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Find clinical trials for Colon Cancer in Columbus, OH

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Related conditions:

Colorectal Cancer
Colonic Cancer
Cancer
Neoplasm Metastasis
Adenocarcinoma
Lung Cancer
Non-Small-Cell Lung Carcinoma

Colon Cancer trials near Columbus, OH, USA:

A Study of CTX-009 in Adult Patients With Metastatic Colorectal Cancer (COMPANION-003)

the efficacy of CTX-009 in patients with metastatic colorectal cancer.A Simon Two-Stage adaptive design will enroll approximately 37 patient...

Active, not recruiting
Metastatic Colorectal Cancer
Colon Cancer
Drug: CTX-009

Phase 2

Compass Therapeutics

Columbus, Ohio, United States and 6 other locations

to participants with advanced solid tumors, including rearranged during transfection (RET)-fusion-positive solid tumors, medullary thyroid cancer...

Enrolling
Colon Cancer
Medullary Thyroid Cancer
Drug: LOXO-292

Phase 1, Phase 2

Loxo Oncology
Loxo Oncology

Columbus, Ohio, United States and 83 other locations

the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor DNA (ctDNA) after surgery for colon...

Enrolling
Stage III Colon Cancer
Drug: mFOLFOX6 3-6 month
Device: Signatera test

Phase 2, Phase 3

NRG Oncology

Columbus, Ohio, United States and 831 other locations

Phase 1 open label sequential dose escalation and cohort expansion study evaluating the safety, tolerability and preliminary antitumor activity of CO...

Enrolling
Advanced Cancer
Colon Cancer
Drug: Cohort expansion: COM902 (RDFE) monotherapy.
Drug: Cohort expansion: COM902 in combination with COM701 (both at the RDFE).

Phase 1

Compugen

Columbus, Ohio, United States and 8 other locations

Locations recently updated

This study will evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with adva...

Enrolling
Metastatic Cancer
Advanced Cancer
Drug: Cetuximab
Drug: Afatinib

Phase 1, Phase 2

Mirati Therapeutics
Mirati Therapeutics

Columbus, Ohio, United States and 112 other locations

The purpose of this study is to further evaluate the efficacy and safety of niraparib in patients with locally advanced or metastatic solid tumors an...

Active, not recruiting
Esophageal Cancer
Urologic Cancer
Drug: Niraparib

Phase 2

Tempus AI
Tempus AI

Columbus, Ohio, United States and 79 other locations

To assess:* efficacy of APL-101 as monotherapy for the treatment of NSCLC harboring MET Exon 14 skipping mutations, NSCLC harboring MET amplification...

Enrolling
Colon Cancer
Lung Cancer
Drug: APL-101 Oral Capsules

Phase 2

Apollomics

Columbus, Ohio, United States and 90 other locations

with standard chemotherapy for the potential treatment of colorectal cancer that:* has spread to other parts of the body (metastatic);* has ...

Enrolling
Neoplasms
Drug: Cetuximab
Drug: Oxaliplatin

Phase 3

Pfizer
Pfizer

Columbus, Ohio, United States and 409 other locations

a three-year event rate of adenomas and second primary colorectal cancers in patients previously treated for Stages 0 through III colon...

Active, not recruiting
Colorectal Neoplasms
Drug: eflornithine & sulindac placebo
Drug: Eflornithine placebo & sulindac placebo

Phase 3

SWOG Cancer Research Network

Columbus, Ohio, United States and 989 other locations

Colon polyposis (the presence of multiple colon polyps) is very common with Cowden syndrome, as over 60% of patients have 50 or mor...

Active, not recruiting
PTEN Hamartoma Syndrome
PTEN Hamartoma Tumor Syndrome
Drug: Sirolimus

Phase 2

The Ohio State University
The Ohio State University

Columbus, Ohio, United States

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