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to evaluate safety and efficacy of an antibody drug conjugate U3-1402 (patritumab deruxtecan) in patients with locally advanced or metastatic breast...
Phase 2
Charlotte, North Carolina, United States and 10 other locations
in locally advanced unresectable or metastatic triple-negative breast cancer.The main questions it aims to answer are:* to evaluate...
Phase 2
Charlotte, North Carolina, United States
This is a Phase 1/2 dose escalation and cohort expansion study and will assess the safety, tolerability and anti-tumor activity of ARV-471 a ...
Phase 1, Phase 2
Charlotte, North Carolina, United States and 15 other locations
postmenopausal patients with HR-positive, HER2-negative metastatic breast cancer. Pre- and perimenopausal women must receive therap...
Phase 2
Charlotte, North Carolina, United States
works in treating patients with HER2 positive or triple negative breast cancer when image-guided biopsy shows no residual cancer...
Charlotte, North Carolina, United States and 7 other locations
This is a Phase Ib/II, open-label, multicenter, randomized umbrella study in participants with breast cancer. Cohort 1 will focus o ...
Phase 1, Phase 2
Charlotte, North Carolina, United States and 27 other locations
This is a Phase III, randomised, open-label, 2 arm, multicentre, international study assessing the efficacy and safety of Dato-DXd compared with ICC...
Phase 3
Charlotte, North Carolina, United States and 228 other locations
receptor-low/HER2-negative breast cancer....
Phase 3
Charlotte, North Carolina, United States and 351 other locations
RATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone therapy using letrozole may fight breast cancer...
Phase 3
Charlotte, North Carolina, United States and 805 other locations
to standard endocrine therapy in patients with ER+/HER2 - early breast cancer with intermediate or high risk for disease recurrence...
Phase 3
Charlotte, North Carolina, United States and 703 other locations
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