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Find clinical trials for Chronic Lymphocytic Leukemia in Cincinnati, OH

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Related conditions:

B-Cell Chronic Lymphocytic Leukemia
Leukemia
Lymphoid Leukemia
Lymphoma
B-Cell Lymphoma
Mantle-Cell Lymphoma
Non-Hodgkin Lymphoma

Chronic Lymphocytic Leukemia trials near Cincinnati, OH, USA:

A Study to Customize Ibrutinib Treatment Regimens for Participants With Previously Untreated Chronic Lymphocytic Leukemia (TAILOR)

The purpose of this study is to evaluate the efficacy and safety of ibrutinib + venetoclax (I+V) and ibrutinib monotherapy regimens in which dosing o...

Enrolling
Small Lymphocytic Lymphoma
Leukemia, Lymphocytic, Chronic, B-Cell
Drug: Venetoclax
Drug: Ibrutinib

Phase 2

Janssen (J&J Innovative Medicine)
Janssen (J&J Innovative Medicine)

Cincinnati, Ohio, United States of America and 47 other locations

This is a study for patients with chronic lymphocytic leukemia (CLL) or small lymphocytic leukemia (SLL)...

Active, not recruiting
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: Idelalisib
Drug: Bendamustine

Phase 3

Loxo Oncology
Loxo Oncology

Cincinnati, Ohio, United States and 231 other locations

The purpose of this study is to compare the efficacy and safety of fixed duration pirtobruitinib (LOXO-305) with VR (Arm A) compared to VR alone (Arm...

Enrolling
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: Venetoclax
Drug: Rituximab

Phase 3

Loxo Oncology
Loxo Oncology

Cincinnati, Ohio, United States of America and 216 other locations

A Phase 1 first-in-human dose-escalation and dose-expansion study of BMF-219, an oral covalent menin inhibitor, in adult patients with AML, ALL (with...

Enrolling
Acute Mixed-Phenotype Leukemia
Small Lymphocytic Lymphoma
Drug: BMF-219

Phase 1

Biomea Fusion

Cincinnati, Ohio, United States and 40 other locations

for the treatment of adults with Diffuse Large B-Cell Lymphoma and Chronic Lymphocytic Leukemia. Participants must be rela...

Enrolling
Chronic Lymphocytic Leukemia
Non Hodgkin Lymphoma
Drug: acalabrutinib
Drug: KRT-232

Phase 1, Phase 2

Kartos Therapeutics
Kartos Therapeutics

Cincinnati, Ohio, United States and 44 other locations

attaches to a protein (called ROR 1) that is found on hematologic tumor cells. ROR1 has been shown to play a role in cell signaling that cause leukemia...

Active, not recruiting
Small Lymphocytic Lymphoma
B-cell Chronic Lymphocytic Leukemia
Drug: Cirmtuzumab (2-16 kg/mg) plus Ibrutinib
Drug: Cirmtuzumab (RDR) plus ibrutinib

Phase 1, Phase 2

Oncternal Therapeutics

Cincinnati, Ohio, United States and 11 other locations

with obinutuzumab (Arm B) for the treatment of previously untreated chronic lymphocytic leukemia (CLL). Secondary objectiv...

Active, not recruiting
Chronic Lymphocytic Leukemia
Drug: Acalabrutinib
Drug: Chlorambucil

Phase 3

Acerta Pharma
Acerta Pharma

Blue Ash, Ohio, United States and 154 other locations

This is a first-in-human Phase 1a/1b multicenter, open-label oncology study designed to evaluate the safety and anti-cancer activity of NX-2127 in pa...

Active, not recruiting
Small Lymphocytic Lymphoma (SLL)
Chronic Lymphocytic Leukemia (CLL)
Drug: NX-2127

Phase 1

Nurix Therapeutics

Cincinnati, Ohio, United States and 15 other locations

This is a first-in-human Phase 1a/1b multicenter, open-label study designed to evaluate the safety and anti-cancer activity of NX-5948 in patients wi...

Enrolling
Small Lymphocytic Lymphoma (SLL)
Chronic Lymphocytic Leukemia (CLL)
Drug: NX-5948

Phase 1

Nurix Therapeutics

Cincinnati, Ohio, United States and 24 other locations

This is a Phase 1, multi-center, open-label study with a dose-escalation phase (Phase 1a) and a cohort expansion phase (Phase 1b), to evaluate the sa...

Enrolling
Small Lymphocytic Lymphoma
Acute Lymphocytic Leukemia
Drug: LP-118

Phase 1

Newave Pharmaceutical

Cincinnati, Ohio, United States and 7 other locations

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