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Find clinical trials for Breast Cancer in Charlotte, NC

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Related conditions:

Triple Negative Breast Cancer
Cancer
Carcinoma
Endometrial Cancer
Squamous Cell Carcinoma of Head and Neck
Non-Small-Cell Lung Carcinoma
Ovarian Cancer

Breast Cancer trials near Charlotte, NC, USA:

A Study of U3-1402 (Patritumab Deruxtecan) in Subjects With Metastatic Breast Cancer

to evaluate safety and efficacy of an antibody drug conjugate U3-1402 (patritumab deruxtecan) in patients with locally advanced or metastatic breast...

Enrolling
Locally Advanced Breast Cancer
Metastatic Breast Cancer
Drug: U3-1402

Phase 2

SCRI Development Innovations

Charlotte, North Carolina, United States and 10 other locations

in locally advanced unresectable or metastatic triple-negative breast cancer.The main questions it aims to answer are:* to evaluate...

Enrolling
Metastatic Triple-Negative Breast Cancer
Drug: Gemcitabine
Drug: Pembrolizumab

Phase 2

Wake Forest University (WFU)
Wake Forest University (WFU)

Charlotte, North Carolina, United States

postmenopausal patients with HR-positive, HER2-negative metastatic breast cancer. Pre- and perimenopausal women must receive therap...

Active, not recruiting
Breast Cancer
Female Breast Carcinoma
Drug: anastrozole
Drug: Palbociclib

Phase 2

Wake Forest University (WFU)
Wake Forest University (WFU)

Charlotte, North Carolina, United States

in patients with estrogen receptor positive/human epidermal growth factor receptor 2 negative (ER+/HER2-) locally advanced or metastatic breast...

Active, not recruiting
Breast Cancer
Drug: ARV-471
Drug: ARV-471 in combination with palbociclib (IBRANCE®)

Phase 1, Phase 2

Arvinas
Arvinas

Charlotte, North Carolina, United States and 15 other locations

RATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone therapy using letrozole may fight breast cancer...

Active, not recruiting
Breast Cancer
Drug: Letrozole
Other: Placebo

Phase 3

National Surgical Adjuvant Breast and Bowel Project Foundation (NSABP)

Charlotte, North Carolina, United States and 805 other locations

to standard endocrine therapy in patients with ER+/HER2 - early breast cancer with intermediate or high risk for disease recurrence...

Enrolling
Breast Cancer, Early Breast Cancer
Drug: Anastrozole
Drug: Exemestane

Phase 3

AstraZeneca
AstraZeneca

Charlotte, North Carolina, United States and 692 other locations

Locations recently updated

adjuvant endocrine therapy for patients with ER+/HER2- early breast cancer with intermediate-high or high risk for disease recurren...

Enrolling
Breast Cancer, Early Breast Cancer
Drug: Exemestane
Drug: Letrozole

Phase 3

AstraZeneca
AstraZeneca

Charlotte, North Carolina, United States and 536 other locations

Locations recently updated

receptor-low/HER2-negative breast cancer....

Enrolling
Breast Cancer
Drug: Epirubicin
Drug: Olaparib

Phase 3

AstraZeneca
AstraZeneca

Charlotte, North Carolina, United States and 343 other locations

This is a Phase Ib/II, open-label, multicenter, randomized umbrella study in participants with breast cancer. Cohort 1 will focus o ...

Enrolling
Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer
Drug: Palbociclib
Drug: Inavolisib

Phase 1, Phase 2

Roche
Roche

Charlotte, North Carolina, United States and 27 other locations

This is a Phase III, randomised, open-label, 2 arm, multicentre, international study assessing the efficacy and safety of Dato-DXd compared with ICC...

Enrolling
Breast Cancer
Drug: Carboplatin
Drug: Nab-paclitaxel

Phase 3

AstraZeneca
AstraZeneca

Charlotte, North Carolina, United States and 273 other locations

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