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This is a multi-center, double-blind, placebo-controlled, randomized trial of dupilumab adjunctive therapy for prevention of asthma exacerba....
Phase 2
Boston, Massachusetts, United States and 6 other locations
28-week Phase 3 Efficacy and Safety Study of Tezepelumab in Reducing Oral Corticosteroid Use in Adults with Oral Corticosteroid Dependent Asthma...
Phase 3
Boston, Massachusetts, United States and 121 other locations
To assess the efficacy and safety of tezepelumab in pediatric participants with severe uncontrolled asthma on medium to high-dose inhaled co...
Phase 3
Boston, Massachusetts, United States and 97 other locations
to therapy acting directly on the anti-IL-4R. This will be conducted by examining the effect of a 48 week therapy with dupilumab on the rate of asthma...
Phase 4
Boston, Massachusetts, United States and 6 other locations
To asses effectiveness and safety of tezepelumab in adult and adolescent participants with severe asthma including several under-studied pop...
Phase 4
Warwick, Rhode Island, United States and 44 other locations
This study will assess the efficacy and safety of GSK3511294 (Depemokimab) as an adjunctive therapy in participants with severe uncontrolled asthma...
Phase 3
Burlington, Massachusetts, United States and 141 other locations
This is a US study comparing the efficacy and safety of BDA MDI [Budesonide/Albuterol Sulfate (BDA) metered dose inhaler (MDI)] with AS [Albuterol Su...
Phase 3
Woonsocket, Rhode Island, United States and 60 other locations
ARS-1 is being developed for patients as a needleless alternative route of epinephrine administration for the management of refractory asthma...
Phase 2
Boston, Massachusetts, United States and 3 other locations
inhaler (eMDPI) compared to ABS eMDPI in decreasing severe clinical asthma exacerbation (CAEs).Secondary Objectives:To evaluate the efficacy...
Phase 3
North Dartmouth, Massachusetts, United States and 100 other locations
and safety of Atuliflapon administered once daily over a 12-week treatment period to adult participants with moderate to severe uncontrolled asthma...
Phase 2
Boston, Massachusetts, United States and 350 other locations
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