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To assess the efficacy and safety of pirtobrutinib in participants with CLL/SLL who have progressed on first-line treatment with acalabrutinib.
Phase 2
Columbus, Ohio, United States and 12 other locations
particular disorder or dysfunction (asymptomatic) who have high-risk chronic lymphocytic leukemia or small lymphocytic...
Phase 2
Columbus, Ohio, United States
This study is evaluating the safety and efficacy of the combined use of acalabrutinib and ACP-319, for the treatment of chronic lymphocytic...
Phase 1
Columbus, Ohio, United States and 2 other locations
This study is evaluating the safety and efficacy of a new BTK inhibitor, acalabrutinib, for the treatment of chronic lymphocytic le...
Phase 1, Phase 2
Columbus, Ohio, United States and 11 other locations
treating patients with relapsed, refractory, or previously untreated chronic lymphocytic leukemia, small lymphocytic...
Phase 2
Columbus, Ohio, United States
patient populations.CAP-100 is expected to prevent the migration of leukemia cells to and their survival in lymphoid niches as well as to el...
Phase 1
Columbus, Ohio, United States and 5 other locations
This study is designed to evaluate progression-free survival (PFS) endpoint for acalabrutinib versus (vs) ibrutinib in previously treated chronic...
Phase 3
Columbus, Ohio, United States and 130 other locations
objective of this study is to compare the efficacy of sonrotoclax plus zanubrutinib versus venetoclax plus obinutuzumab in participants with chronic...
Phase 3
Columbus, Ohio, United States and 213 other locations
The purpose of this study is to compare the efficacy and safety of pirtobruitinib (LOXO-305) to ibrutinib in participants with CLL/SLL. Participants...
Phase 3
Columbus, Ohio, United States and 179 other locations
This is a Phase 1/2, open-label, multicenter study to determine the efficacy and safety of JCAR017 in adult subjects with relapsed or refractory CLL...
Phase 1, Phase 2
Columbus, Ohio, United States and 79 other locations
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