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A study of acalabrutinib plus venetoclax (AV) versus venetoclax plus obinutuzumab (VO) in previously untreated chronic lymphocytic ...
Phase 3
Salt Lake City, Utah, United States and 40 other locations
This study is evaluating the safety and efficacy of a new BTK inhibitor, acalabrutinib, for the treatment of chronic lymphocytic le...
Phase 1, Phase 2
Salt Lake City, Utah, United States and 11 other locations
This is an open-label, multicenter, phase Ib/II study of the combination of RP-3500 and olaparib in R/R CLL patients with DDR deficiencies.
Phase 1, Phase 2
Salt Lake City, Utah, United States
This phase I trial studies the side effects and best dose of selinexor when given together with ibrutinib in treating patients with chronic ...
Phase 1
Salt Lake City, Utah, United States and 1 other location
The purpose of this study is to evaluate the efficacy and safety of ibrutinib + venetoclax (I+V) and ibrutinib monotherapy regimens in which dosing o...
Phase 2
Ogden, Utah, United States of America and 21 other locations
This is a Phase 1/2, open-label, multicenter study to determine the efficacy and safety of JCAR017 in adult subjects with relapsed or refractory CLL...
Phase 1, Phase 2
Salt Lake City, Utah, United States and 68 other locations
This study will evaluate the efficacy and safety of venetoclax and obinutuzumab (VEN + G) compared with fludarabine + cyclophosphamide + rituximab or...
Phase 3
Ogden, Utah, United States of America and 47 other locations
A Phase I/II Dose-Escalation and Expansion Study Of The Selective PKC-Β Inhibitor MS-553 In Patients With Chronic Lymphocytic Leukemia...
Phase 1, Phase 2
Salt Lake City, Utah, United States and 4 other locations
This is an open-label, multi-center Phase 1/2 study of oral LOXO-305 (pirtobrutinib) in patients with CLL/SLL and NHL who have failed or are intolera...
Phase 1, Phase 2
Salt Lake City, Utah, United States and 55 other locations
with obinutuzumab (Arm B) for the treatment of previously untreated chronic lymphocytic leukemia (CLL). Secondary objectiv...
Phase 3
Salt Lake City, Utah, United States and 154 other locations
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