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(ICI) on on 3-year Event Free Survival (EFS), in women with residual hormone receptor negative, HER2-negative ("triple negative") resectable breast...
Phase 2
Dallas, Texas, United States and 3 other locations
This research study is studying a drug combination of nivolumab and ipilimumab as a possible treatment for hypermutated HER2 negative breast ...
Phase 2
Dallas, Texas, United States and 2 other locations
The goal of this clinical trial is to assess the efficacy of DB-1303/BNT323 compared with investigator's choice chemotherapy in terms of progression-...
Phase 3
Dallas, Texas, United States and 3 other locations
Choice (TPC) in advanced metastatic or locally recurrent breast cancer (aMBC) patients with no approved alternative therapies avail...
Phase 3
Dallas, Texas, United States and 7 other locations
To evaluate the efficacy of cryoablation without lumpectomy and its impact on local and distant recurrence of early stage breast cancer...
Plano, Texas, United States and 18 other locations
DESTINY-Breast07 will investigate the safety, tolerability, and anti-tumour activity of trastuzumab deruxtecan (T-DXd) in combination with o ...
Phase 1, Phase 2
Fort Worth, Texas, United States and 71 other locations
This study will be conducted in patients with metastatic breast cancer who have specific Fibroblast Growth Factor Receptor gene abn...
Phase 2
Dallas, Texas, United States and 36 other locations
The standard treatment for women with stage I, II, and III triple-negative breast cancer (TNBC) includes chemotherapy and surgery, ...
Phase 2
Dallas, Texas, United States and 8 other locations
This study will compare DS 8201a to standard treatment.Participants must have HER2 breast cancer that has been treated before.Their ...
Phase 3
Dallas, Texas, United States and 226 other locations
A Global, Phase 2 Study of ARX788 in HER2-positive Metastatic Breast Cancer Patients who were previously treated with T-DXd...
Phase 2
Dallas, Texas, United States and 57 other locations
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