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Find clinical trials for Chronic Lymphocytic Leukemia in Pittsburgh, PA

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Related conditions:

B-Cell Chronic Lymphocytic Leukemia
Leukemia
Lymphoid Leukemia
Lymphoma
B-Cell Lymphoma
Mantle-Cell Lymphoma
Non-Hodgkin Lymphoma

Chronic Lymphocytic Leukemia trials near Pittsburgh, PA, USA:

Study Evaluating Safety and Efficacy of JCAR017 in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL)

This is a Phase 1/2, open-label, multicenter study to determine the efficacy and safety of JCAR017 in adult subjects with relapsed or refractory CLL...

Enrolling
Lymphoma, Small Lymphocytic
Leukemia, Lymphocytic, Chronic, B-Cell
Biological: JCAR017 (lisocabtagene maraleucel) + venetoclax
Biological: JCAR017 (lisocabtagene maraleucel) + ibrutinib

Phase 1, Phase 2

Juno Therapeutics

Pittsburgh, Pennsylvania, United States and 69 other locations

participants with hypogammaglobulinemia (HGG) associated with B-cell chronic lymphocytic leukemia (CLL) in comparison to t...

Enrolling
B-cell Chronic Lymphocytic Leukemia
Hypogammaglobulinemia
Drug: Xembify
Drug: Placebo

Phase 3

Grifols
Grifols

Pittsburgh, Pennsylvania, United States and 27 other locations

ALLO-501A in adults with relapsed or refractory large B-cell lymphoma and assess the safety of ALLO-501A in adults with relapsed or refractory chronic...

Enrolling
Relapsed or Refractory Large B Cell Lymphoma, Relapsed or Refractory Chronic Lymphocytic Leukemia, Relapsed or Refractory Small Lymphocytic Lymphoma
Drug: Fludarabine
Biological: ALLO-647

Phase 1, Phase 2

Allogene Therapeutics

Pittsburgh, Pennsylvania, United States and 38 other locations

This is a Phase 1/2, study evaluating IOV-2001 (Adoptive Cell Therapy) composed of autologous PBL (Peripheral Blood Lymphocytes) in patients...

Active, not recruiting
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: High dose IL-2
Biological: IOV-2001

Phase 1, Phase 2

Iovance Biotherapeutics

Pittsburgh, Pennsylvania, United States and 3 other locations

The purpose of this study is to evaluate the efficacy and safety of acalabrutinib in combination with venetoclax and acalabrutinib in combination wit...

Active, not recruiting
Chronic Lymphocytic Leukemia
Drug: Venetoclax
Drug: Obinutuzumab

Phase 3

Acerta Pharma
Acerta Pharma

Pittsburgh, Pennsylvania, United States and 170 other locations

this approach to reliably generate product and to safely administer the product to patients who have B-Cell Lymphoma and B-Acute Lymphoblastic Leukemia...

Enrolling
B Acute Lymphoblastic Leukemia
Chronic Lymphocytic Leukemia
Drug: Chimeric Antigen Receptor (CAR) T-Cell Product (Autologous)

Phase 2

John Lister

Pittsburgh, Pennsylvania, United States

\[DLBCL\], adult T-cell leukemia-lymphoma \[ATL\], and indolent non Hodgkin lymphomas such as follicular lymphoma \[FL\] and chronic...

Enrolling
Hematological Malignancies
Drug: KPG-818

Phase 1

Kangpu Biopharmaceuticals

Pittsburgh, Pennsylvania, United States and 9 other locations

The purpose of this trial is to measure the following in participants with relapsed and/or refractory B-cell lymphoma who receive epcoritamab, an ant...

Active, not recruiting
Small Lymphocytic Lymphoma (SLL)
MCL
Biological: Epcoritamab

Phase 1, Phase 2

Genmab
Genmab

Pittsburgh, Pennsylvania, United States and 84 other locations

GSK-3β is a potentially important therapeutic target in human malignancies. The Actuate 1801 Phase 1/2 study is designed to evaluate the safety and e...

Active, not recruiting
Acute T Cell Leukemia Lymphoma
Neoplasm of Lung
Drug: Gemcitabine - 21 day cycle
Drug: Lomustine

Phase 2

Actuate Therapeutics

Pittsburgh, Pennsylvania, United States and 65 other locations

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