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Find clinical trials for Colon Cancer in Philadelphia, PA

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Related conditions:

Colonic Cancer
Colorectal Cancer
Cancer
Rectal Cancer
Neoplasm Metastasis
Pancreatic Cancer
Non-Small-Cell Lung Carcinoma

Colon Cancer trials near Philadelphia, PA, USA:

The Phoenix Trial: Phase II Trial of Cemiplimab for the Non-operative Management of Localized dMMR Colon Cancer

To learn if cemiplimab can help to control dMMR colon cancer....

Active, not recruiting
Colon Cancer
Drug: Cemiplimab

Phase 2

M.D. Anderson Cancer Center
M.D. Anderson Cancer Center

Camden, New Jersey, United States and 4 other locations

and irinotecan) in participants with metastatic colorectal cancer (mCRC). The main goals of this study are to:* Evaluate the efficacy of the...

Enrolling
Colorectal Cancer (CRC)
Colon Cancer
Drug: FOLFIRI (Irinotecan, 5-Fluorouracil, and Leucovorin)
Drug: fruquintinib

Phase 2

SCRI Development Innovations

Wynnewood, Pennsylvania, United States and 13 other locations

aggressive and challenging to treat. The study will test whether GSK4418959 alone or in combination with a PD-1 inhibitor agent can decrease tumor...

Active, not recruiting
Endometrial Cancer
Solid Tumor
Drug: GSK4418959
Biological: PD-1 inhibitor

Phase 1, Phase 2

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Philadelphia, Pennsylvania, United States and 21 other locations

This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor ...

Active, not recruiting
Any Solid Tumor
Colon Cancer
Drug: LOXO-292

Phase 1, Phase 2

Lilly
Lilly

Philadelphia, Pennsylvania, United States and 85 other locations

oral LOXO-292 in pediatric participants with an activating rearranged during transfection (RET) alteration and an advanced solid or primary CNS tumor...

Active, not recruiting
Papillary Thyroid Cancer
Medullary Thyroid Cancer
Drug: Selpercatinib

Phase 1, Phase 2

Lilly
Lilly

Philadelphia, Pennsylvania, United States and 25 other locations

This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor...

Enrolling
Stage III Colon Cancer
Drug: mFOLFOX6 3-6 month
Device: Signatera test

Phase 2, Phase 3

NRG Oncology
NRG Oncology

Philadelphia, Pennsylvania, United States and 1055 other locations

\[Amph-Peptides 7P\]) as adjuvant treatment in subjects with solid tumors with mutated KRAS/NRAS. This study builds on the experience obtain...

Active, not recruiting
Colorectal Cancer
KRAS G12V
Drug: ELI-002 7P

Phase 1, Phase 2

Elicio Therapeutics
Elicio Therapeutics

Philadelphia, Pennsylvania, United States and 27 other locations

of SNS-101, a novel anti VISTA IgG1 monoclonal antibody as monotherapy or in combination with cemiplimab in patients with advanced solid tumors...

Active, not recruiting
Breast Cancer
Uterine Cancer
Drug: Cemiplimab
Drug: SNS-101 (anti-VISTA)

Phase 1, Phase 2

Sensei Biotherapeutics

Philadelphia, Pennsylvania, United States and 9 other locations

Locations recently updated

chemotherapy and bevacizumab with or without INCA33890 in the first-line treatment of metastatic microsatellite stable colorectal cancer....

Enrolling
CRC (Colorectal Cancer)
Drug: INCA33890
Drug: Placebo

Phase 3

Incyte
Incyte

Philadelphia, Pennsylvania, United States and 275 other locations

evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with advanced solid tumors...

Active, not recruiting
Metastatic Cancer
Advanced Cancer
Drug: Cetuximab
Drug: Afatinib

Phase 1, Phase 2

Mirati Therapeutics
Mirati Therapeutics

Media, Pennsylvania, United States and 231 other locations

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