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Find clinical trials for Chronic Lymphocytic Leukemia in Cleveland, OH

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Related conditions:

B-Cell Chronic Lymphocytic Leukemia
Leukemia
Lymphoid Leukemia
Lymphoma
B-Cell Lymphoma
Mantle-Cell Lymphoma
Non-Hodgkin Lymphoma

Chronic Lymphocytic Leukemia trials near Cleveland, OH, USA:

A Study of Acalabrutinib Plus Venetoclax Versus Venetoclax Plus Obinutuzumab in Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (MAJIC)

A study of acalabrutinib plus venetoclax (AV) versus venetoclax plus obinutuzumab (VO) in previously untreated chronic lymphocytic ...

Active, not recruiting
Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Drug: Venetoclax
Drug: Obinutuzumab

Phase 3

AstraZeneca
AstraZeneca

Cleveland, Ohio, United States and 40 other locations

This is a Phase 1/2, open-label, multicenter study to determine the efficacy and safety of JCAR017 in adult subjects with relapsed or refractory CLL...

Enrolling
Lymphoma, Small Lymphocytic
Leukemia, Lymphocytic, Chronic, B-Cell
Biological: JCAR017 (lisocabtagene maraleucel) + venetoclax
Biological: JCAR017 (lisocabtagene maraleucel) + ibrutinib

Phase 1, Phase 2

Juno Therapeutics

Cleveland, Ohio, United States and 69 other locations

This phase I trial studies the side effects and best dose of romidepsin in treating patients with lymphoma, chronic lymphocytic leukemia...

Active, not recruiting
Recurrent Chronic Lymphocytic Leukemia
Refractory Chronic Lymphocytic Leukemia
Other: Pharmacological Study
Drug: Romidepsin

Phase 1

National Cancer Institute (NCI)
National Cancer Institute (NCI)

Cleveland, Ohio, United States and 11 other locations

A Phase 1 first-in-human dose-escalation and dose-expansion study of BMF-219, an oral covalent menin inhibitor, in adult patients with AML, ALL (with...

Enrolling
Acute Mixed-Phenotype Leukemia
Small Lymphocytic Lymphoma
Drug: BMF-219

Phase 1

Biomea Fusion

Cleveland, Ohio, United States and 40 other locations

This is an open-label, multi-center Phase 1/2 study of oral LOXO-305 (pirtobrutinib) in patients with CLL/SLL and NHL who have failed or are intolera...

Active, not recruiting
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: Venetoclax
Drug: Rituximab

Phase 1, Phase 2

Loxo Oncology
Loxo Oncology

Cleveland, Ohio, United States and 55 other locations

Study to Assess the Safety, Tolerability and Efficacy of MB-106 in Patients with Relapsed or Refractory B-Cell NHL or CLL

Enrolling
Chronic Lymphoid Leukemia in Relapse
Small Lymphocytic Lymphoma, Relapsed
Biological: MB-106

Phase 1, Phase 2

Mustang Bio

Cleveland, Ohio, United States and 5 other locations

A phase 1/2a, first-in-human trial to evaluate the safety and tolerability of LAVA-051 in patients with relapsed or refractory Chronic Lymphocytic...

Active, not recruiting
Chronic Lymphocytic Leukemia
Acute Myeloid Leukemia
Biological: Interleukin 2
Biological: LAVA-051

Phase 1, Phase 2

Lava Therapeutics

Cleveland, Ohio, United States and 13 other locations

This is a first-in-human Phase 1a/1b multicenter, open-label study designed to evaluate the safety and anti-cancer activity of NX-5948 in patients wi...

Enrolling
Small Lymphocytic Lymphoma (SLL)
Chronic Lymphocytic Leukemia (CLL)
Drug: NX-5948

Phase 1

Nurix Therapeutics

Cleveland, Ohio, United States and 24 other locations

in patients with relapsed/refractory non-Hodgkin lymphoma (NHL), chronic lymphocytic leukemia (CLL) or B cell acute lympho...

Enrolling
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Biological: NKX019

Phase 1

Nkarta

Cleveland, Ohio, United States and 6 other locations

Assess the safety and tolerability, identify dose-limiting toxicities (DLT) and determine the maximum tolerated dose (MTD) / recommended phase 2 dose...

Enrolling
CLL/SLL
Drug: APG2575

Phase 1

Ascentage Pharma Group
Ascentage Pharma Group

Cleveland, Ohio, United States and 8 other locations

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