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Find clinical trials for Asthma in Durham, NC

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Related conditions:

Pulmonary Eosinophilia
Allergic Rhinitis
Rhinitis
Respiratory Tract Diseases
Chronic Obstructive Pulmonary Disease
Conjunctivitis
Dust Mite Allergy

Asthma trials near Durham, NC, USA:

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Eosinophilic Asthma (EXHALE-4)

The purpose of this study is to evaluate dexpramipexole as an add-on oral therapy in participants with inadequately controlled eosinophilic asthma...

Active, not recruiting
Asthma Attack
Asthma; Eosinophilic
Drug: Dexpramipexole Dihydrochloride
Drug: Placebo

Phase 3

Areteia Therapeutics

Raleigh, North Carolina, United States and 335 other locations

To assess the efficacy and safety of tezepelumab in pediatric participants with severe uncontrolled asthma on medium to high-dose inhaled co...

Enrolling
Asthma
Biological: Tezepelumab
Other: Placebo

Phase 3

AstraZeneca
AstraZeneca

Chapel Hill, North Carolina, United States and 140 other locations

The primary objective of this study is to describe the efficacy of rocatinlimab in reducing asthma exacerbations....

Active, not recruiting
Asthma
Drug: Placebo
Drug: Rocatinlimab

Phase 2

Amgen
Amgen

Durham, North Carolina, United States and 154 other locations

The purpose of this study is to assess the PD equivalence of the approved asthma combination therapy, BDA, delivered using the proposed repl....

Enrolling
Asthma
Drug: BDA MDI HFO 160/180 μg
Drug: BDA MDI HFA 160/180 μg

Phase 3

AstraZeneca
AstraZeneca

Raleigh, North Carolina, United States and 142 other locations

treatment in children 2 to \<6 years of age with uncontrolled asthma and/or recurrent severe asthmatic wheeze. The study will be conducted i...

Enrolling
Asthma
Wheezing
Drug: Placebo
Drug: Dupilumab

Phase 3

Sanofi
Sanofi

Chapel Hill, North Carolina, United States and 74 other locations

of AMG 691 as single doses (healthy participants only) and multiple doses in healthy participants and participants with mild-to-moderate asthma...

Enrolling
Asthma
Drug: Placebo
Drug: AMG 691

Phase 1

Amgen
Amgen

Chapel Hill, North Carolina, United States and 15 other locations

inhaler (eMDPI) compared to ABS eMDPI in decreasing severe clinical asthma exacerbation (CAEs).Secondary Objectives:To evaluate the efficacy...

Enrolling
Asthma
Drug: Albuterol sulfate
Drug: TEV-56248

Phase 3

Teva Pharmaceuticals
Teva Pharmaceuticals

Chapel Hill, North Carolina, United States and 393 other locations

The primary objective of the trial is to evaluate the efficacy of fluticasone propionate/albuterol sulfate multidose dry powder inhaler with electron...

Enrolling
Asthma
Drug: Placebo
Drug: FP

Phase 3

Teva Pharmaceuticals
Teva Pharmaceuticals

Raleigh, North Carolina, United States and 132 other locations

clinical endpoint bioequivalence study in adult participants with asthma.The study design includes up to a 2-week Screening period, at least...

Not yet enrolling
Respiratory
Combination Product: Placebo
Combination Product: Breo Ellipta

Phase 3

Sandoz
Sandoz

Raleigh, North Carolina, United States and 5 other locations

This study will assess the efficacy and safety of daily OM-85 treatment compared to placebo in children aged 6 months to 5 years with recurrent wheez...

Enrolling
Wheezing Lower Respiratory Illness
Recurrent Wheezing
Drug: OM-85
Drug: Placebo

Phase 2

OM Pharma

Chapel Hill, North Carolina, United States and 38 other locations

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