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Find clinical trials for Chronic Lymphocytic Leukemia in St Louis, MO

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Related conditions:

B-Cell Chronic Lymphocytic Leukemia
Leukemia
Lymphoid Leukemia
Lymphoma
B-Cell Lymphoma
Mantle-Cell Lymphoma
Non-Hodgkin Lymphoma

Chronic Lymphocytic Leukemia trials near St Louis, MO, USA:

A Study of Acalabrutinib Plus Venetoclax Versus Venetoclax Plus Obinutuzumab in Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (MAJIC)

A study of acalabrutinib plus venetoclax (AV) versus venetoclax plus obinutuzumab (VO) in previously untreated chronic lymphocytic ...

Active, not recruiting
Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Drug: Obinutuzumab
Drug: Venetoclax

Phase 3

AstraZeneca
AstraZeneca

Saint Louis, Missouri, United States and 40 other locations

This is a Phase 1/2 dose-escalation study of BTCT4465A (Mosunetuzumab) administered as a single agent and in combination with atezolizumab in partici...

Active, not recruiting
Lymphocytic Leukemia, Chronic
Lymphoma, Non Hodgkin
Drug: BTCT4465A (Mosunetuzumab) IV
Drug: BTCT4465A (Mosunetuzumab) SC

Phase 1, Phase 2

Genentech
Genentech

Saint Louis, Missouri, United States and 48 other locations

To compare efficacy between zanubrutinib versus bendamustine and rituximab in patients with previously untreated CLL/SLL, as measured by progression...

Active, not recruiting
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: Rituximab
Drug: Venetoclax

Phase 3

BeiGene
BeiGene

Saint Louis, Missouri, United States and 178 other locations

This study is a first-in-human, Phase 1a/1b, multicenter, open-label study to determine the safety, tolerability, and pharmacokinetics of aplitabart...

Enrolling
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: Bevacizumab (and approved biosimilars)
Drug: FOLFIRI

Phase 1

IGM Biosciences

Saint Louis, Missouri, United States and 57 other locations

The purpose of this study is to collect long-term safety and efficacy data for participants treated with ibrutinib and to provide ongoing access to i...

Invitation-only
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: Ibrutinib

Phase 3

Janssen (J&J Innovative Medicine)

Saint Louis, Missouri, United States and 173 other locations

This is an open-label, multicenter, Phase 1/2 study evaluating the safety and efficacy of CTX112™ in subjects with relapsed or refractory B-cell mali...

Enrolling
Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
Marginal Zone Lymphoma
Biological: CTX112

Phase 1, Phase 2

CRISPR Therapeutics

Saint Louis, Missouri, United States and 1 other location

This research study is evaluating the combination of two drugs, copanlisib and venetoclax, as a possible treatment for trelapsed/refractory diffuse l...

Active, not recruiting
Relapsed Diffuse Large B-Cell Lymphoma
Diffuse Large B Cell Lymphoma
Drug: Copanlisib
Drug: Venetoclax

Phase 1, Phase 2

Dana-Farber Cancer Institute
Dana-Farber Cancer Institute

Saint Louis, Missouri, United States and 2 other locations

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