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Find clinical trials for Asthma in Toronto, ON

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Related conditions:

Pulmonary Eosinophilia
Chronic Obstructive Pulmonary Disease
Obstructive Lung Diseases
Allergic Rhinitis
Nasal Polyps
Respiration Disorders
Respiratory Tract Diseases

Asthma trials near Toronto, ON, CAN:

A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA)

in patients ≥ 6 to \< 18 years of age with severe eosinophilic asthma, including a well-documented history of asthma exacerbations ...

Enrolling
Asthma
Drug: Benralizumab
Drug: Placebo

Phase 3

AstraZeneca
AstraZeneca

Burlington, Ontario, Canada and 80 other locations

28-week Phase 3 Efficacy and Safety Study of Tezepelumab in Reducing Oral Corticosteroid Use in Adults with Oral Corticosteroid Dependent Asthma...

Enrolling
Asthma
Other: Placebo
Biological: Tezepelumab

Phase 3

AstraZeneca
AstraZeneca

Ajax, Ontario, Canada and 121 other locations

The purpose of this study is to evaluate the efficacy and safety of verekitug (UPB-101) in participants with severe asthma. The study will e...

Enrolling
Severe Asthma
Drug: Placebo
Drug: Verekitug (UPB-101)

Phase 2

Upstream Bio

Toronto, Ontario, Canada and 47 other locations

Locations recently updated

To assess the efficacy and safety of tezepelumab in pediatric participants with severe uncontrolled asthma on medium to high-dose inhaled co...

Enrolling
Asthma
Biological: Tezepelumab
Other: Placebo

Phase 3

AstraZeneca
AstraZeneca

Burlington, Ontario, Canada and 99 other locations

trifenatate (FF/UMEC/VI) with inhaled corticosteroids/long-acting beta-2 agonists (ICS/LABA) in adult participants with uncontrolled asthma...

Enrolling
Asthma
Drug: Inhaled corticosteroids/long-acting beta-2 agonists
Drug: Fluticasone furoate/umeclidinium bromide/vilanterol trifenatate

Phase 4

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Brampton, Ontario, Canada and 67 other locations

This study will assess the efficacy and safety of GSK3511294 (Depemokimab) as an adjunctive therapy in participants with severe uncontrolled asthma...

Active, not recruiting
Asthma
Biological: GSK3511294 (Depemokimab)
Biological: Placebo

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Burlington, Ontario, Canada and 141 other locations

The study is being conducted to evaluate the effect of 3 dosing regimens of povorcitinib on pulmonary function

Enrolling
Moderate to Severe Asthma
Drug: povorcitinib
Other: placebo

Phase 2

Incyte
Incyte

Toronto, Ontario, Canada and 95 other locations

treatment in children 2 to \<6 years of age with uncontrolled asthma and/or recurrent severe asthmatic wheeze. The study will be conducted i...

Enrolling
Asthma
Wheezing
Drug: Placebo
Drug: Dupilumab

Phase 3

Sanofi
Sanofi

Hamilton, Ontario, Canada and 15 other locations

inhaler (eMDPI) compared to ABS eMDPI in decreasing severe clinical asthma exacerbation (CAEs).Secondary Objectives:To evaluate the efficacy...

Enrolling
Asthma
Drug: TEV-56248
Drug: Albuterol sulfate

Phase 3

Teva Pharmaceuticals
Teva Pharmaceuticals

Etobicoke, Ontario, Canada and 101 other locations

and formoterol fumarate metered dose inhaler relative to budesonide metered dose inhaler in adults and adolescents with inadequately controlled asthma...

Enrolling
Asthma
Drug: BFF MDI 160/9.6 μg BID (320/19.2μg/day)
Drug: BD MDI 160 μg BID (320 μg/day)

Phase 3

AstraZeneca
AstraZeneca

Toronto, Ontario, Canada and 139 other locations

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