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in patients ≥ 6 to \< 18 years of age with severe eosinophilic asthma, including a well-documented history of asthma exacerbations ...
Phase 3
Cleveland, Ohio, United States and 83 other locations
The purpose of this study is to evaluate the efficacy and safety of verekitug (UPB-101) in participants with severe asthma. The study will e...
Phase 2
Munroe Falls, Ohio, United States and 122 other locations
To assess the efficacy and safety of tezepelumab in pediatric participants with severe uncontrolled asthma on medium to high-dose inhaled co...
Phase 3
Cleveland, Ohio, United States and 115 other locations
to therapy acting directly on the anti-IL-4R. This will be conducted by examining the effect of a 48 week therapy with dupilumab on the rate of asthma...
Phase 4
Cleveland, Ohio, United States and 6 other locations
treatment in children 2 to \<6 years of age with uncontrolled asthma and/or recurrent severe asthmatic wheeze. The study will be conducted i...
Phase 3
Cleveland, Ohio, United States and 57 other locations
of clinically significant exacerbations in participants with severe asthma with an eosinophilic phenotype. Throughout the study, all partici...
Phase 3
Cleveland, Ohio, United States and 419 other locations
The primary purpose of this study is to evaluate the effects of Fluticasone Furoate (FF)/ Umeclidinium (UMEC)/ Vilanterol (VI) on lung function compa...
Phase 3
Cleveland, Ohio, United States and 79 other locations
Primary Objective-To evaluate the efficacy of dupilumab compared to omalizumab in reducing the polyp size and improving sense of smellSecondary Objec...
Phase 4
Cleveland, Ohio, United States and 94 other locations
A 3-year cluster randomized controlled trial of the impact of a quality improvement and clinical decision support package versus usual care for patie...
Cleveland, Ohio, United States and 2 other locations
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