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Find clinical trials for Colon Cancer in Philadelphia, PA

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Related conditions:

Colorectal Cancer
Colonic Cancer
Cancer
Adenocarcinoma
Lung Cancer
Neoplasm Metastasis
Non-Small-Cell Lung Carcinoma

Colon Cancer trials near Philadelphia, PA, USA:

The Phoenix Trial: Phase II Trial of Cemiplimab for the Non-operative Management of Localized dMMR Colon Cancer

To learn if cemiplimab can help to control dMMR colon cancer....

Enrolling
Colon Cancer
Drug: Cemiplimab

Phase 2

M.D. Anderson Cancer Center
M.D. Anderson Cancer Center

Camden, New Jersey, United States and 4 other locations

doses of selected chemotherapies will be safe and tolerable for cancer patients with advanced solid tumors. The highest tolerated d...

Active, not recruiting
Breast Cancer
Colon Neoplasms
Drug: Erlotinib
Drug: Temsirolimus

Phase 1

AstraZeneca
AstraZeneca

Philadelphia, Pennsylvania, United States and 3 other locations

aggressive and challenging to treat. The study will test whether GSK4418959 alone or in combination with a PD-1 inhibitor agent can decrease tumor...

Enrolling
Endometrial Cancer
Solid Tumor
Drug: GSK4418959
Biological: PD-1 inhibitor

Phase 1, Phase 2

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Philadelphia, Pennsylvania, United States and 12 other locations

This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor ...

Active, not recruiting
Any Solid Tumor
Colon Cancer
Drug: LOXO-292

Phase 1, Phase 2

Lilly
Lilly

Philadelphia, Pennsylvania, United States and 84 other locations

oral LOXO-292 in pediatric participants with an activating rearranged during transfection (RET) alteration and an advanced solid or primary CNS tumor...

Active, not recruiting
Papillary Thyroid Cancer
Medullary Thyroid Cancer
Drug: LOXO-292

Phase 1, Phase 2

Lilly
Lilly

Philadelphia, Pennsylvania, United States and 25 other locations

This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor...

Enrolling
Stage III Colon Cancer
Drug: mFOLFOX6 3-6 month
Device: Signatera test

Phase 2, Phase 3

NRG Oncology
NRG Oncology

Philadelphia, Pennsylvania, United States and 987 other locations

This is a first-in-human, open-label, non-randomized, three-part phase 1 trial of INBRX-109, which is a recombinant humanized tetravalent antibody ta...

Enrolling
Colorectal Adenocarcinoma
Ewing Sarcoma
Drug: Pemetrexed
Drug: INBRX-109

Phase 1

Inhibrx Biosciences, Inc

Philadelphia, Pennsylvania, United States and 33 other locations

of SNS-101, a novel anti VISTA IgG1 monoclonal antibody as monotherapy or in combination with cemiplimab in patients with advanced solid tumors...

Active, not recruiting
Breast Cancer
Uterine Cancer
Drug: Cemiplimab
Drug: SNS-101 (anti-VISTA)

Phase 1, Phase 2

Sensei Biotherapeutics

Philadelphia, Pennsylvania, United States and 9 other locations

This open-label study will evaluate the safety, tolerability, pharmacokinetics and effect on tumor growth following a single intralesional i...

Active, not recruiting
Metastatic Colorectal Cancer
Metastatic Pancreatic Cancer
Drug: PV-10 (10% rose bengal disodium)

Phase 1

Provectus Biopharmaceuticals

Bethlehem, Pennsylvania, United States and 4 other locations

\[Amph-Peptides 7P\]) as adjuvant treatment in subjects with solid tumors with mutated KRAS/NRAS. This study builds on the experience obtain...

Active, not recruiting
Colorectal Cancer
KRAS G12V
Drug: ELI-002 7P

Phase 1, Phase 2

Elicio Therapeutics
Elicio Therapeutics

Philadelphia, Pennsylvania, United States and 27 other locations

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