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(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...
Phase 3
Detroit, Michigan, United States and 262 other locations
Solid tumours are abnormal lumps of tissue that can occur in different parts of the body. The tumours involved in this study have specific genetic ch...
Phase 1, Phase 2
Detroit, Michigan, United States and 21 other locations
to participants with advanced solid tumors, including rearranged during transfection (RET)-fusion-positive solid tumors, medullary thyroid cancer...
Phase 1, Phase 2
Ann Arbor, Michigan, United States and 85 other locations
care (FOLFOX plus bevacizumab) alone and in combination with novel oncology therapies in first-line metastatic microsatellite-stable colorectal cancer...
Phase 1, Phase 2
Ann Arbor, Michigan, United States and 20 other locations
the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor DNA (ctDNA) after surgery for colon...
Phase 2, Phase 3
Detroit, Michigan, United States and 1076 other locations
test whether GSK5460025 alone or in combination (potential combinations may be included in future amendments to the protocol) with other anti-cancer...
Phase 1, Phase 2
Detroit, Michigan, United States and 21 other locations
A Phase 1 dose escalation study in patients with advanced solid tumors harboring KRAS G12C mutation to determine the maximum tolerated dose and recom...
Phase 1
Farmington Hills, Michigan, United States of America and 13 other locations
This study is to evaluate the safety, tolerability, and PK profiles of Elironrasib and Daraxonrasib as monotherapies and combination therapy in patie...
Phase 1, Phase 2
Detroit, Michigan, United States and 54 other locations
chemotherapy and bevacizumab with or without INCA33890 in the first-line treatment of metastatic microsatellite stable colorectal cancer....
Phase 3
Detroit, Michigan, United States and 256 other locations
This is a Phase 1/2 study to assess the safety and efficacy of ELI-002 7P immunotherapy (a lipid-conjugated immune-stimulatory oligonucleotide \[Amph...
Phase 1, Phase 2
Ann Arbor, Michigan, United States and 27 other locations
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