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Choice (TPC) in advanced metastatic or locally recurrent breast cancer (aMBC) patients with no approved alternative therapies avail...
Phase 3
Cleveland, Ohio, United States and 78 other locations
The purpose of this study is to find out the possible anti-cancer effect of pelareorep in combination with chemotherapy \[paclitaxel\] and a ...
Phase 2
Cleveland, Ohio, United States and 17 other locations
The goal of this clinical trial is to assess the efficacy of DB-1303/BNT323 compared with investigator's choice chemotherapy in terms of progression-...
Phase 3
Akron, Ohio, United States and 257 other locations
with inoperable or metastatic HR-positive, HER2- negative breast cancer who have been treated with one or two prior lines of...
Phase 3
Cleveland, Ohio, United States and 166 other locations
and demonstrate efficacy in patients with advanced triple-negative breast cancer.This study will take place in two parts. Stage 1 w...
Phase 2
Cleveland, Ohio, United States and 5 other locations
The primary objective of this trial is to evaluate ovarian suppression following treatment with ZOLADEX 10.8 mg by luteinizing hormone (LH) within ea...
Phase 1
Cleveland, Ohio, United States and 22 other locations
versus T-DM1 in HER2-positive, unresectable and/or metastatic breast cancer subjects previously treated with trastuzumab and taxane....
Phase 3
Cleveland, Ohio, United States and 163 other locations
in participants with intermediate-risk HR+/HER2- early-stage breast cancer. Based on ctDNA test results, participants will either s...
Cleveland, Ohio, United States and 48 other locations
RATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone therapy using letrozole may fight breast cancer...
Phase 3
Cleveland, Ohio, United States and 805 other locations
with anti-HER2 antibodies in patients with HER2-negative invasive breast cancer who have abnormal HER2 signaling activity determine...
Phase 2
Cleveland, Ohio, United States and 42 other locations
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