant exacerbations in participants with severe asthma with an eosinophilic phenotype. Throughout the study, all partici...
Phase 3
Birmingham, Alabama, United States and 419 other locations
The primary purpose of this study is to evaluate the effects of Fluticasone Furoate (FF)/ Umeclidinium (UMEC)/ Vilanterol (VI) on lung function compa...
Phase 3
Birmingham, Alabama, United States and 79 other locations
decline in adult patients with uncontrolled moderate to severe asthma.The estimated duration is 4±1 weeks of screening and run-in period, fo...
Phase 4
Cullman, Alabama, United States of America and 240 other locations
The purpose of the study is to evaluate effect of benralizumab on structural and lung function changes in severe eosinophilic asthmatics.Changes will...
Phase 4
Birmingham, Alabama, United States and 52 other locations
The primary objective is to assess the safety and tolerability of TAB004 as monotherapy and in combination with toripalimab in subjects with selected...
Phase 1
Birmingham, Alabama, United States and 23 other locations
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