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Find clinical trials for Asthma in Durham, NC

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Related conditions:

Pulmonary Eosinophilia
Allergic Rhinitis
Rhinitis
Chronic Obstructive Pulmonary Disease
Nasal Polyps
Respiratory Tract Diseases
Rhinosinusitis

Asthma trials near Durham, NC, USA:

Study to Investigate Changes in Airway Inflammation, Symptoms, and Rescue Therapy Utilization With AIRSUPRA Compared to Albuterol as Needed in Adults With Mild Asthma (DARWIN)

The purpose of this study is to compare the efficacy and safety of albuterol/budesonide to albuterol in changes in airway inflammation, asthma...

Enrolling
Mild Asthma
Combination Product: Albuterol
Combination Product: Albuterol/Budesonide

Phase 4

AstraZeneca
AstraZeneca

Raleigh, North Carolina, United States and 18 other locations

This study will assess the efficacy and safety of dexpramipexole as an adjunctive oral therapy in participants with inadequately controlled asthma...

Enrolling
Asthma
Asthma; Eosinophilic
Drug: Placebo
Drug: Dexpramipexole Dihydrochloride

Phase 3

Areteia Therapeutics

Raleigh, North Carolina, United States and 401 other locations

The purpose of this study is to evaluate dexpramipexole as an add-on oral therapy in participants with inadequately controlled eosinophilic asthma...

Active, not recruiting
Asthma Attack
Asthma; Eosinophilic
Drug: Dexpramipexole Dihydrochloride
Drug: Placebo

Phase 3

Areteia Therapeutics

Raleigh, North Carolina, United States and 335 other locations

To assess the efficacy and safety of tezepelumab in pediatric participants with severe uncontrolled asthma on medium to high-dose inhaled co...

Enrolling
Asthma
Biological: Tezepelumab
Other: Placebo

Phase 3

AstraZeneca
AstraZeneca

Chapel Hill, North Carolina, United States and 140 other locations

The primary objective of this study is to describe the efficacy of rocatinlimab in reducing asthma exacerbations....

Enrolling
Asthma
Drug: Placebo
Drug: Rocatinlimab

Phase 2

Amgen
Amgen

Durham, North Carolina, United States and 154 other locations

The purpose of this study is to assess the PD equivalence of the approved asthma combination therapy, BDA, delivered using the proposed repl....

Enrolling
Asthma
Drug: BDA MDI HFO 160/180 μg
Drug: BDA MDI HFA 160/180 μg

Phase 3

AstraZeneca
AstraZeneca

Raleigh, North Carolina, United States and 142 other locations

treatment in children 2 to \<6 years of age with uncontrolled asthma and/or recurrent severe asthmatic wheeze. The study will be conducted i...

Enrolling
Asthma
Wheezing
Drug: Placebo
Drug: Dupilumab

Phase 3

Sanofi
Sanofi

Chapel Hill, North Carolina, United States and 72 other locations

of AMG 691 as single doses (healthy participants only) and multiple doses in healthy participants and participants with mild-to-moderate asthma...

Enrolling
Asthma
Drug: Placebo
Drug: AMG 691

Phase 1

Amgen
Amgen

Chapel Hill, North Carolina, United States and 13 other locations

administered via a dry powder inhaler in adults with uncontrolled asthma at risk of exacerbations, receiving medium -to -high dose inhaled c...

Enrolling
Asthma
Device: Inhaler
Drug: AZD8630

Phase 2

AstraZeneca
AstraZeneca

Raleigh, North Carolina, United States and 231 other locations

Locations recently updated

inhaler (eMDPI) compared to ABS eMDPI in decreasing severe clinical asthma exacerbation (CAEs).Secondary Objectives:To evaluate the efficacy...

Enrolling
Asthma
Drug: Albuterol sulfate
Drug: TEV-56248

Phase 3

Teva Pharmaceuticals
Teva Pharmaceuticals

Chapel Hill, North Carolina, United States and 389 other locations

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