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Find clinical trials for Chronic Lymphocytic Leukemia in Valencia, VC

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Related conditions:

B-Cell Chronic Lymphocytic Leukemia
Leukemia
Lymphoid Leukemia
Lymphoma
B-Cell Lymphoma
Non-Hodgkin Lymphoma
Mantle-Cell Lymphoma

Chronic Lymphocytic Leukemia trials near Valencia, VC, ESP:

A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010)

of nemtabrutinib plus venetoclax is superior to VR with respect to progression-free survival (PFS) per 2018 International Workshop on Chronic...

Enrolling
Lymphoma, Small Lymphocytic
Leukemia, Chronic Lymphocytic
Drug: Nemtabrutinib
Biological: Rituximab

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Valencia, Valenciana, Comunitat, Spain and 47 other locations

) and prednisone).The study includes patients with relapsed/refractory chronic lymphocytic leukemia (R/R CLL)/small lymphocytic...

Enrolling
Small Lymphocytic Lymphoma
Relapsed/Refractory Chronic Lymphocytic Leukemia
Drug: Lenalidomide
Drug: Venetoclax

Phase 1, Phase 2

Genmab
Genmab

Valencia, València, Spain and 75 other locations

Status recently updated

The purpose of this study is to compare the efficacy and safety of fixed duration pirtobruitinib (LOXO-305) with VR (Arm A) compared to VR alone (Arm...

Enrolling
Active, not recruiting
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: Venetoclax
Drug: Rituximab

Phase 3

Loxo Oncology
Loxo Oncology

Valencia, Spain and 216 other locations

The purpose of this study is to evaluate the efficacy and safety of acalabrutinib in combination with venetoclax and acalabrutinib in combination wit...

Active, not recruiting
Chronic Lymphocytic Leukemia
Drug: Venetoclax
Drug: Obinutuzumab

Phase 3

Acerta Pharma
Acerta Pharma

Valencia, Spain and 170 other locations

To compare efficacy between zanubrutinib versus bendamustine and rituximab in patients with previously untreated CLL/SLL, as measured by progression...

Active, not recruiting
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: Rituximab
Drug: Venetoclax

Phase 3

BeiGene
BeiGene

Valencia, Spain and 178 other locations

A Phase 1 first-in-human dose-escalation and dose-expansion study of BMF-219, an oral covalent menin inhibitor, in adult patients with AML, ALL (with...

Enrolling
Acute Mixed-Phenotype Leukemia
Small Lymphocytic Lymphoma
Drug: BMF-219

Phase 1

Biomea Fusion

Valencia, Spain and 40 other locations

venetoclax versus obinutuzumab + chlorambucil in participants with chronic lymphocytic leukemia (CLL) and coexisting medic...

Active, not recruiting
Lymphocytic Leukemia, Chronic
Drug: Chlorambucil
Drug: Venetoclax

Phase 3

Roche
Roche

Valencia, Spain and 136 other locations

the efficacy of acalabrutinib compared with rituximab in combination with idelalisib or bendamustine in previously treated subjects with chronic...

Active, not recruiting
Chronic Lymphocytic Leukemia
Drug: Rituximab
Drug: Idelalisib

Phase 3

Acerta Pharma
Acerta Pharma

Valencia, Spain and 156 other locations

autoleucel will be investigated in combination with ibrutinib in chronic lymphocytic leukemia (CLL)/small lymphocytic...

Enrolling
Small Lymphocytic Lymphoma
Acute Lymphoblastic Leukemia
Drug: Ibrutinib
Biological: Rapcabtagene autoleucel single agent

Phase 1, Phase 2

Novartis
Novartis

Valencia, Comunidad Valenciana, Spain and 42 other locations

GSK-3β is a potentially important therapeutic target in human malignancies. The Actuate 1801 Phase 1/2 study is designed to evaluate the safety and e...

Active, not recruiting
Acute T Cell Leukemia Lymphoma
Neoplasm of Lung
Drug: Gemcitabine - 21 day cycle
Drug: 9-ING-41

Phase 2

Actuate Therapeutics

Valencia, Spain and 65 other locations

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