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Find clinical trials for Breast Cancer in Toronto, ON

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Related conditions:

Triple Negative Breast Cancer
Cancer
Carcinoma
Endometrial Cancer
Squamous Cell Carcinoma of Head and Neck
Non-Small-Cell Lung Carcinoma
Ovarian Cancer

Breast Cancer trials near Toronto, ON, CAN:

Breast Cancer Locator Guided vs. Wire Localized Partial Mastectomy for Breast Cancer

This prospective, multicenter, 1:1 randomized, controlled trial is designed to evaluate the safety and effectiveness of the Breast Cancer...

Enrolling
Breast Cancer Female
Device: Breast Cancer Locator (BCL) guided partial mastectomy
Device: Wire Localized (WL) partial mastectomy
CairnSurgical

Toronto, Ontario, Canada and 25 other locations

This study will be conducted in patients with metastatic breast cancer who have specific Fibroblast Growth Factor Receptor gene abn...

Active, not recruiting
Metastatic Breast Cancer
FGFR 1 High Amplification
Drug: Futibatinib
Drug: Futibatinib plus Fulvestrant

Phase 2

Taiho Pharma
Taiho Pharma

Toronto, Canada and 36 other locations

DESTINY-Breast07 will investigate the safety, tolerability, and anti-tumour activity of trastuzumab deruxtecan (T-DXd) in combination with o ...

Active, not recruiting
Metastatic Breast Cancer
Drug: Tucatinib
Drug: Durvalumab

Phase 1, Phase 2

AstraZeneca
AstraZeneca

Toronto, Canada and 71 other locations

The proposed study will evaluate the safety and efficacy of XRT followed by systemic therapy among patients with HER2+ metastatic breast cancer...

Enrolling
HER2-positive Breast Cancer
LMD
Drug: Capecitabine
Radiation: Brain & Spinal Radiation

Phase 2

Sunnybrook Health Sciences Centre

Toronto, Ontario, Canada and 1 other location

to see if it can be a possible treatment for advanced metastatic breast cancer. This type of cancer would have spread from...

Enrolling
Breast Cancer
Drug: vepdegestrant
Drug: PF-07220060

Phase 1, Phase 2

Pfizer
Pfizer

Toronto, Ontario, Canada and 32 other locations

look at the efficacy and safety of trastuzumab deruxtecan (T-DXd) in a neoadjuvant setting, in high-risk, HER2-positive early non-metastatic breast...

Active, not recruiting
HER2-positive Early Breast Cancer
Breast Cancer
Drug: Pertuzumab
Drug: Paclitaxel

Phase 3

AstraZeneca
AstraZeneca

Toronto, Ontario, Canada and 147 other locations

postmenopausal women with locally advanced or metastatic ER+/HER2- breast cancer with an acquired ESR1 mutation and who have diseas...

Active, not recruiting
Locally Advanced or Metastatic Breast Cancer
Drug: Lasofoxifene
Drug: Fulvestrant

Phase 2

Sermonix Pharmaceuticals

Toronto, Ontario, Canada and 50 other locations

The goal of this clinical trial is to assess the efficacy of DB-1303/BNT323 compared with investigator's choice chemotherapy in terms of progression-...

Enrolling
Metastatic Breast Cancer
Drug: Paclitaxel
Drug: Nab-paclitaxel

Phase 3

DualityBio

Toronto, Ontario, Canada and 126 other locations

A study to learn about a new medicine called ARV-471 (PF-07850327) in people who have advanced metastatic breast cancer....

Enrolling
Advanced Breast Cancer
Drug: ARV-471
Drug: Fulvestrant

Phase 3

Pfizer
Pfizer

Toronto, Ontario, Canada and 324 other locations

medicines for the potential treatment of advanced or metastatic breast cancer.This study is seeking participants who have breast...

Enrolling
Breast Cancer
Drug: Abemaciclib
Drug: ARV-471

Phase 1, Phase 2

Pfizer
Pfizer

Toronto, Ontario, Canada and 44 other locations

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