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Find clinical trials for Chronic Lymphocytic Leukemia in Miami, FL

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Related conditions:

B-Cell Chronic Lymphocytic Leukemia
Lymphoma
Leukemia
Non-Hodgkin Lymphoma
Lymphoid Leukemia
Mantle-Cell Lymphoma
Diffuse Large B-Cell Lymphoma

Chronic Lymphocytic Leukemia trials near Miami, FL, USA:

A Phase II Study of Ibrutinib Plus FCR in Previously Untreated, Younger Patients With Chronic Lymphocytic Leukemia (iFCR)

new drug called ibrutinib in combination with the standard drugs fludarabine, cyclophosphamide, and rituximab (FCR) as a possible treatment for Chronic...

Active, not recruiting
Chronic Lymphocytic Leukemia
Leukemia
Drug: Rituximab
Drug: Cyclophosphamide

Phase 2

Dana-Farber Cancer Institute
Dana-Farber Cancer Institute

Miami, Florida, United States and 8 other locations

The primary objective of the study for Cohort 1 and Cohort 2 is to assess the anticancer activity of emavusertib in combination with zanubrutinib in...

Enrolling
Chronic Lymphocytic Leukemia
B-cell Malignancies
Drug: Emavusertib
Drug: Zanubrutinib

Phase 2

Curis

Miami Beach, Florida, United States

zanubrutinib treatment in participants with previously untreated chronic lymphocytic leukemia (CLL). This study is designe...

Active, not recruiting
Chronic Lymphocytic Leukemia
Drug: Sonrotoclax
Drug: Zanubrutinib

Phase 2

BeOne Medicines

Weston, Florida, United States and 33 other locations

Study J2N-MC-JZ01 (JZ01) is an individual-study appendix (ISA) under master protocol J2N-MC-JZNY, and represents participants from the completed orig...

Enrolling
Chronic Lymphocytic Leukemia
Non-Hodgkin Lymphoma
Drug: Pirtobrutinib

Phase 4

Lilly
Lilly

Miami, Florida, United States and 34 other locations

or venetoclax plus rituximab retreatment) in participants with chronic lymphocytic leukemia (CLL) or small lymphocytic...

Enrolling
Chronic Lymphocytic Leukemia
CLL
Drug: Bendamustine
Drug: Rituximab

Phase 3

BeOne Medicines

Weston, Florida, United States and 104 other locations

The purpose of this study is to evaluate the efficacy and safety of ibrutinib + venetoclax (I+V) and ibrutinib monotherapy regimens in which dosing o...

Enrolling
Small Lymphocytic Lymphoma
Leukemia, Lymphocytic, Chronic, B-Cell
Drug: Venetoclax
Drug: Ibrutinib

Phase 2

Janssen (J&J Innovative Medicine)
Janssen (J&J Innovative Medicine)

Miami Beach, Florida, United States and 73 other locations

objective of this study is to compare the efficacy of sonrotoclax plus zanubrutinib versus venetoclax plus obinutuzumab in participants with chronic...

Active, not recruiting
CLL
Drug: Zanubrutinib
Drug: Sonrotoclax

Phase 3

BeOne Medicines

Miami Beach, Florida, United States and 204 other locations

The purpose of this study is to compare the efficacy and safety of pirtobrutinib (LOXO-305; Arm A) compared to BR (Arm B) in patients with CLL/SLL wh...

Active, not recruiting
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: Pirtobrutinib
Drug: Bendamustine

Phase 3

Loxo Oncology
Loxo Oncology

Coral Springs, Florida, United States and 107 other locations

This research study is assessing a new drug, duvelisib, in combination with a drug that is already FDA approved, venetoclax, as a possible treatment...

Active, not recruiting
Chronic Lymphocytic Leukemia
Richter Syndrome
Drug: Venetoclax
Drug: Duvelisib

Phase 1, Phase 2

Dana-Farber Cancer Institute
Dana-Farber Cancer Institute

Miami, Florida, United States and 6 other locations

The main purpose of Part 1 of this study is to assess the efficacy and safety of 3 dose levels of Pirtobrutinib in participants with chronic ...

Enrolling
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: Pirtobrutinib

Phase 2

Loxo Oncology
Loxo Oncology

Miami, Florida, United States and 133 other locations

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