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Find clinical trials for Asthma in St Louis, MO

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Related conditions:

Pulmonary Eosinophilia
Allergic Rhinitis
Chronic Obstructive Pulmonary Disease
Obstructive Lung Diseases
Rhinitis
Respiration Disorders
Respiratory Tract Diseases

Asthma trials near St Louis, MO, USA:

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma. (EXHALE-2)

This study will assess the efficacy and safety of dexpramipexole as an adjunctive oral therapy in participants with inadequately controlled asthma...

Enrolling
Asthma
Asthma; Eosinophilic
Drug: Placebo
Drug: Dexpramipexole Dihydrochloride

Phase 3

Areteia Therapeutics

Saint Louis, Missouri, United States and 125 other locations

This study will assess the effects of benralizumab on airway dynamics in severe eosinophilic asthma in terms of quantitative computed tomogr...

Active, not recruiting
Asthma
Combination Product: Benralizumab

Phase 4

AstraZeneca
AstraZeneca

Saint Louis, Missouri, United States and 33 other locations

The purpose of this study is to evaluate dexpramipexole as an add-on oral therapy in participants with inadequately controlled eosinophilic asthma...

Enrolling
Asthma Attack
Asthma; Eosinophilic
Drug: Placebo
Drug: Dexpramipexole Dihydrochloride

Phase 3

Areteia Therapeutics

Saint Louis, Missouri, United States and 117 other locations

Primary Objective:To evaluate the long-term safety and tolerability of dupilumab in pediatric patients with asthma who participated in a pre...

Active, not recruiting
Asthma
Drug: Asthma reliever therapies
Drug: Asthma controller therapies (incl. prednisone/prednisolone)

Phase 3

Sanofi
Sanofi

Saint Louis, Missouri, United States and 79 other locations

To asses effectiveness and safety of tezepelumab in adult and adolescent participants with severe asthma including several under-studied pop...

Enrolling
Asthma
Drug: Tezepelumab

Phase 4

AstraZeneca
AstraZeneca

Saint Louis, Missouri, United States and 44 other locations

This study will assess the efficacy and safety of GSK3511294 (Depemokimab) as an adjunctive therapy in participants with severe uncontrolled asthma...

Active, not recruiting
Asthma
Biological: GSK3511294 (Depemokimab)
Biological: Placebo

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Saint Louis, Missouri, United States and 141 other locations

BID using a dry-powder inhaler at one dose level over a 12-week Treatment period in adult participants with uncontrolled moderate-to-severe asthma...

Enrolling
Asthma
Drug: AZD4604
Other: Placebo

Phase 2

AstraZeneca
AstraZeneca

Saint Charles, Missouri, United States and 132 other locations

Locations recently updated

inhaler (eMDPI) compared to ABS eMDPI in decreasing severe clinical asthma exacerbation (CAEs).Secondary Objectives:To evaluate the efficacy...

Enrolling
Asthma
Drug: TEV-56248
Drug: Albuterol sulfate

Phase 3

Teva Pharmaceuticals
Teva Pharmaceuticals

Saint Louis, Missouri, United States and 100 other locations

and safety of Atuliflapon administered once daily over a 12-week treatment period to adult participants with moderate to severe uncontrolled asthma...

Enrolling
Asthma
Drug: Placebo
Drug: Atuliflapon

Phase 2

AstraZeneca
AstraZeneca

Saint Louis, Missouri, United States and 350 other locations

and formoterol fumarate metered dose inhaler relative to budesonide metered dose inhaler in adults and adolescents with inadequately controlled asthma...

Enrolling
Asthma
Drug: BFF MDI 160/9.6 μg BID (320/19.2μg/day)
Drug: BD MDI 160 μg BID (320 μg/day)

Phase 3

AstraZeneca
AstraZeneca

Saint Louis, Missouri, United States and 139 other locations

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