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to evaluate safety and efficacy of an antibody drug conjugate U3-1402 (patritumab deruxtecan) in patients with locally advanced or metastatic breast...
Phase 2
Charlotte, North Carolina, United States and 10 other locations
in locally advanced unresectable or metastatic triple-negative breast cancer.The main questions it aims to answer are:to evaluate t...
Phase 2
Charlotte, North Carolina, United States
in patients with estrogen receptor positive/human epidermal growth factor receptor 2 negative (ER+/HER2-) locally advanced or metastatic breast...
Phase 1, Phase 2
Charlotte, North Carolina, United States and 15 other locations
postmenopausal patients with HR-positive, HER2-negative metastatic breast cancer. Pre- and perimenopausal women must receive therap...
Phase 2
Charlotte, North Carolina, United States
to standard endocrine therapy in patients with ER+/HER2 - early breast cancer with intermediate or high risk for disease recurrence...
Phase 3
Charlotte, North Carolina, United States and 692 other locations
RATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone therapy using letrozole may fight breast cancer...
Phase 3
Charlotte, North Carolina, United States and 805 other locations
adjuvant endocrine therapy for patients with ER+/HER2- early breast cancer with intermediate-high or high risk for disease recurren...
Phase 3
Charlotte, North Carolina, United States and 528 other locations
receptor-low/HER2-negative breast cancer....
Phase 3
Charlotte, North Carolina, United States and 338 other locations
This is a Phase Ib/II, open-label, multicenter, randomized umbrella study in participants with breast cancer. Cohort 1 will focus o ...
Phase 1, Phase 2
Charlotte, North Carolina, United States and 27 other locations
In this Phase I trial for subjects with advanced head & neck cancer, breast cancer, soft tissue sarcoma or melanoma all su...
Phase 1
Charlotte, North Carolina, United States and 2 other locations
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