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Find clinical trials for Asthma in Birmingham, AL

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Related conditions:

Pulmonary Eosinophilia
Allergic Rhinitis
Rhinitis
Chronic Obstructive Pulmonary Disease
Nasal Polyps
Respiratory Tract Diseases
Rhinosinusitis

Asthma trials near Birmingham, AL, USA:

A Study to Investigate the Efficacy and Safety of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALIANT)

The purpose of this study is to evaluate the efficacy and safety of verekitug (UPB-101) in participants with severe asthma. The study will e...

Active, not recruiting
Severe Asthma
Drug: Placebo
Drug: Verekitug (UPB-101)

Phase 2

Upstream Bio

Birmingham, Alabama, United States of America and 156 other locations

BID using a dry-powder inhaler at one dose level over a 12-week Treatment period in adult participants with uncontrolled moderate-to-severe asthma...

Active, not recruiting
Asthma
Drug: AZD4604
Other: Placebo

Phase 2

AstraZeneca
AstraZeneca

Birmingham, Alabama, United States and 123 other locations

The study is being conducted to evaluate the effect of 3 dosing regimens of povorcitinib on pulmonary function

Enrolling
Moderate to Severe Asthma
Drug: ICS-LABA
Other: placebo

Phase 2

Incyte
Incyte

Birmingham, Alabama, United States of America and 84 other locations

and safety of Atuliflapon administered once daily over a 12-week treatment period to adult participants with moderate to severe uncontrolled asthma...

Active, not recruiting
Asthma
Drug: Placebo
Drug: Atuliflapon

Phase 2

AstraZeneca
AstraZeneca

Birmingham, Alabama, United States and 266 other locations

The primary purpose of this study is to evaluate the effects of Fluticasone Furoate (FF)/ Umeclidinium (UMEC)/ Vilanterol (VI) on lung function compa...

Enrolling
Asthma
Drug: FF/VI
Device: ELLIPTA

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Birmingham, Alabama, United States and 41 other locations

inhaler (eMDPI) compared to ABS eMDPI in decreasing severe clinical asthma exacerbation (CAEs).Secondary Objectives:To evaluate the efficacy...

Enrolling
Asthma
Drug: Albuterol sulfate
Drug: TEV-56248

Phase 3

Teva Pharmaceuticals
Teva Pharmaceuticals

Birmingham, Alabama, United States and 389 other locations

decline in adult patients with uncontrolled moderate to severe asthma.The estimated duration is 4±1 weeks of screening and run-in period, fo...

Enrolling
Asthma
Drug: Placebo
Drug: Dupilumab

Phase 4

Sanofi
Sanofi

Cullman, Alabama, United States of America and 255 other locations

The purpose of the study is to evaluate effect of benralizumab on structural and lung function changes in severe eosinophilic asthmatics.Changes will...

Active, not recruiting
Asthma
Biological: Benralizumab
Biological: Placebo

Phase 4

AstraZeneca
AstraZeneca

Birmingham, Alabama, United States and 34 other locations

New

clinical endpoint bioequivalence study in adult participants with asthma.The study design includes up to a 2-week Screening period, at least...

Not yet enrolling
Respiratory
Combination Product: Placebo
Combination Product: Breo Ellipta

Phase 3

Sandoz
Sandoz

Cullman, Alabama, United States and 5 other locations

This research is being done to test if a drug called omalizumab can help people with Chronic Obstructive Pulmonary Disease (COPD) and allergies.Each...

Not yet enrolling
Chronic Obstructive Pulmonary Disease (COPD)
Allergies
Drug: Omalizumab (Xolair®)
Drug: Sodium Chloride (NaCl) 0.9 %

Phase 2

Johns Hopkins University
Johns Hopkins University

Birmingham, Alabama, United States and 22 other locations

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