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Find clinical trials for Asthma in Durham, NC

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Related conditions:

Pulmonary Eosinophilia
Nasal Polyps
Rhinosinusitis
Allergic Rhinitis
Rhinitis
Chronic Obstructive Pulmonary Disease
Lung Diseases

Asthma trials near Durham, NC, USA:

Study to Investigate Changes in Airway Inflammation, Symptoms, and Rescue Therapy Utilization With AIRSUPRA Compared to Albuterol as Needed in Adults With Mild Asthma (DARWIN)

The purpose of this study is to compare the efficacy and safety of albuterol/budesonide to albuterol in changes in airway inflammation, asthma...

Not yet enrolling
Mild Asthma
Combination Product: Albuterol
Combination Product: Albuterol/Budesonide

Phase 4

AstraZeneca
AstraZeneca

Raleigh, North Carolina, United States and 10 other locations

The purpose of this study is to evaluate dexpramipexole as an add-on oral therapy in participants with inadequately controlled eosinophilic asthma...

Enrolling
Asthma Attack
Asthma; Eosinophilic
Drug: Dexpramipexole Dihydrochloride
Drug: Placebo

Phase 3

Areteia Therapeutics

Raleigh, North Carolina, United States and 209 other locations

To assess the efficacy and safety of tezepelumab in pediatric participants with severe uncontrolled asthma on medium to high-dose inhaled co...

Enrolling
Asthma
Biological: Tezepelumab
Other: Placebo

Phase 3

AstraZeneca
AstraZeneca

Chapel Hill, North Carolina, United States and 105 other locations

trifenatate (FF/UMEC/VI) with inhaled corticosteroids/long-acting beta-2 agonists (ICS/LABA) in adult participants with uncontrolled asthma...

Enrolling
Asthma
Drug: Fluticasone furoate/umeclidinium bromide/vilanterol trifenatate
Drug: Inhaled corticosteroids/long-acting beta-2 agonists

Phase 4

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Raleigh, North Carolina, United States and 67 other locations

To asses effectiveness and safety of tezepelumab in adult and adolescent participants with severe asthma including several under-studied pop...

Active, not recruiting
Asthma
Drug: Tezepelumab

Phase 4

AstraZeneca
AstraZeneca

Chapel Hill, North Carolina, United States and 34 other locations

The purpose of this study is to assess the PD equivalence of the approved asthma combination therapy, BDA, delivered using the proposed repl....

Enrolling
Asthma
Drug: BDA MDI HFO 160/180 μg
Drug: BDA MDI HFA 160/180 μg

Phase 3

AstraZeneca
AstraZeneca

Raleigh, North Carolina, United States and 130 other locations

treatment in children 2 to \<6 years of age with uncontrolled asthma and/or recurrent severe asthmatic wheeze. The study will be conducted i...

Enrolling
Asthma
Wheezing
Drug: Placebo
Drug: Dupilumab

Phase 3

Sanofi
Sanofi

Chapel Hill, North Carolina, United States and 51 other locations

and formoterol fumarate metered dose inhaler relative to budesonide metered dose inhaler in adults and adolescents with inadequately controlled asthma...

Active, not recruiting
Asthma
Drug: BFF MDI 160/9.6 μg BID (320/19.2μg/day)
Drug: BD MDI 160 μg BID (320 μg/day)

Phase 3

AstraZeneca
AstraZeneca

Raleigh, North Carolina, United States and 103 other locations

The purpose of this study is to compare the superiority of CHF 1535 compared to CHF 718 in subjects with asthma on medium or high dose inhal...

Active, not recruiting
Asthma
Drug: Beclomethasone Dipropionate/Formoterol Fumarate
Drug: Beclomethasone Dipropionate

Phase 3

Chiesi
Chiesi

Raleigh, North Carolina, United States and 90 other locations

administered via a dry powder inhaler in adults with uncontrolled asthma at risk of exacerbations, receiving medium -to -high dose inhaled c...

Enrolling
Asthma
Device: Inhaler
Drug: AZD8630

Phase 2

AstraZeneca
AstraZeneca

Raleigh, North Carolina, United States and 112 other locations

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