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Choice (TPC) in advanced metastatic or locally recurrent breast cancer (aMBC) patients with no approved alternative therapies avail...
Phase 3
Cleveland, Ohio, United States and 35 other locations
The purpose of this study is to find out the possible anti-cancer effect of pelareorep in combination with chemotherapy \[paclitaxel\] and a ...
Phase 2
Cleveland, Ohio, United States and 17 other locations
participants with metastatic or locally advanced Hormone Receptor (HR) positive and Human Epidermal Growth Factor Receptor (HER)2-negative breast...
Phase 1, Phase 2
Cleveland, Ohio, United States and 22 other locations
This study will compare DS 8201a to standard treatment.Participants must have HER2 breast cancer that has been treated before.Their ...
Phase 3
Cleveland, Ohio, United States and 226 other locations
This study will look to establish the recommended biologic dose of AE37 in combination with pembrolizumab that will enhance the tumor-specif ...
Phase 2
Cleveland, Ohio, United States and 5 other locations
(Part 2). The primary purpose of Dose Expansion (Part 2) is to assess the antitumor activity of BB-1701 at RD in the selected population(s) of breast...
Phase 2
Cleveland, Ohio, United States and 30 other locations
A study to learn about a new medicine called ARV-471 (PF-07850327) in people who have advanced metastatic breast cancer....
Phase 3
Cleveland, Ohio, United States and 446 other locations
The goal of this clinical trial is to assess the efficacy of DB-1303/BNT323 compared with investigator's choice chemotherapy in terms of progression-...
Phase 3
Akron, Ohio, United States and 184 other locations
with inoperable or metastatic HR-positive, HER2- negative breast cancer who have been treated with one or two prior lines of...
Phase 3
Cleveland, Ohio, United States and 166 other locations
for the treatment of participants with metastatic HER2-positive breast cancer who have progressed on, or are intolerant to, previou...
Phase 3
Cleveland, Ohio, United States and 40 other locations
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