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Find clinical trials for Chronic Lymphocytic Leukemia in Columbus, OH

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Related conditions:

B-Cell Chronic Lymphocytic Leukemia
Lymphoma
Non-Hodgkin Lymphoma
Leukemia
Mantle-Cell Lymphoma
Diffuse Large B-Cell Lymphoma
B-Cell Lymphoma

Chronic Lymphocytic Leukemia trials near Columbus, OH, USA:

A Study of Emavusertib + An Approved Bruton Tyrosine Kinase Inhibitor (BTKi) in Participants With Chronic Lymphocytic Leukemia (CLL) and Other B-cell Malignancies

The primary objective of the study for Cohort 1 and Cohort 2 is to assess the anticancer activity of emavusertib in combination with zanubrutinib in...

Enrolling
Chronic Lymphocytic Leukemia
B-cell Malignancies
Drug: Emavusertib
Drug: Zanubrutinib

Phase 2

Curis

Columbus, Ohio, United States and 10 other locations

This phase II trial tests how well nemtabrutinib and venetoclax work in treating patients with chronic lymphocytic leukemia...

Begins enrollment in 1 month
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Other: Questionnaire Administration
Drug: Nemtabrutinib

Phase 2

Jennifer Woyach

Columbus, Ohio, United States

and preliminary efficacy of ZE50-0134 in relapsed and refractory chronic lymphocytic leukemia, small lymphocytic ...

Enrolling
CLL (Chronic Lymphocytic Leukemia)
SLL (Small Lymphocytic Lymphoma)
Drug: ZE 50-0134

Phase 1

Lomond Therapeutics Holdings, Inc.

Columbus, Ohio, United States and 3 other locations

Chronic lymphocytic leukemia (CLL) is the most common leukemia (cancer of blood cells). The purpose of this study...

Enrolling
Chronic Lymphocytic Leukemia (CLL)
Drug: Venetoclax
Drug: Obinutuzumab

Phase 2

AbbVie
AbbVie

Columbus, Ohio, United States and 57 other locations

This study is evaluating the safety and efficacy of the combined use of acalabrutinib and ACP-319, for the treatment of chronic lymphocytic...

Active, not recruiting
Chronic Lymphocytic Leukemia
Drug: ACP-319
Drug: acalabrutinib

Phase 1

Acerta Pharma
Acerta Pharma

Columbus, Ohio, United States and 2 other locations

The main goal of this study is to show that people with certain immune problems (from Chronic Lymphocytic Leukemia, Multip...

Enrolling
Chronic Lymphocytic Leukemia, Multiple Myeloma, or Non-Hodgkin Lymphoma
Drug: Gamunex-C, 10% Injectable Solution

Phase 3

Grifols
Grifols

Columbus, Ohio, United States and 4 other locations

This study is evaluating the safety and efficacy of a new BTK inhibitor, acalabrutinib, for the treatment of chronic lymphocytic le...

Active, not recruiting
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: Acalabrutinib

Phase 1, Phase 2

Acerta Pharma
Acerta Pharma

Columbus, Ohio, United States and 11 other locations

Study J2N-MC-JZ01 (JZ01) is an individual-study appendix (ISA) under master protocol J2N-MC-JZNY, and represents participants from the completed orig...

Enrolling
Chronic Lymphocytic Leukemia
Non-Hodgkin Lymphoma
Drug: Pirtobrutinib

Phase 4

Lilly
Lilly

Columbus, Ohio, United States and 34 other locations

monotherapy in participants with relapsed or refractory (R/R) chronic lymphocytic leukemia (CLL) or small lymphocytic...

Enrolling
Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Drug: Rituximab
Drug: Tocilizumab

Phase 1

Roche
Roche

Columbus, Ohio, United States and 31 other locations

This study is designed to evaluate progression-free survival (PFS) endpoint for acalabrutinib versus (vs) ibrutinib in previously treated chronic...

Active, not recruiting
Chronic Lymphocytic Leukemia
Drug: Ibrutinib
Drug: Acalabrutinib

Phase 3

Acerta Pharma
Acerta Pharma

Columbus, Ohio, United States and 129 other locations

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