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Find clinical trials for Colon Cancer in Columbus, OH

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Related conditions:

Colorectal Cancer
Colonic Cancer
Cancer
Adenocarcinoma
Neoplasm Metastasis
Non-Small-Cell Lung Carcinoma
Carcinoma

Colon Cancer trials near Columbus, OH, USA:

A Study of Selpercatinib (LOXO-292) in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001)

This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor ...

Active, not recruiting
Any Solid Tumor
Colon Cancer
Drug: LOXO-292

Phase 1, Phase 2

Lilly
Lilly

Columbus, Ohio, United States and 84 other locations

the efficacy of CTX-009 in patients with metastatic colorectal cancer.A Simon Two-Stage adaptive design will enroll approximately 37 patient...

Active, not recruiting
Metastatic Colorectal Cancer
Colon Cancer
Drug: CTX-009

Phase 2

Compass Therapeutics

Columbus, Ohio, United States of America and 6 other locations

Phase 1 open label sequential dose escalation and cohort expansion study evaluating the safety, tolerability and preliminary antitumor activity of CO...

Active, not recruiting
Advanced Cancer
Colon Cancer
Drug: Cohort expansion: COM902 (RDFE) monotherapy.
Combination Product: Cohort expansion: Triplet combination of COM902 + COM701 + Pembrolizumab.

Phase 1

Compugen

Columbus, Ohio, United States and 8 other locations

This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor...

Enrolling
Stage III Colon Cancer
Drug: mFOLFOX6 3-6 month
Device: Signatera test

Phase 2, Phase 3

NRG Oncology
NRG Oncology

Columbus, Ohio, United States and 944 other locations

Exon 14 skipping mutations, NSCLC harboring MET amplification, solid tumors harboring MET amplification, solid tumors harboring MET...

Enrolling
Brain Tumor
Colon Cancer
Drug: APL-101 Oral Capsules

Phase 2

Apollomics

Columbus, Ohio, United States and 90 other locations

with standard chemotherapy for the potential treatment of colorectal cancer that:* has spread to other parts of the body (metastatic);* has ...

Active, not recruiting
Neoplasms
Drug: Cetuximab
Drug: Oxaliplatin

Phase 3

Pfizer
Pfizer

Columbus, Ohio, United States and 274 other locations

evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with advanced solid tumors...

Enrolling
Metastatic Cancer
Advanced Cancer
Drug: Cetuximab
Drug: Afatinib

Phase 1, Phase 2

Mirati Therapeutics
Mirati Therapeutics

Columbus, Ohio, United States and 233 other locations

in each subject population expansion cohort of advanced solid tumors that harbor a ROS1, NTRK1, NTRK2, or NTRK3 gene rearrangement. The seco...

Enrolling
Locally Advanced Solid Tumors
Metastatic Solid Tumors
Drug: Oral repotrectinib (TPX-0005)

Phase 1, Phase 2

Turning Point Therapeutics
Turning Point Therapeutics

Columbus, Ohio, United States and 161 other locations

a three-year event rate of adenomas and second primary colorectal cancers in patients previously treated for Stages 0 through III colon...

Active, not recruiting
Colorectal Neoplasms
Drug: Eflornithine placebo & sulindac placebo
Drug: Eflornithine plus sulindac

Phase 3

SWOG Cancer Research Network
SWOG Cancer Research Network

Columbus, Ohio, United States and 989 other locations

Patients with Familial Adenomatous Polyposis (FAP) who are undergoing endoscopic surveillance will be given Encapsulated Rapamycin (eRapa) at one of...

Active, not recruiting
Familial Adenomatous Polyposis
Drug: Encapsulated Rapamycin (eRapa)

Phase 2

Rapamycin Holdings Inc.

Columbus, Ohio, United States and 3 other locations

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