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Find clinical trials for Chronic Lymphocytic Leukemia in Columbus, OH

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Related conditions:

B-Cell Chronic Lymphocytic Leukemia
Leukemia
Lymphoid Leukemia
Lymphoma
B-Cell Lymphoma
Mantle-Cell Lymphoma
Non-Hodgkin Lymphoma

Chronic Lymphocytic Leukemia trials near Columbus, OH, USA:

Ibrutinib as an Immune Modulating Agent for Patients With Asymptomatic, High-risk CLL/SLL Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

particular disorder or dysfunction (asymptomatic) who have high-risk chronic lymphocytic leukemia or small lymphocytic...

Active, not recruiting
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Other: Quality-of-Life Assessment
Biological: Pneumococcal 13-valent Conjugate Vaccine

Phase 2

Jennifer Woyach

Columbus, Ohio, United States

This study is evaluating the safety and efficacy of the combined use of acalabrutinib and ACP-319, for the treatment of chronic lymphocytic...

Active, not recruiting
Chronic Lymphocytic Leukemia
Drug: ACP-319
Drug: acalabrutinib

Phase 1

Acerta Pharma
Acerta Pharma

Columbus, Ohio, United States and 2 other locations

This study is evaluating the safety and efficacy of a new BTK inhibitor, acalabrutinib, for the treatment of chronic lymphocytic le...

Active, not recruiting
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: Acalabrutinib

Phase 1, Phase 2

Acerta Pharma
Acerta Pharma

Columbus, Ohio, United States and 11 other locations

objective of this study is to compare the efficacy of sonrotoclax plus zanubrutinib versus venetoclax plus obinutuzumab in participants with chronic...

Enrolling
CLL
Drug: Zanubrutinib
Drug: Sonrotoclax

Phase 3

BeiGene
BeiGene

Columbus, Ohio, United States and 81 other locations

treating patients with relapsed, refractory, or previously untreated chronic lymphocytic leukemia, small lymphocytic...

Active, not recruiting
Stage IV Small Lymphocytic Lymphoma
Recurrent Small Lymphocytic Lymphoma
Biological: MOR00208
Other: Correlative Studies

Phase 2

The Ohio State University
The Ohio State University

Columbus, Ohio, United States

This phase I trial studies the side effects and best dose of selinexor when given together with ibrutinib in treating patients with chronic ...

Active, not recruiting
Recurrent Small Lymphocytic Lymphoma
Refractory Chronic Lymphocytic Leukemia
Other: Pharmacological Study
Drug: Selinexor

Phase 1

Jennifer Woyach

Columbus, Ohio, United States and 1 other location

with Obinutuzumab in subjects with relapsed or refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma....

Active, not recruiting
Lymphoma, Non-Hodgkin
Drug: CC-99282
Drug: Obinutuzumab

Phase 1

Celgene
Celgene

Columbus, Ohio, United States and 14 other locations

This study is designed to evaluate progression-free survival (PFS) endpoint for acalabrutinib versus (vs) ibrutinib in previously treated chronic...

Active, not recruiting
Chronic Lymphocytic Leukemia
Drug: Ibrutinib
Drug: Acalabrutinib

Phase 3

Acerta Pharma
Acerta Pharma

Columbus, Ohio, United States and 130 other locations

This is a Phase 1/2, open-label, multicenter study to determine the efficacy and safety of JCAR017 in adult subjects with relapsed or refractory CLL...

Enrolling
Lymphoma, Small Lymphocytic
Leukemia, Lymphocytic, Chronic, B-Cell
Biological: JCAR017 (lisocabtagene maraleucel) + venetoclax
Biological: JCAR017 (lisocabtagene maraleucel) + ibrutinib

Phase 1, Phase 2

Juno Therapeutics

Columbus, Ohio, United States and 69 other locations

The purpose of this study is to compare the efficacy and safety of pirtobruitinib (LOXO-305) to ibrutinib in participants with CLL/SLL. Participants...

Enrolling
Leukemia, B-cell
Small Lymphocytic Lymphoma
Drug: Pirtobrutinib
Drug: Ibrutinib

Phase 3

Loxo Oncology
Loxo Oncology

Columbus, Ohio, United States and 179 other locations

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