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Find clinical trials for Breast Cancer in London, England

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Related conditions:

Triple Negative Breast Cancer
Cancer
Carcinoma
Endometrial Cancer
Squamous Cell Carcinoma of Head and Neck
Non-Small-Cell Lung Carcinoma
Ovarian Cancer

Breast Cancer trials near London, England, GBR:

Crizotinib in Lobular Breast, Diffuse Gastric and Triple Negative Lobular Breast Cancer or CDH1-mutated Solid Tumours (ROLo)

The purpose of this study is to find out how effective the combination of crizotinib and fulvestrant is in shrinking lobular breast cancer...

Active, not recruiting
Gastric Cancer
Lobular Breast Carcinoma
Drug: Crizotinib Oral Capsule [Xalkori]
Drug: Fulvestrant 50 MG/ML Prefilled Syringe [Faslodex or generic]

Phase 2

Royal Marsden NHS Foundation Trust

London, United Kingdom and 4 other locations

adjuvant systemic treatment instead of adjuvant chemotherapy followed by endocrine therapy in older patients with stage II-III ER+/HER2- early breast...

Active, not recruiting
Breast Cancer Stage II
Breast Cancer Stage III
Drug: doxorubicin/cyclophosphamide
Drug: Docetaxel / cyclophosphamide

Phase 2

European Organisation for Research and Treatment of Cancer (EORTC)

London, United Kingdom and 72 other locations

This neoadjuvant trial for patients with TNBC and/or gBRCA breast cancer, aims to investigate the safety and efficacy (improvement ...

Enrolling
Breast Cancer
Drug: Paclitaxel and Carboplatin
Drug: Olaparib

Phase 2, Phase 3

NHS Foundation Trust
NHS Foundation Trust

London, United Kingdom and 29 other locations

This study will compare DS 8201a to standard treatment.Participants must have HER2 breast cancer that has been treated before.Their ...

Active, not recruiting
Breast Cancer
Drug: Trastuzumab
Drug: Trastuzumab deruxtecan

Phase 3

Daiichi Sankyo
Daiichi Sankyo

London, Greater London, United Kingdom and 226 other locations

DESTINY-Breast07 will investigate the safety, tolerability, and anti-tumour activity of trastuzumab deruxtecan (T-DXd) in combination with o ...

Active, not recruiting
Metastatic Breast Cancer
Drug: Paclitaxel
Drug: Tucatinib

Phase 1, Phase 2

AstraZeneca
AstraZeneca

Buckhurst Hill, United Kingdom and 71 other locations

The aim of this study is to assess the rates of circulating tumour DNA (ctDNA) in patients treated with surgery for stage 1 breast cancer...

Enrolling
Breast Cancer
Diagnostic Test: ctDNA
Royal Marsden NHS Foundation Trust

London, United Kingdom and 1 other location

This study will be conducted in patients with metastatic breast cancer who have specific Fibroblast Growth Factor Receptor gene abn...

Active, not recruiting
Metastatic Breast Cancer
FGFR 1 High Amplification
Drug: Futibatinib
Drug: Futibatinib plus Fulvestrant

Phase 2

Taiho Pharma
Taiho Pharma

London, England, United Kingdom and 36 other locations

A Phase 1 Dose Escalation and Expansion Study of AZD9833 Alone or in Combination in Women with ER Positive, HER2 Negative Advanced Breast Ca...

Active, not recruiting
ER+ HER2- Advanced Breast Cancer
Drug: AZD9833 with abemaciclib
Drug: AZD9833 with ribociclib

Phase 1

AstraZeneca
AstraZeneca

London, United Kingdom and 16 other locations

be investigating how effective the combination is for a subgroup of breast cancer patients whose cancer expresses the andr...

Enrolling
Locally Advanced Breast Cancer
HER2-positive Breast Cancer
Drug: Avelumab
Drug: Palbociclib

Phase 1

Royal Marsden NHS Foundation Trust

London, United Kingdom and 7 other locations

A study to learn about a new medicine called ARV-471 (PF-07850327) in people who have advanced metastatic breast cancer....

Enrolling
Advanced Breast Cancer
Drug: Fulvestrant
Drug: ARV-471

Phase 3

Pfizer
Pfizer

London, London, CITY OF, United Kingdom and 324 other locations

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