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Find clinical trials for Colon Cancer in Cleveland, OH

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Related conditions:

Colonic Cancer
Colorectal Cancer
Rectal Cancer
Non-Small-Cell Lung Carcinoma
Pancreatic Cancer
Cancer
Neoplasm Metastasis

Colon Cancer trials near Cleveland, OH, USA:

Neoadjuvant Pembrolizumab and Porustobart in Resectable pMMR/MSS Colon Cancer

and pembrolizumab, before surgery can treat a common type of colon cancer called microsatellite stable (MSS) colon cancer...

Begins enrollment this month
Proficient Mismatch Repair (pMMR) Colon Cancer
Microsatellite Stable (MSS) Colon Cancer
Drug: Porustobart
Drug: Pembrolizumab

Phase 2

Solstice Oncology, Inc.

Cleveland, Ohio, United States and 29 other locations

(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...

Enrolling
Colonic Neoplasms
Neoplasms, Colon
Drug: CAPEOX
Biological: Dostarlimab

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Cleveland, Ohio, United States and 262 other locations

to participants with advanced solid tumors, including rearranged during transfection (RET)-fusion-positive solid tumors, medullary thyroid cancer...

Active, not recruiting
Colon Cancer
Medullary Thyroid Cancer
Drug: LOXO-292

Phase 1, Phase 2

Lilly
Lilly

Cleveland, Ohio, United States and 85 other locations

the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor DNA (ctDNA) after surgery for colon...

Enrolling
Stage III Colon Cancer
Drug: mFOLFOX6 3-6 month
Device: Signatera test

Phase 2, Phase 3

NRG Oncology
NRG Oncology

Cleveland, Ohio, United States and 1076 other locations

This is a study to evaluate the safety and potential anti-tumor activity of an investigational agent called ARV-806 in Adults with Advanced Cancer...

Active, not recruiting
Advanced Solid Cancer
KRAS G12D Mutation
Drug: ARV-806

Phase 1, Phase 2

Arvinas
Arvinas

Cleveland, Ohio, United States and 13 other locations

The main purpose of the study is to assess whether the study drug, LY4066434, is safe and tolerable when administered to participants with locally ad...

Active, not recruiting
Non-small Cell Lung Cancer
Colorectal Cancer
Drug: Pembrolizumab
Drug: Irinotecan

Phase 1

Lilly
Lilly

Cleveland, Ohio, United States and 46 other locations

chemotherapy and bevacizumab with or without INCA33890 in the first-line treatment of metastatic microsatellite stable colorectal cancer....

Enrolling
CRC (Colorectal Cancer)
Drug: INCA33890
Drug: Placebo

Phase 3

Incyte
Incyte

Cleveland, Ohio, United States and 282 other locations

in very high numbers).This includes (but limited to) the following cancer types:Non-Small Cell Lung Cancer (NSCLC): It's a type of ...

Active, not recruiting
Carcinoma, Pancreatic Ductal
Carcinoma, Non-Small-Cell Lung
Combination Product: pemetrexed
Combination Product: Oxaliplatin

Phase 1

Pfizer
Pfizer

Cleveland, Ohio, United States and 26 other locations

The purpose of this study is to learn more about a new medicine called PF-08634404, and how well it works in people with cancer of the colon...

Enrolling
Colonic Diseases
Intestinal Neoplasms
Biological: Bevacizumab
Drug: Chemotherapy

Phase 3

Pfizer
Pfizer

Cleveland, Ohio, United States and 307 other locations

with standard chemotherapy for the potential treatment of colorectal cancer that:* has spread to other parts of the body (metastatic);* has ...

Active, not recruiting
Neoplasms
Drug: Cetuximab
Drug: Oxaliplatin

Phase 3

Pfizer
Pfizer

Cleveland, Ohio, United States and 274 other locations

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