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Find clinical trials for Colon Cancer in London, England

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Related conditions:

Colonic Cancer
Colorectal Cancer
Rectal Cancer
Non-Small-Cell Lung Carcinoma
Pancreatic Cancer
Cancer
Neoplasm Metastasis

Colon Cancer trials near London, England, GBR:

Neoadjuvant Pembrolizumab and Porustobart in Resectable pMMR/MSS Colon Cancer

and pembrolizumab, before surgery can treat a common type of colon cancer called microsatellite stable (MSS) colon cancer...

Begins enrollment this month
Proficient Mismatch Repair (pMMR) Colon Cancer
Microsatellite Stable (MSS) Colon Cancer
Drug: Porustobart
Drug: Pembrolizumab

Phase 2

Solstice Oncology, Inc.

London, United Kingdom and 29 other locations

The main goal of this study is to test a new treatment approach for colon cancer. The treatment involves dostarlimab along with a s...

Enrolling
Neoplasms, Colon
Drug: CAPEOX
Biological: Dostarlimab

Phase 2

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

London, United Kingdom and 31 other locations

(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...

Enrolling
Colonic Neoplasms
Neoplasms, Colon
Drug: CAPEOX
Biological: Dostarlimab

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

London, United Kingdom and 262 other locations

A significant proportion of patients who undergo liver surgery to remove bowel cancer that has spread to the liver (metastases) develop dise...

Active, not recruiting
Colon Cancer
Liver Metastasis
Drug: Icosapent Ethyl
Other: Placebo

Phase 3

Mark A Hull, PhD FRCP

London, United Kingdom and 12 other locations

to participants with advanced solid tumors, including rearranged during transfection (RET)-fusion-positive solid tumors, medullary thyroid cancer...

Active, not recruiting
Colon Cancer
Medullary Thyroid Cancer
Drug: LOXO-292

Phase 1, Phase 2

Lilly
Lilly

London, United Kingdom and 85 other locations

The purpose of this study is to assess the safety and tolerability of XmAb®819 administered intravenous (IV) or subcutaneous (SC) in subjects with re...

Enrolling
Clear Cell Renal Cell Carcinoma
Biological: XmAb819

Phase 1

Xencor
Xencor

Cambridge, Cambridgeshire, United Kingdom and 26 other locations

The goal of this clinical trial is to determine the safety and efficacy of IP-001 for intratumoral injection administration following thermal ablatio...

Active, not recruiting
Nonsmall Cell Lung Cancer
Colon Cancer
Drug: 1.0% IP-001 for Injection

Phase 1, Phase 2

Immunophotonics

London, United Kingdom and 15 other locations

This is an open-label, multi-center Phase 1/2 study of oral LOXO-292 in pediatric participants with an activating rearranged during transfection (RET...

Active, not recruiting
Papillary Thyroid Cancer
Medullary Thyroid Cancer
Drug: Selpercatinib

Phase 1, Phase 2

Lilly
Lilly

London, Greater London, United Kingdom and 25 other locations

chemotherapy and bevacizumab with or without INCA33890 in the first-line treatment of metastatic microsatellite stable colorectal cancer....

Enrolling
CRC (Colorectal Cancer)
Drug: INCA33890
Drug: Placebo

Phase 3

Incyte
Incyte

London, United Kingdom and 282 other locations

To assess:* efficacy of APL-101 as monotherapy for the treatment of NSCLC harboring MET Exon 14 skipping mutations, NSCLC harboring MET amplification...

Enrolling
Colon Cancer
Lung Cancer
Drug: APL-101 Oral Capsules

Phase 2

Apollomics

London, United Kingdom and 41 other locations

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