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Find clinical trials for Colon Cancer in Philadelphia, PA

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Related conditions:

Colorectal Cancer
Colonic Cancer
Cancer
Lung Cancer
Neoplasm Metastasis
Non-Small-Cell Lung Carcinoma
Adenocarcinoma

Colon Cancer trials near Philadelphia, PA, USA:

Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer (AZUR-2)

(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...

Enrolling
Colonic Neoplasms
Neoplasms, Colon
Drug: CAPEOX
Biological: Dostarlimab

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Wynnewood, Pennsylvania, United States and 250 other locations

doses of selected chemotherapies will be safe and tolerable for cancer patients with advanced solid tumors. The highest tolerated d...

Active, not recruiting
Breast Cancer
Colon Neoplasms
Drug: Erlotinib
Drug: Temsirolimus

Phase 1

AstraZeneca
AstraZeneca

Philadelphia, Pennsylvania, United States and 3 other locations

The purpose of this study is to examine if Nivolumab by itself, or Nivolumab in combination with other anti-cancer drugs, will result in mea ...

Active, not recruiting
Microsatellite Unstable Colorectal Cancer
Microsatellite Stable Colorectal Cancer
Drug: Ipilimumab
Drug: BMS-986016

Phase 2

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Allentown, Pennsylvania, United States and 31 other locations

This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor ...

Enrolling
Any Solid Tumor
Colon Cancer
Drug: LOXO-292

Phase 1, Phase 2

Loxo Oncology
Loxo Oncology

Philadelphia, Pennsylvania, United States and 83 other locations

RSC-101 is a Phase 1a/1b clinical trial of RSC-1255 in adult study participants with advanced solid tumor malignancies who are intolerant of...

Enrolling
Colon Cancer
Lung Cancer
Drug: RSC-1255 Dose Expansion
Drug: RSC-1255 Dose Escalation

Phase 1

Rascal Therapeutics

Philadelphia, Pennsylvania, United States and 4 other locations

oral LOXO-292 in pediatric participants with an activating rearranged during transfection (RET) alteration and an advanced solid or primary CNS tumor...

Enrolling
Papillary Thyroid Cancer
Medullary Thyroid Cancer
Drug: LOXO-292

Phase 1, Phase 2

Loxo Oncology
Loxo Oncology

Philadelphia, Pennsylvania, United States and 25 other locations

This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor...

Enrolling
Stage III Colon Cancer
Drug: mFOLFOX6 3-6 month
Device: Signatera test

Phase 2, Phase 3

NRG Oncology
NRG Oncology

Philadelphia, Pennsylvania, United States and 878 other locations

This is a first-in-human, open-label, non-randomized, three-part phase 1 trial of INBRX-109, which is a recombinant humanized tetravalent antibody ta...

Enrolling
SDH-deficient Solid Tumors
Solid Tumors
Drug: 5-fluorouracil
Drug: Carboplatin

Phase 1

Inhibrx

Philadelphia, Pennsylvania, United States and 18 other locations

of SNS-101, a novel anti VISTA IgG1 monoclonal antibody as monotherapy or in combination with cemiplimab in patients with advanced solid tumors...

Enrolling
Breast Cancer
Uterine Cancer
Drug: Cemiplimab
Drug: SNS-101 (anti-VISTA)

Phase 1, Phase 2

Sensei Biotherapeutics

Philadelphia, Pennsylvania, United States and 8 other locations

This open-label study will evaluate the safety, tolerability, pharmacokinetics and effect on tumor growth following a single intralesional i...

Active, not recruiting
Metastatic Colorectal Cancer
Metastatic Pancreatic Cancer
Drug: PV-10 (10% rose bengal disodium)

Phase 1

Provectus Biopharmaceuticals

Bethlehem, Pennsylvania, United States and 4 other locations

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