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The purpose of this study is to compare the efficacy and safety of albuterol/budesonide to albuterol in changes in airway inflammation, asthma...
Phase 4
Raleigh, North Carolina, United States and 18 other locations
This study will assess the efficacy and safety of dexpramipexole as an adjunctive oral therapy in participants with inadequately controlled asthma...
Phase 3
Raleigh, North Carolina, United States and 401 other locations
The purpose of this study is to evaluate dexpramipexole as an add-on oral therapy in participants with inadequately controlled eosinophilic asthma...
Phase 3
Raleigh, North Carolina, United States and 335 other locations
To assess the efficacy and safety of tezepelumab in pediatric participants with severe uncontrolled asthma on medium to high-dose inhaled co...
Phase 3
Chapel Hill, North Carolina, United States and 140 other locations
The primary objective of this study is to describe the efficacy of rocatinlimab in reducing asthma exacerbations....
Phase 2
Durham, North Carolina, United States and 154 other locations
The purpose of this study is to assess the PD equivalence of the approved asthma combination therapy, BDA, delivered using the proposed repl....
Phase 3
Raleigh, North Carolina, United States and 142 other locations
treatment in children 2 to \<6 years of age with uncontrolled asthma and/or recurrent severe asthmatic wheeze. The study will be conducted i...
Phase 3
Chapel Hill, North Carolina, United States and 72 other locations
of AMG 691 as single doses (healthy participants only) and multiple doses in healthy participants and participants with mild-to-moderate asthma...
Phase 1
Chapel Hill, North Carolina, United States and 13 other locations
administered via a dry powder inhaler in adults with uncontrolled asthma at risk of exacerbations, receiving medium -to -high dose inhaled c...
Phase 2
Raleigh, North Carolina, United States and 231 other locations
inhaler (eMDPI) compared to ABS eMDPI in decreasing severe clinical asthma exacerbation (CAEs).Secondary Objectives:To evaluate the efficacy...
Phase 3
Chapel Hill, North Carolina, United States and 389 other locations
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