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This trial studies the efficacy and safety of cryoablation in patients with low risk, early stage breast cancer. Cryoablation is a ...
Saint Louis, Missouri, United States
to evaluate safety and efficacy of an antibody drug conjugate U3-1402 (patritumab deruxtecan) in patients with locally advanced or metastatic breast...
Phase 2
Saint Louis, Missouri, United States and 10 other locations
The purpose of this study is to find out the possible anti-cancer effect of pelareorep in combination with chemotherapy \[paclitaxel\] and a ...
Phase 2
Saint Louis, Missouri, United States and 17 other locations
endocrine therapy in participants with node-positive, Estrogen Receptor-positive (ER+), Human Epidermal Growth Factor-2 negative (HER2-) early breast...
Phase 3
Saint Louis, Missouri, United States and 13 other locations
The Phase 2 part of the trial will evaluate the efficacy and safety of the various combinations in patients with ER+/HER2- advanced/metastatic breast...
Phase 1, Phase 2
Saint Louis, Missouri, United States and 115 other locations
OR in combination with Hormonal Therapy in subjects with HR+, HER2- locally advanced and unresectable (Stage III) or metastatic (Stage IV) breast...
Phase 1
Saint Louis, Missouri, United States and 4 other locations
to anti-HER2-based therapy plus endocrine therapy alone in improving the outcomes of subjects with hormone receptor-positive, HER2+ metastatic breast...
Phase 3
Saint Louis, Missouri, United States and 117 other locations
A Global, Phase 2 Study of ARX788 in HER2-positive Metastatic Breast Cancer Patients who were previously treated with T-DXd...
Phase 2
Saint Louis, Missouri, United States and 63 other locations
postmenopausal women with locally advanced or metastatic ER+/HER2- breast cancer with an acquired ESR1 mutation and who have diseas...
Phase 2
Saint Louis, Missouri, United States and 50 other locations
with pathology-confirmed HR-positive/HER2-negative metastatic breast cancer (MBC) following progression on or after at least two pr...
Phase 2
Saint Louis, Missouri, United States and 21 other locations
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