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Find clinical trials for Colon Cancer in Philadelphia, PA

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Related conditions:

Colonic Cancer
Colorectal Cancer
Rectal Cancer
Non-Small-Cell Lung Carcinoma
Pancreatic Cancer
Cancer
Neoplasm Metastasis

Colon Cancer trials near Philadelphia, PA, USA:

The Phoenix Trial: Phase II Trial of Cemiplimab for the Non-operative Management of Localized dMMR Colon Cancer

To learn if cemiplimab can help to control dMMR colon cancer....

Active, not recruiting
Colon Cancer
Drug: Cemiplimab

Phase 2

M.D. Anderson Cancer Center
M.D. Anderson Cancer Center

Camden, New Jersey, United States and 4 other locations

and irinotecan) in participants with metastatic colorectal cancer (mCRC). The main goals of this study are to:* Evaluate the efficacy of the...

Enrolling
Colorectal Cancer (CRC)
Colon Cancer
Drug: fruquintinib
Drug: FOLFIRI (Irinotecan, 5-Fluorouracil, and Leucovorin)

Phase 2

SCRI Development Innovations

Wynnewood, Pennsylvania, United States and 13 other locations

Solid tumours are abnormal lumps of tissue that can occur in different parts of the body. The tumours involved in this study have specific genetic ch...

Active, not recruiting
Endometrial Cancer
Colon Cancer
Drug: GSK4418959
Biological: PD-1 inhibitor

Phase 1, Phase 2

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Philadelphia, Pennsylvania, United States and 21 other locations

to participants with advanced solid tumors, including rearranged during transfection (RET)-fusion-positive solid tumors, medullary thyroid cancer...

Active, not recruiting
Colon Cancer
Medullary Thyroid Cancer
Drug: LOXO-292

Phase 1, Phase 2

Lilly
Lilly

Philadelphia, Pennsylvania, United States and 85 other locations

the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor DNA (ctDNA) after surgery for colon...

Enrolling
Stage III Colon Cancer
Drug: mFOLFOX6 3-6 month
Device: Signatera test

Phase 2, Phase 3

NRG Oncology
NRG Oncology

Philadelphia, Pennsylvania, United States and 1076 other locations

This is an open-label, multi-center Phase 1/2 study of oral LOXO-292 in pediatric participants with an activating rearranged during transfection (RET...

Active, not recruiting
Papillary Thyroid Cancer
Medullary Thyroid Cancer
Drug: Selpercatinib

Phase 1, Phase 2

Lilly
Lilly

Philadelphia, Pennsylvania, United States and 25 other locations

with either (a) hepatocellular carcinoma (HCC) that is not amenable to resection, transplant or other potentially curative therapy or (b) cancer...

Active, not recruiting
Metastatic Colorectal Cancer
Metastatic Pancreatic Cancer
Drug: PV-10 (10% rose bengal disodium)

Phase 1

Provectus Biopharmaceuticals

Bethlehem, Pennsylvania, United States and 4 other locations

chemotherapy and bevacizumab with or without INCA33890 in the first-line treatment of metastatic microsatellite stable colorectal cancer....

Enrolling
CRC (Colorectal Cancer)
Drug: INCA33890
Drug: Placebo

Phase 3

Incyte
Incyte

Philadelphia, Pennsylvania, United States and 256 other locations

This is a Phase 1/2 study to assess the safety and efficacy of ELI-002 7P immunotherapy (a lipid-conjugated immune-stimulatory oligonucleotide \[Amph...

Active, not recruiting
Colorectal Cancer
KRAS G12V
Drug: ELI-002 7P

Phase 1, Phase 2

Elicio Therapeutics
Elicio Therapeutics

Philadelphia, Pennsylvania, United States and 27 other locations

This study will evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with adva...

Active, not recruiting
Metastatic Cancer
Advanced Cancer
Drug: Cetuximab
Drug: Afatinib

Phase 1, Phase 2

Mirati Therapeutics
Mirati Therapeutics

Media, Pennsylvania, United States and 231 other locations

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