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Find clinical trials for Asthma in Cleveland, OH

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Related conditions:

Pulmonary Eosinophilia
Nasal Polyps
Rhinosinusitis
Allergic Rhinitis
Rhinitis
Sinusitis
Respiration Disorders

Asthma trials near Cleveland, OH, USA:

A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA)

in patients ≥ 6 to \< 18 years of age with severe eosinophilic asthma, including a well-documented history of asthma exacerbations ...

Enrolling
Asthma
Drug: Placebo
Drug: Benralizumab

Phase 3

AstraZeneca
AstraZeneca

Cleveland, Ohio, United States and 83 other locations

The purpose of this study is to evaluate the efficacy and safety of verekitug (UPB-101) in participants with severe asthma. The study will e...

Enrolling
Severe Asthma
Drug: Placebo
Drug: Verekitug (UPB-101)

Phase 2

Upstream Bio

Munroe Falls, Ohio, United States and 122 other locations

to therapy acting directly on the anti-IL-4R. This will be conducted by examining the effect of a 48 week therapy with dupilumab on the rate of asthma...

Enrolling
Asthma
Other: Placebo
Drug: Dupilumab

Phase 4

Boston Children's Hospital
Boston Children's Hospital

Cleveland, Ohio, United States and 6 other locations

To assess the efficacy and safety of tezepelumab in pediatric participants with severe uncontrolled asthma on medium to high-dose inhaled co...

Enrolling
Asthma
Biological: Tezepelumab
Other: Placebo

Phase 3

AstraZeneca
AstraZeneca

Cleveland, Ohio, United States and 115 other locations

treatment in children 2 to \<6 years of age with uncontrolled asthma and/or recurrent severe asthmatic wheeze. The study will be conducted i...

Enrolling
Asthma
Wheezing
Drug: Placebo
Drug: Dupilumab

Phase 3

Sanofi
Sanofi

Cleveland, Ohio, United States and 57 other locations

of clinically significant exacerbations in participants with severe asthma with an eosinophilic phenotype. Throughout the study, all partici...

Active, not recruiting
Asthma
Biological: GSK3511294 (Depemokimab)
Biological: Mepolizumab

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Cleveland, Ohio, United States and 419 other locations

The primary purpose of this study is to evaluate the effects of Fluticasone Furoate (FF)/ Umeclidinium (UMEC)/ Vilanterol (VI) on lung function compa...

Enrolling
Asthma
Drug: FF/VI
Device: ELLIPTA

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Cleveland, Ohio, United States and 79 other locations

Primary Objective-To evaluate the efficacy of dupilumab compared to omalizumab in reducing the polyp size and improving sense of smellSecondary Objec...

Active, not recruiting
Asthma
Chronic Rhinosinusitis With Nasal Polyps
Drug: Omalizumab
Drug: Placebo

Phase 4

Sanofi
Sanofi

Cleveland, Ohio, United States and 94 other locations

A 3-year cluster randomized controlled trial of the impact of a quality improvement and clinical decision support package versus usual care for patie...

Enrolling
Chronic Obstructive Pulmonary Disease
Other: CONQUEST Quality Improvement Program
Observational and Pragmatic Research Institute

Cleveland, Ohio, United States and 2 other locations

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