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The purpose of this study is to find out the possible anti-cancer effect of pelareorep in combination with chemotherapy \[paclitaxel\] and a ...
Phase 2
Cleveland, Ohio, United States and 17 other locations
Choice (TPC) in advanced metastatic or locally recurrent breast cancer (aMBC) patients with no approved alternative therapies avail...
Phase 3
Cleveland, Ohio, United States and 76 other locations
A phase 1 study of 68Ga-R11228 and 177Lu-R11228 in breast cancer....
Phase 1
Cleveland, Ohio, United States and 6 other locations
participants with metastatic or locally advanced Hormone Receptor (HR) positive and Human Epidermal Growth Factor Receptor (HER)2-negative breast...
Phase 1, Phase 2
Cleveland, Ohio, United States and 22 other locations
This study will look to establish the recommended biologic dose of AE37 in combination with pembrolizumab that will enhance the tumor-specif ...
Phase 2
Cleveland, Ohio, United States and 5 other locations
(Part 2). The primary purpose of Dose Expansion (Part 2) is to assess the antitumor activity of BB-1701 at RD in the selected population(s) of breast...
Phase 2
Cleveland, Ohio, United States and 48 other locations
with inoperable or metastatic HR-positive, HER2- negative breast cancer who have been treated with one or two prior lines of...
Phase 3
Cleveland, Ohio, United States and 166 other locations
with anti-HER2 antibodies in patients with HER2-negative invasive breast cancer who have abnormal HER2 signaling activity determine...
Phase 2
Cleveland, Ohio, United States and 42 other locations
The goal of this clinical trial is to assess the efficacy of DB-1303/BNT323 compared with investigator's choice chemotherapy in terms of progression-...
Phase 3
Akron, Ohio, United States and 260 other locations
This study is designed to compare the anti-tumor activity as well as the safety and efficacy of DS-8201a versus T-DM1 in HER2-positive, unre ...
Phase 3
Cleveland, Ohio, United States and 163 other locations
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