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Find clinical trials for Chronic Lymphocytic Leukemia in Columbus, OH

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Related conditions:

B-Cell Chronic Lymphocytic Leukemia
Lymphoma
Leukemia
Non-Hodgkin Lymphoma
Mantle-Cell Lymphoma
Diffuse Large B-Cell Lymphoma
B-Cell Lymphoma

Chronic Lymphocytic Leukemia trials near Columbus, OH, USA:

A Study of Emavusertib + An Approved Bruton Tyrosine Kinase Inhibitor (BTKi) in Participants With Chronic Lymphocytic Leukemia (CLL) and Other B-cell Malignancies

The primary objective of the study for Cohort 1 and Cohort 2 is to assess the anticancer activity of emavusertib in combination with zanubrutinib in...

Enrolling
Chronic Lymphocytic Leukemia
B-cell Malignancies
Drug: Emavusertib
Drug: Zanubrutinib

Phase 2

Curis

Columbus, Ohio, United States and 2 other locations

This phase II trial tests how well nemtabrutinib and venetoclax work in treating patients with chronic lymphocytic leukemia...

Not yet enrolling
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Other: Questionnaire Administration
Drug: Nemtabrutinib

Phase 2

Jennifer Woyach

Columbus, Ohio, United States

and preliminary efficacy of ZE50-0134 in relapsed and refractory chronic lymphocytic leukemia, small lymphocytic ...

Enrolling
CLL (Chronic Lymphocytic Leukemia)
SLL (Small Lymphocytic Lymphoma)
Drug: ZE 50-0134

Phase 1

Lomond Therapeutics Holdings, Inc.

Columbus, Ohio, United States and 3 other locations

This study is evaluating the safety and efficacy of the combined use of acalabrutinib and ACP-319, for the treatment of chronic lymphocytic...

Active, not recruiting
Chronic Lymphocytic Leukemia
Drug: ACP-319
Drug: acalabrutinib

Phase 1

Acerta Pharma
Acerta Pharma

Columbus, Ohio, United States and 2 other locations

Chronic lymphocytic leukemia (CLL) is the most common leukemia (cancer of blood cells). The purpose of this study...

Enrolling
Chronic Lymphocytic Leukemia (CLL)
Drug: Venetoclax
Drug: Obinutuzumab

Phase 2

AbbVie
AbbVie

Columbus, Ohio, United States and 57 other locations

This study is evaluating the safety and efficacy of a new BTK inhibitor, acalabrutinib, for the treatment of chronic lymphocytic le...

Active, not recruiting
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: Acalabrutinib

Phase 1, Phase 2

Acerta Pharma
Acerta Pharma

Columbus, Ohio, United States and 11 other locations

Study J2N-MC-JZ01 (JZ01) is an individual-study appendix (ISA) under master protocol J2N-MC-JZNY, and represents participants from the completed orig...

Enrolling
Chronic Lymphocytic Leukemia
Non-Hodgkin Lymphoma
Drug: Pirtobrutinib

Phase 4

Lilly
Lilly

Columbus, Ohio, United States and 34 other locations

monotherapy in participants with relapsed or refractory (R/R) chronic lymphocytic leukemia (CLL). This study will also all...

Enrolling
Chronic Lymphocytic Leukemia
Drug: Tocilizumab
Drug: Venetoclax

Phase 1

Roche
Roche

Columbus, Ohio, United States and 31 other locations

This study is designed to evaluate progression-free survival (PFS) endpoint for acalabrutinib versus (vs) ibrutinib in previously treated chronic...

Active, not recruiting
Chronic Lymphocytic Leukemia
Drug: Ibrutinib
Drug: Acalabrutinib

Phase 3

Acerta Pharma
Acerta Pharma

Columbus, Ohio, United States and 129 other locations

objective of this study is to compare the efficacy of sonrotoclax plus zanubrutinib versus venetoclax plus obinutuzumab in participants with chronic...

Active, not recruiting
CLL
Drug: Zanubrutinib
Drug: Sonrotoclax

Phase 3

BeOne Medicines

Columbus, Ohio, United States and 203 other locations

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