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Find clinical trials for Colon Cancer in Philadelphia, PA

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Related conditions:

Colorectal Cancer
Colonic Cancer
Cancer
Neoplasm Metastasis
Non-Small-Cell Lung Carcinoma
Adenocarcinoma
Carcinoma

Colon Cancer trials near Philadelphia, PA, USA:

The Phoenix Trial: Phase II Trial of Cemiplimab for the Non-operative Management of Localized DMMR Colon Cancer

To learn if cemiplimab can help to control dMMR colon cancer....

Enrolling
Colon Cancer
Drug: Cemiplimab

Phase 2

M.D. Anderson Cancer Center
M.D. Anderson Cancer Center

Camden, New Jersey, United States and 3 other locations

(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...

Enrolling
Colonic Neoplasms
Neoplasms, Colon
Drug: CAPEOX
Biological: Dostarlimab

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Wynnewood, Pennsylvania, United States and 250 other locations

doses of selected chemotherapies will be safe and tolerable for cancer patients with advanced solid tumors. The highest tolerated d...

Active, not recruiting
Breast Cancer
Colon Neoplasms
Drug: Erlotinib
Drug: Temsirolimus

Phase 1

AstraZeneca
AstraZeneca

Philadelphia, Pennsylvania, United States and 3 other locations

This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor ...

Active, not recruiting
Any Solid Tumor
Colon Cancer
Drug: LOXO-292

Phase 1, Phase 2

Lilly
Lilly

Philadelphia, Pennsylvania, United States and 84 other locations

RSC-101 is a Phase 1a/1b clinical trial of RSC-1255 in adult study participants with advanced solid tumor malignancies who are intolerant of...

Enrolling
Colon Cancer
Lung Cancer
Drug: RSC-1255 Dose Expansion
Drug: RSC-1255 Dose Escalation

Phase 1

Rascal Therapeutics

Philadelphia, Pennsylvania, United States and 4 other locations

oral LOXO-292 in pediatric participants with an activating rearranged during transfection (RET) alteration and an advanced solid or primary CNS tumor...

Active, not recruiting
Papillary Thyroid Cancer
Medullary Thyroid Cancer
Drug: LOXO-292

Phase 1, Phase 2

Lilly
Lilly

Philadelphia, Pennsylvania, United States and 25 other locations

This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor...

Enrolling
Stage III Colon Cancer
Drug: mFOLFOX6 3-6 month
Device: Signatera test

Phase 2, Phase 3

NRG Oncology
NRG Oncology

Philadelphia, Pennsylvania, United States and 927 other locations

This is a first-in-human, open-label, non-randomized, three-part phase 1 trial of INBRX-109, which is a recombinant humanized tetravalent antibody ta...

Enrolling
Colorectal Adenocarcinoma
Ewing Sarcoma
Drug: Pemetrexed
Drug: INBRX-109

Phase 1

Inhibrx Biosciences, Inc

Philadelphia, Pennsylvania, United States and 33 other locations

of SNS-101, a novel anti VISTA IgG1 monoclonal antibody as monotherapy or in combination with cemiplimab in patients with advanced solid tumors...

Enrolling
Breast Cancer
Uterine Cancer
Drug: Cemiplimab
Drug: SNS-101 (anti-VISTA)

Phase 1, Phase 2

Sensei Biotherapeutics

Philadelphia, Pennsylvania, United States and 10 other locations

This open-label study will evaluate the safety, tolerability, pharmacokinetics and effect on tumor growth following a single intralesional i...

Active, not recruiting
Metastatic Colorectal Cancer
Metastatic Pancreatic Cancer
Drug: PV-10 (10% rose bengal disodium)

Phase 1

Provectus Biopharmaceuticals

Bethlehem, Pennsylvania, United States and 4 other locations

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