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Find clinical trials for Breast Cancer in London, England

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Related conditions:

Triple Negative Breast Cancer
Cancer
Carcinoma
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Squamous Cell Carcinoma of Head and Neck
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Breast Cancer trials near London, England, GBR:

Effect of Capivasertib on ctDNA in ER Positive Breast Cancer (CaptAin)

There is growing evidence that cancer DNA (called circulating tumour DNA - ctDNA) in the blood is often an early sign that the cancer...

Not yet enrolling
Breast Cancer
Oestrogen Receptor Positive Breast Cancer
Drug: Capivasertib

Phase 2

Imperial College London
Imperial College London

London, United Kingdom

The purpose of this study is to find out how effective the combination of crizotinib and fulvestrant is in shrinking lobular breast cancer...

Active, not recruiting
Gastric Cancer
Lobular Breast Carcinoma
Drug: Crizotinib Oral Capsule [Xalkori]
Drug: Fulvestrant 50 MG/ML Prefilled Syringe [Faslodex or generic]

Phase 2

Royal Marsden NHS Foundation Trust

London, United Kingdom and 4 other locations

This prospective, multicenter, 1:1 randomized, controlled trial is designed to evaluate the safety and effectiveness of the Breast Cancer...

Enrolling
Breast Cancer Female
Device: Breast Cancer Locator (BCL) guided partial mastectomy
Device: Wire Localized (WL) partial mastectomy
CairnSurgical

London, United Kingdom and 25 other locations

adjuvant systemic treatment instead of adjuvant chemotherapy followed by endocrine therapy in older patients with stage II-III ER+/HER2- early breast...

Active, not recruiting
Breast Cancer Stage II
Breast Cancer Stage III
Drug: Palbociclib
Drug: Docetaxel / cyclophosphamide

Phase 2

European Organisation for Research and Treatment of Cancer (EORTC)

London, United Kingdom and 72 other locations

This neoadjuvant trial for patients with TNBC and/or gBRCA breast cancer, aims to investigate the safety and efficacy (improvement ...

Enrolling
Breast Cancer
Drug: Paclitaxel and Carboplatin
Drug: Olaparib

Phase 2, Phase 3

NHS Foundation Trust
NHS Foundation Trust

London, United Kingdom and 29 other locations

be investigating how effective the combination is for a subgroup of breast cancer patients whose cancer expresses the andr...

Enrolling
Locally Advanced Breast Cancer
HER2-positive Breast Cancer
Drug: Avelumab
Drug: Palbociclib

Phase 1

Royal Marsden NHS Foundation Trust

London, United Kingdom and 6 other locations

This study will be conducted in patients with metastatic breast cancer who have specific Fibroblast Growth Factor Receptor gene abn...

Active, not recruiting
Metastatic Breast Cancer
FGFR 1 High Amplification
Drug: Futibatinib
Drug: Futibatinib plus Fulvestrant

Phase 2

Taiho Pharma
Taiho Pharma

London, England, United Kingdom and 36 other locations

DESTINY-Breast07 will investigate the safety, tolerability, and anti-tumour activity of trastuzumab deruxtecan (T-DXd) in combination with o ...

Active, not recruiting
Metastatic Breast Cancer
Drug: Tucatinib
Drug: Durvalumab

Phase 1, Phase 2

AstraZeneca
AstraZeneca

Buckhurst Hill, United Kingdom and 71 other locations

The aim of this study is to assess the rates of circulating tumour DNA (ctDNA) in patients treated with surgery for stage 1 breast cancer...

Enrolling
Breast Cancer
Diagnostic Test: ctDNA
Royal Marsden NHS Foundation Trust

London, United Kingdom and 1 other location

A Phase 1 Dose Escalation and Expansion Study of AZD9833 Alone or in Combination in Women with ER Positive, HER2 Negative Advanced Breast Ca...

Active, not recruiting
ER+ HER2- Advanced Breast Cancer
Drug: AZD9833 with palbociclib
Drug: AZD9833 with capivasertib

Phase 1

AstraZeneca
AstraZeneca

London, United Kingdom and 16 other locations

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