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Find clinical trials for Asthma in Cleveland, OH

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Related conditions:

Pulmonary Eosinophilia
Allergic Rhinitis
Rhinitis
Respiratory Tract Diseases
Chronic Obstructive Pulmonary Disease
Conjunctivitis
Dust Mite Allergy

Asthma trials near Cleveland, OH, USA:

A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA)

in patients ≥ 6 to \< 18 years of age with severe eosinophilic asthma, including a well-documented history of asthma exacerbations ...

Enrolling
Asthma
Drug: Placebo
Drug: Benralizumab

Phase 3

AstraZeneca
AstraZeneca

Cleveland, Ohio, United States and 87 other locations

The purpose of this study is to evaluate the efficacy and safety of verekitug (UPB-101) in participants with severe asthma. The study will e...

Active, not recruiting
Severe Asthma
Drug: Placebo
Drug: Verekitug (UPB-101)

Phase 2

Upstream Bio

Munroe Falls, Ohio, United States and 155 other locations

The purpose of this study is to evaluate dexpramipexole as an add-on oral therapy in participants with inadequately controlled eosinophilic asthma...

Active, not recruiting
Asthma Attack
Asthma; Eosinophilic
Drug: Dexpramipexole Dihydrochloride
Drug: Placebo

Phase 3

Areteia Therapeutics

Cleveland, Ohio, United States and 335 other locations

to therapy acting directly on the anti-IL-4R. This will be conducted by examining the effect of a 48 week therapy with dupilumab on the rate of asthma...

Enrolling
Asthma
Other: Placebo
Drug: Dupilumab

Phase 4

Boston Children's Hospital
Boston Children's Hospital

Cleveland, Ohio, United States and 5 other locations

To assess the efficacy and safety of tezepelumab in pediatric participants with severe uncontrolled asthma on medium to high-dose inhaled co...

Enrolling
Asthma
Biological: Tezepelumab
Other: Placebo

Phase 3

AstraZeneca
AstraZeneca

Cleveland, Ohio, United States and 140 other locations

treatment in children 2 to \<6 years of age with uncontrolled asthma and/or recurrent severe asthmatic wheeze. The study will be conducted i...

Enrolling
Asthma
Wheezing
Drug: Placebo
Drug: Dupilumab

Phase 3

Sanofi
Sanofi

Cleveland, Ohio, United States and 74 other locations

The primary purpose of this study is to evaluate the effects of Fluticasone Furoate (FF)/ Umeclidinium (UMEC)/ Vilanterol (VI) on lung function compa...

Enrolling
Asthma
Drug: FF/VI
Device: ELLIPTA

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Cleveland, Ohio, United States and 41 other locations

This is a parallel-group, Phase 2, randomized, double-blind, placebo-controlled, 2-arm study for the treatment of asthma.The purpose of this...

Enrolling
Asthma
Drug: Short-Acting Beta Agonists (SABA)
Drug: Fluticasone/salmeterol

Phase 2

Sanofi
Sanofi

Cleveland, Ohio, United States and 238 other locations

A 3-year cluster randomized controlled trial of the impact of a quality improvement and clinical decision support package versus usual care for patie...

Enrolling
Chronic Obstructive Pulmonary Disease
Other: CONQUEST Quality Improvement Program
Observational and Pragmatic Research Institute

Cleveland, Ohio, United States and 2 other locations

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