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Find clinical trials for Asthma in Durham, NC

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Related conditions:

Pulmonary Eosinophilia
Chronic Obstructive Pulmonary Disease
Obstructive Lung Diseases
Allergic Rhinitis
Nasal Polyps
Rhinitis
Lung Diseases

Asthma trials near Durham, NC, USA:

A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma (HORIZON)

To assess the efficacy and safety of tezepelumab in pediatric participants with severe uncontrolled asthma on medium to high-dose inhaled co...

Enrolling
Asthma
Biological: Tezepelumab
Other: Placebo

Phase 3

AstraZeneca
AstraZeneca

Chapel Hill, North Carolina, United States and 100 other locations

The overall aim in Part 1 is to compare the pharmacokinetic (PK)/pharmacodynamics (PD) relationship in intravenous (IV) versus subcutaneous (SQ) terb...

Enrolling
Asthma
Drug: Terbutaline

Phase 2, Phase 3

Kanecia Obie Zimmerman

Durham, North Carolina, United States

trifenatate (FF/UMEC/VI) with inhaled corticosteroids/long-acting beta-2 agonists (ICS/LABA) in adult participants with uncontrolled asthma...

Enrolling
Asthma
Drug: Inhaled corticosteroids/long-acting beta-2 agonists
Drug: Fluticasone furoate/umeclidinium bromide/vilanterol trifenatate

Phase 4

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Raleigh, North Carolina, United States and 67 other locations

To asses effectiveness and safety of tezepelumab in adult and adolescent participants with severe asthma including several under-studied pop...

Enrolling
Asthma
Drug: Tezepelumab

Phase 4

AstraZeneca
AstraZeneca

Durham, North Carolina, United States and 44 other locations

This is a US study comparing the efficacy and safety of BDA MDI \[Budesonide/Albuterol Sulfate (BDA) metered dose inhaler (MDI)\] with AS \[Albuterol...

Active, not recruiting
Asthma
Drug: BDA MDI
Drug: AS MDI

Phase 3

Avillion
Avillion

Raleigh, North Carolina, United States of America and 60 other locations

treatment in children 2 to \<6 years of age with uncontrolled asthma and/or recurrent severe asthmatic wheeze. The study will be conducted i...

Enrolling
Asthma
Wheezing
Drug: Placebo
Drug: Dupilumab

Phase 3

Sanofi
Sanofi

Chapel Hill, North Carolina, United States and 27 other locations

and formoterol fumarate metered dose inhaler relative to budesonide metered dose inhaler in adults and adolescents with inadequately controlled asthma...

Enrolling
Asthma
Drug: BFF MDI 160/9.6 μg BID (320/19.2μg/day)
Drug: BD MDI 160 μg BID (320 μg/day)

Phase 3

AstraZeneca
AstraZeneca

Raleigh, North Carolina, United States and 139 other locations

inhaler (eMDPI) compared to ABS eMDPI in decreasing severe clinical asthma exacerbation (CAEs).Secondary Objectives:To evaluate the efficacy...

Enrolling
Asthma
Drug: Albuterol sulfate
Drug: TEV-56248

Phase 3

Teva Pharmaceuticals
Teva Pharmaceuticals

Chapel Hill, North Carolina, United States and 122 other locations

The purpose of this study is to compare the superiority of CHF 1535 compared to CHF 718 in subjects with asthma on medium or high dose inhal...

Active, not recruiting
Asthma
Drug: Beclomethasone Dipropionate/Formoterol Fumarate
Drug: Beclomethasone Dipropionate

Phase 3

Chiesi
Chiesi

Raleigh, North Carolina, United States and 90 other locations

variable length study to evaluate the efficacy and safety of budesonide/glycopyrronium/formoterol inhaler in adults and adolescents with severe asthma...

Enrolling
Asthma
Drug: BFF pMDI 320/9 μg
Drug: BGF MDI 320/14.4/9.6 μg

Phase 3

AstraZeneca
AstraZeneca

Greensboro, North Carolina, United States and 448 other locations

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