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Assess response to pembrolizumab in both primary tumor, normal breast stroma, circulating lymphocytes and serum exosomes in treatme ...
Phase 1
Atlanta, Georgia, United States and 2 other locations
This research is to evaluate the effectiveness of Talazoparib as a potential treatment for metastatic breast cancer with a BRCA 1 o...
Phase 2
Atlanta, Georgia, United States and 6 other locations
monotherapy vs. SOC chemotherapy combined with tocilizumab in in Black and non-Black patients with metastatic triple negative or ER low breast...
Phase 2
Atlanta, Georgia, United States and 4 other locations
therapy as a treatment after surgery for hormone receptor positive breast cancer.The study drugs involved in this study are:* A com...
Phase 2
Atlanta, Georgia, United States and 31 other locations
A randomized, Phase II trial of circulating tumor DNA-guided second line Adjuvant therapy for high Residual risk, Estrogen Receptor positive ...
Phase 2
Atlanta, Georgia, United States and 18 other locations
breast biopsy occurs if biopsy is needed....
Dacula, Georgia, United States and 3 other locations
Choice (TPC) in advanced metastatic or locally recurrent breast cancer (aMBC) patients with no approved alternative therapies avail...
Phase 3
Atlanta, Georgia, United States and 76 other locations
OR in combination with Hormonal Therapy in subjects with HR+, HER2- locally advanced and unresectable (Stage III) or metastatic (Stage IV) breast...
Phase 1
Atlanta, Georgia, United States and 7 other locations
postmenopausal women with locally advanced or metastatic ER+/HER2- breast cancer with an acquired ESR1 mutation and who have diseas...
Phase 2
Atlanta, Georgia, United States and 50 other locations
to anti-HER2-based therapy plus endocrine therapy alone in improving the outcomes of subjects with hormone receptor-positive, HER2+ metastatic breast...
Phase 3
Atlanta, Georgia, United States and 106 other locations
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