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kinesin oral molecular degrader, administered as monotherapy or in combination with fulvestrant in adults with advanced or metastatic breast ...
Phase 1
Dallas, Texas, United States and 7 other locations
(ICI) on on 3-year Event Free Survival (EFS), in women with residual hormone receptor negative, HER2-negative ("triple negative") resectable breast...
Phase 2
Dallas, Texas, United States and 3 other locations
This research study is studying a drug combination of nivolumab and ipilimumab as a possible treatment for hypermutated HER2 negative breast ...
Phase 2
Dallas, Texas, United States and 2 other locations
The standard treatment for women with stage I, II, and III triple-negative breast cancer (TNBC) includes chemotherapy and surgery, ...
Phase 2
Dallas, Texas, United States and 8 other locations
growth factor 2 positive (HER2+) locally advanced or metastatic breast cancer. The main goals of this study are to:* Learn how well...
Phase 2
Dallas, Texas, United States and 7 other locations
Choice (TPC) in advanced metastatic or locally recurrent breast cancer (aMBC) patients with no approved alternative therapies avail...
Phase 3
Dallas, Texas, United States and 78 other locations
DESTINY-Breast07 will investigate the safety, tolerability, and anti-tumour activity of trastuzumab deruxtecan (T-DXd) in combination with o ...
Phase 1, Phase 2
Fort Worth, Texas, United States and 71 other locations
A Global, Phase 2 Study of ARX788 in HER2-positive Metastatic Breast Cancer Patients who were previously treated with T-DXd...
Phase 2
Dallas, Texas, United States and 32 other locations
DESTINY-Breast 08 will investigate the safety, tolerability, PK and preliminary anti-tumour activity of T-DXd in combination with other ther ...
Phase 1
Fort Worth, Texas, United States and 36 other locations
effective, when combined with chemotherapy, in treating people who has Human Epidermal Growth Factor Receptor 2 (HER2)-positive, early-stage breast...
Phase 2
Dallas, Texas, United States and 25 other locations
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