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Find clinical trials for Asthma in Durham, NC

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Related conditions:

Pulmonary Eosinophilia
Allergic Rhinitis
Rhinitis
Chronic Obstructive Pulmonary Disease
Dust Mite Allergy
Lung Diseases
Disease

Asthma trials near Durham, NC, USA:

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Eosinophilic Asthma (EXHALE-4)

The purpose of this study is to evaluate dexpramipexole as an add-on oral therapy in participants with inadequately controlled eosinophilic asthma...

Active, not recruiting
Asthma Attack
Asthma; Eosinophilic
Drug: Dexpramipexole Dihydrochloride
Drug: Placebo

Phase 3

Areteia Therapeutics

Raleigh, North Carolina, United States and 335 other locations

To assess the efficacy and safety of tezepelumab in pediatric participants with severe uncontrolled asthma on medium to high-dose inhaled co...

Enrolling
Asthma
Biological: Tezepelumab
Other: Placebo

Phase 3

AstraZeneca
AstraZeneca

Chapel Hill, North Carolina, United States and 142 other locations

Phase 2 study to evaluate the safety, tolerability, PK, immunogenicity, and pharmacodynamics of solriktug with adult participants with asthma...

Active, not recruiting
Asthma
Biological: NSI-8226
Biological: Placebo

Phase 2

Uniquity One (UNI)

Raleigh, North Carolina, United States of America and 70 other locations

The purpose of this study is to assess the PD equivalence of the approved asthma combination therapy, BDA, delivered using the proposed repl....

Active, not recruiting
Asthma
Drug: BDA MDI HFO 160/180 μg
Drug: BDA MDI HFA 160/180 μg

Phase 3

AstraZeneca
AstraZeneca

Raleigh, North Carolina, United States and 127 other locations

treatment in children 2 to \<6 years of age with uncontrolled asthma and/or recurrent severe asthmatic wheeze. The study will be conducted i...

Enrolling
Asthma
Wheezing
Drug: Placebo
Drug: Dupilumab

Phase 3

Sanofi
Sanofi

Chapel Hill, North Carolina, United States and 74 other locations

of AMG 691 as single doses (healthy participants only) and multiple doses in healthy participants and participants with mild-to-moderate asthma...

Active, not recruiting
Asthma
Drug: Placebo
Drug: AMG 691

Phase 1

Amgen
Amgen

Chapel Hill, North Carolina, United States and 21 other locations

This Phase 2b study is designed to evaluate the safety and efficacy of KT-621 in participants with uncontrolled moderate to severe eosinophilic asthma...

Enrolling
Eosinophilic Asthma
Drug: KT-621
Other: Placebo

Phase 2

Kymera Therapeutics

Chapel Hill, North Carolina, United States and 57 other locations

inhaler (eMDPI) compared to ABS eMDPI in decreasing severe clinical asthma exacerbation (CAEs).Secondary Objectives:To evaluate the efficacy...

Active, not recruiting
Asthma
Drug: TEV-56248
Drug: Albuterol sulfate

Phase 3

Teva Branded Pharmaceutical Products R&D LLC

Chapel Hill, North Carolina, United States and 394 other locations

The primary objective of the trial is to evaluate the efficacy of fluticasone propionate/albuterol sulfate multidose dry powder inhaler with electron...

Enrolling
Asthma
Drug: Placebo
Drug: FP

Phase 3

Teva Branded Pharmaceutical Products R&D LLC

Raleigh, North Carolina, United States and 183 other locations

This study will assess the efficacy and safety of daily OM-85 treatment compared to placebo in children aged 6 months to 5 years with recurrent wheez...

Active, not recruiting
Wheezing Lower Respiratory Illness
Recurrent Wheezing
Drug: OM-85
Drug: Placebo

Phase 2

OM Pharma

Chapel Hill, North Carolina, United States and 37 other locations

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