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Find clinical trials for Colon Cancer in London, England

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Related conditions:

Colorectal Cancer
Colonic Cancer
Cancer
Non-Small-Cell Lung Carcinoma
Lung Cancer
Neoplasm Metastasis
Adenocarcinoma

Colon Cancer trials near London, England, GBR:

A Study of Neoadjuvant Dostarlimab Plus Capecitabine Plus Oxaliplatin (CAPEOX) Vs CAPEOX With Previously Untreated T4N0 or Stage III Mismatch Repair Proficient (MMRp)/Microsatellite Stable (MSS) Colon Cancer (AZUR-4)

." . The aim is to see if this new approach can show early signs of effectiveness in treating participants with a specific type of colon cancer...

Not yet enrolling
Neoplasms, Colon
Drug: CAPEOX
Biological: Dostarlimab

Phase 2

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

London, United Kingdom and 14 other locations

(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...

Enrolling
Colonic Neoplasms
Neoplasms, Colon
Drug: CAPEOX
Biological: Dostarlimab

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

London, United Kingdom and 250 other locations

A significant proportion of patients who undergo liver surgery to remove bowel cancer that has spread to the liver (metastases) develop dise...

Active, not recruiting
Colon Cancer
Liver Metastasis
Drug: Icosapent Ethyl
Other: Placebo

Phase 3

Mark A Hull, PhD FRCP

London, United Kingdom and 12 other locations

and pembrolizumab) given together for the treatment of colorectal cancer that:* is metastatic (spread to other parts of the body);* has the ...

Active, not recruiting
Metastatic Colorectal Cancer
Biological: Pembrolizumab
Biological: Cetuximab

Phase 2

Pfizer
Pfizer

London, England, United Kingdom and 111 other locations

This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor ...

Active, not recruiting
Any Solid Tumor
Colon Cancer
Drug: LOXO-292

Phase 1, Phase 2

Loxo Oncology
Loxo Oncology

Sutton, Surrey, United Kingdom and 83 other locations

oral LOXO-292 in pediatric participants with an activating rearranged during transfection (RET) alteration and an advanced solid or primary CNS tumor...

Enrolling
Papillary Thyroid Cancer
Medullary Thyroid Cancer
Drug: LOXO-292

Phase 1, Phase 2

Loxo Oncology
Loxo Oncology

London, Greater London, United Kingdom and 25 other locations

This study will test the safety of a drug called SGN-EGFRd2 in participants with advanced solid tumors. It will also study the side effects ...

Enrolling
Colorectal Neoplasms
Squamous Cell Carcinoma of the Head and Neck
Drug: SGN-EGFRd2

Phase 1

Seagen
Seagen

London, Other, United Kingdom and 12 other locations

This is a first-in-human, open-label, non-randomized, three-part phase 1 trial of INBRX-109, which is a recombinant humanized tetravalent antibody ta...

Enrolling
Colorectal Adenocarcinoma
Ewing Sarcoma
Drug: Pemetrexed
Drug: INBRX-109

Phase 1

Inhibrx Biosciences, Inc

London, United Kingdom and 33 other locations

trial is to determine the safety and efficacy of IP-001 for intratumoral injection administration following thermal ablation of a solid tumor...

Enrolling
Nonsmall Cell Lung Cancer
Colon Cancer
Drug: 1.0% IP-001 for Injection

Phase 1, Phase 2

Immunophotonics

London, United Kingdom and 15 other locations

plus BSC in participants with refractory metastatic colorectal cancer (mCRC). 691 participants were randomized to one of the following treat...

Active, not recruiting
Metastatic Colorectal Cancer
Metastatic Colon Cancer
Drug: Fruquintinib
Drug: Placebo

Phase 3

HUTCHMED
HUTCHMED

London, Middlesex, United Kingdom and 152 other locations

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